Lower Serologic Response to COVID-19 mRNA Vaccine in Patients With Inflammatory Bowel Diseases Treated With Anti-TNFα항-TNFα 치료를 받은 염증성 장 질환 환자의 코로나19 mRNA 백신에 대한 혈청학적 반응 감소Observational Study Published on 2022-02-012022-09-11 Journal: Gastroenterology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] administration adverse event adverse events AEs all subject all subjects Anti-spike anti-spike antibody anti-TNF antibody BNT162b2 booster dose comparable coronavirus disease COVID-19 dose doses drug level drug levels enrolled function functional groups HCs healthy control healthy controls high risk IBD infection rate infections Inflammatory bowel disease inflammatory bowel diseases inhibitory Lower magnitude Messenger RNA mounted mRNA mRNA-BNT162b2. multicenter Necrosis not affect Patient patients treated Pfizer Pfizer/BioNTech Prospective Prospective Study remained response Safe safety profile second dose serologic Serologic response serologic responses seronegative seropositive significantly lower stratified therapy TNFα treated treated patients Treatment Vaccine vaccine dose vaccine response vaccine responses [DOI] 10.1053/j.gastro.2021.10.029 PMC 바로가기 [Article Type] Observational Study
Impact of the lockdown period due to the COVID-19 pandemic in patients with inflammatory bowel diseaseObservational Study Published on 2022-02-012022-10-05 Journal: Gastroenterología y hepatología [Category] 임상, [키워드] adherence Adherencia terapéutica analogue analyzed bowel carried coronavirus disease COVID-19 COVID-19 pandemic Descriptive analysis disorders emotional Enfermedad inflamatoria intestinal English Estrés percibido Factor high risk IBD Impact increase in Inflammatory bowel disease intestinal lockdown Logistic regression media median multivariate analyses Pandemia pandemic Patient Perceived Perceived stress Perceived Stress Scale-10 prospectivo PSS-10 PSS-10 score PSS-10 scores Psychological distress quarantine questionnaire reported SARS-CoV-2 scale Spain Spaniard Spanish Stress Symptoms therapeutic therapeutic adherence Treatment Visual women [DOI] 10.1016/j.gastrohep.2021.03.012 PMC 바로가기 [Article Type] Observational Study
Interim analysis of a multicenter registry study of COVID-19 patients with inflammatory bowel disease in Japan (J-COSMOS)Observational Study Published on 2022-01-282022-10-04 Journal: Journal of Gastroenterology [Category] MERS, SARS, 임상, [키워드] age Analysis analyzed Anti-TNF-α antibodies antibodies BMI body mass index Clinical course Cohort conditions coronavirus disease COVID-19 COVID-19 patient COVID-19 severity COVID-19 symptom COVID19 diagnosed with COVID-19 Disease activity had no Health IBD incidence independent risk factor Inflammatory bowel disease Interim Japan Japanese Logistic regression analysis majority multicenter Necrosis nine Older age Patient patients patients with COVID-19 receiving Registered Result SARS-CoV-2 Severe case severity Sex Spread steroid supplementary material the WHO Treatment vaccination with COVID-19 [DOI] 10.1007/s00535-022-01851-1 PMC 바로가기 [Article Type] Observational Study
Risk of infections with ustekinumab and tofacitinib compared to tumor necrosis factor α antagonists in inflammatory bowel diseasesArticle Published on 2022-01-272024-09-04 Journal: Clinical gastroenterology and hepatology : the off [Category] 대상포진, [키워드] biologics IBD infections Pneumonia Safety [DOI] 10.1016/j.cgh.2022.01.013 PMC 바로가기 [Article Type] Article
Real-World Use and Adverse Events of SARS-CoV-2 Vaccination in Greek Patients with Inflammatory Bowel DiseaseArticle Published on 2022-01-272022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] abdominal pain Adverse adverse event AEs age Analysis Clinical characteristics concerning COVID-19 COVID-19 vaccination COVID-19 vaccine Crohn’s disease demographics demonstrated diarrhea disease dose doses Effect female gender Hospitalization IBD inactive Inflammatory bowel disease information injection knowledge Occurrence Patient patients reaction reported safety profile SARS-CoV-2 SARS-CoV-2 vaccination serious AE Symptom systemic Total Treatment ulcerative colitis vaccination Vaccine were excluded [DOI] 10.3390/jcm11030641 PMC 바로가기 [Article Type] Article
Induction of remission with tacrolimus in a patient with severe acute, cortisone refractory ulcerative colitis and severe Covid-19 pneumonia: a case reportCase Report Published on 2022-01-152022-10-27 Journal: BMC Gastroenterology [Category] COVID-19, [키워드] acute respiratory syndrome adjusted Admission Case report clinical response Clinical symptoms clinician coronavirus cortisone cortisone therapy Course COVID-19 COVID-19 pneumonia defined discharged dose High-dose hospital IBD Immunosuppression IMPROVE increased risk induction infected patient Infection Inflammatory Inflammatory bowel disease inhibitor initiated intravenous managing medication outbreak pandemic Patient patients positive Prednisolone presenting regimen risk SARS-CoV-2 severe coronavirus disease Symptoms the patient therapeutic option therapy treat Treatment ulcerative colitis viral infection viral reactivation was tested [DOI] 10.1186/s12876-022-02094-3 PMC 바로가기 [Article Type] Case Report
Induction of remission with tacrolimus in a patient with severe acute, cortisone refractory ulcerative colitis and severe Covid-19 pneumonia: a case reportCase Report Published on 2022-01-152022-10-27 Journal: BMC Gastroenterology [Category] Coronavirus, COVID-19, Fulltext, SARS, [키워드] acute respiratory syndrome adjusted Admission Case report clinical response Clinical symptoms clinician coronavirus cortisone cortisone therapy Course COVID-19 COVID-19 pneumonia defined discharged dose High-dose hospital IBD Immunosuppression IMPROVE increased risk induction infected patient Infection Inflammatory Inflammatory bowel disease inhibitor initiated intravenous managing medication outbreak pandemic Patient patients positive Prednisolone presenting regimen risk SARS-CoV-2 severe coronavirus disease Symptoms the patient therapeutic option therapy treat Treatment ulcerative colitis viral infection viral reactivation was tested [DOI] 10.1186/s12876-022-02094-3 PMC 바로가기 [Article Type] Case Report
Nationwide COVID-19-EII Study: Incidence, Environmental Risk Factors and Long-Term Follow-Up of Patients with Inflammatory Bowel Disease and COVID-19 of the ENEIDA RegistryArticle Published on 2022-01-142022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Comorbidity Contagion Course COVID-19 COVID-19 in patient death died drug Factor General population hospitalisation Hospitalization IBD ICU immunosuppressed patients incidence increased mortality Inflammatory bowel disease lockdown measure Mortality Patient patients with COVID-19 Prognosis prospective observational study registry reported required Result risk factor SARS-CoV-2 severe COVID-19 Transmission were infected [DOI] 10.3390/jcm11020421 PMC 바로가기 [Article Type] Article
Humoral Immune Response in IBD Patients Three and Six Months after Vaccination with the SARS-CoV-2 mRNA Vaccines mRNA-1273 and BNT162b2Article Published on 2022-01-132022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] acute respiratory syndrome anti-TNF approach BNT162b2 booster coronavirus disease COVID-19 COVID-19 mRNA Vaccination domain Efficacy Evidence examined healthy control healthy subjects humoral IBD IBD patients IgG antibody Immunosuppressed Inflammatory bowel disease Month mRNA mRNA-1273 Necrosis neutralization neutralizing capacity not differ pandemic Patient patients patients treated Prospective Study response SARS-CoV-2 second vaccination Seroconversion seroconversion rate significant difference significantly lower spike-protein sVNT the SARS-CoV-2 therapy TNF two group vaccination Vaccine [DOI] 10.3390/biomedicines10010171 PMC 바로가기 [Article Type] Article
Ambulatory care management of 69 patients with acute severe ulcerative colitis in comparison to 695 inpatients: insights from a multicentre UK cohort study695명의 입원 환자와 비교하여 급성 중증 궤양성 대장염 환자 69명의 외래 치료 관리: 영국 다기관 코호트 연구의 통찰력Multicenter Study Published on 2022-01-012022-09-11 Journal: BMJ open gastroenterology [Category] SARS, 치료기술, [키워드] acceptability age ambulatory Ambulatory care ambulatory patient ambulatory patients Analysis Aside bowel Care Cohort cohort study cohorts colectomy collected Corticosteroid COVID-19 criteria detect Diagnosis discharged disease disease phenotype Effectiveness Eligible patients evaluated flexible flexible sigmoidoscopy Follow-up Health Service health service research hospital Hospital admission hospital management hospitalised IBD IBD clinical index Inflammatory Inflammatory bowel disease intravenous less management Mortality multicentre no significant difference no significant differences outcome outcome measure Pathways Patient patients treated performed phenotype physician post-hoc analysis Primary outcome PROTECT readmission recruited registration number required rescue secondary secondary outcome Secondary outcomes Steroids Stool culture subsequent surgery surgery for IBD therapy Treatment Treatment outcome ulcerative colitis used data [DOI] 10.1136/bmjgast-2021-000763 PMC 바로가기 [Article Type] Multicenter Study