immunomodulatory effect – Page 6 – Communicable Diseases Research

At the Crossroads: COVID-19 and Immune-Checkpoint Blockade for Cancer

갈림길에서: COVID-19와 암에 대한 면역 관문 차단

Article

Published on 2021-03-012022-09-11
Journal: Cancer immunology research [Category] 바이오마커,

Immunomodulatory Effects of Azithromycin Revisited: Potential Applications to COVID-19

Immunology

Published on 2021-02-122022-11-01
Journal: Frontiers in Immunology [Category] COVID-19,

[키워드] accelerated alteration Antiviral effect application autophagy Azithromycin benefit clearance Clinical use contribute Course COVID-19 COVID-19 immune response COVID-19 pandemic Cytokine storm death defined early stage Effect effective Efficacy Evidence Factor function identify immune mechanism immune response immunomodulation immunomodulatory immunomodulatory effect immunomodulatory therapy immunosuppressive Infection Inflammation inflammatory cell infiltration investigated late stage Lung pathology macrophages mechanism Multiple neutrophil patients patients with COVID-19 Potential pro-inflammatory cytokine progression pursuit Regulatory severe disease shown Stage Support the disease therapeutic therapy viral burden virus while
[DOI] 10.3389/fimmu.2021.574425 PMC 바로가기 [Article Type] Immunology

Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways

여러 바이러스 관련 경로에 의한 항-COVID-19 TCM 공식의 면역 조절 효과 평가

Comment

Published on 2021-02-042022-08-31
Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 신약개발, 치료제,

[키워드] Computational biology and bioinformatics immunomodulatory effect Infectious diseases pathway Systems biology TCM
[DOI] 10.1038/s41392-021-00475-w PMC 바로가기 [Article Type] Comment

Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19

COVID-19 환자의 복합 요법에서 조혈모세포 분화 활성화제를 사용한 결과 및 전망

Article

Published on 2021-02-012022-09-11
Journal: Stem cell reviews and reports [Category] 유전자 메커니즘,

[키워드] accelerated activator addition biological activity blood clot Blood clots C-reactive protein carbon complex Concentration control group Coronavirus infection COVID-19 COVID-19 patients cytokine D-dimer decrease differentiation hematopoietic Hematopoietic stem cell hematopoietic stem cells Hemostasis hydrogen hydrogen atom hydrogen atoms IL-6 Immunity immunomodulatory effect Inclusion mechanism nitrogen oxygen paper Patient patients with COVID-19 peptide peptides phosphorus pro-inflammatory cytokine pro-inflammatory cytokine IL-6 rationale reduce Result risk SARS-CoV-2 virus shown Standard Standard therapy standard treatment STEM T cell Thymalin. Treatment treatment method with COVID-19
[DOI] 10.1007/s12015-020-10087-6 PMC 바로가기 [Article Type] Article

Umbilical cord: an allogenic tissue for potential treatment of COVID-19

탯줄: COVID-19의 잠재적인 치료를 위한 동종 조직

Review

Published on 2021-01-012022-09-11
Journal: Human Cell [Category] 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome alveolar alveolar damage ARDS associated symptoms autologous best chemokine chemokines clinical Clinical studies clinical study compassionate use complications controlled trials coronavirus COVID-19 COVID-19 pandemic Cytokines demonstrated detrimental effective Efficacy Evidence Factors globe Health care Health care system health care systems Hope immunomodulatory immunomodulatory effect lead limitations manuscript mesenchymal stem cell Mesenchymal stem cells MSC MSCs organ damage positioned Potential treatment pro-inflammatory cytokine pro-inflammatory cytokines randomized, controlled trial reduce regenerative respiratory distress Respiratory distress syndrome Safe SARS-COV-2 infection Symptom Symptoms syndrome therapeutic use therapy for COVID-19 tissue tissue repair treat Treatment treatment of COVID-19 umbilical Umbilical cord Vaccine Wharton's Jelly Wharton’s jelly Wharton’s jelly.
[DOI] 10.1007/s13577-020-00444-5 PMC 바로가기 [Article Type] Review

The Systematic Effect of Mesenchymal Stem Cell Therapy in Critical COVID-19 Patients: A Prospective Double Controlled Trial

중증 코로나19 환자에서 중간엽 줄기세포 치료의 체계적인 효과: 전향적 이중 대조 시험

Controlled Clinical Trial

Published on 2021-01-012022-09-11
Journal: Cell transplantation [Category] 유전자 메커니즘, 임상,

[키워드] Analysis anti-inflammatory cytokine anti-inflammatory cytokines Apoptosis Biochemical parameters CD16 CD19 CD3 CD4 CD45 CD56 CD8 Cell cellular chemokines clinical manifestation clinical manifestations clinical trial Controlled COVID-19 COVID-19 patient COVID-19 patients Critical critical cases Critically ill critically ill COVID-19 patients critically ill patients CRP level CRP levels cytokine Cytokine storm Cytokines demonstrated died dose Effect evaluate evaluated fibrinogen group groups growth growth factor Growth factors HLA-DR IFNγ IL-10 IL-12 IL-13 IL-17A IL-1ra IL-2 IL-6 immunomodulatory effect immunomodulatory effects intravenously investigated KGF lymphocyte Lymphocyte subsets marker matrix metalloproteinases mechanism of action mesenchymal stem cell Mesenchymal stem cells moderate MSC MSCs Neutrophils NGF overall mortality Patient positive proinflammatory proinflammatory cytokines Prospective reducing mortality separated Serum ferritin significantly statistical STEM stem cell TGF-β the cytokine storm therapy tissue regeneration treated Treatment VEGF
[DOI] 10.1177/09636897211024942 PMC 바로가기 [Article Type] Controlled Clinical Trial

Lactobacillus casei CRL431 modulates hemostatic activation induced by protein malnourishment and pneumococcal respiratory infection

article

Published on 2020-12-312024-09-01
Journal: Applied Microbiology and Biotechnology [Category] 폐렴구균 감염증,

[키워드] Hemostatic activation immunomodulatory effect L. casei CRL431 Malnourished mice
[Article Type] article

Cellular and Molecular Immunology Approaches for the Development of Immunotherapies against the New Coronavirus (SARS-CoV-2): Challenges to Near-Future Breakthroughs

새로운 코로나바이러스(SARS-CoV-2)에 대한 면역요법 개발을 위한 세포 및 분자 면역학 접근법: 가까운 미래의 돌파구에 대한 도전

Review

Published on 2020-12-192022-09-10
Journal: Journal of Immunology Research [Category] MERS, SARS, 진단, 치료제,

[키워드] acute respiratory syndrome addressed approach caused cellular and molecular challenge clinical outcomes coronavirus Course COVID-19 development dysfunction Effect Factor health system health systems hemostatic disorder hemostatic disorders high mortality rate Host immunology immunomodulatory effect immunopathology immunotherapies Immunotherapy improve clinical outcomes Infectious disease information innate immune response Interaction knowledge mechanism New New coronavirus pulmonary tract respiratory respiratory viral disease SARS-CoV-2 Scientific community Severe acute respiratory syndrome therapy Treatment treatment of COVID-19 Trigger Vaccine Vaccines Viral viral disease
[DOI] 10.1155/2020/8827670 PMC 바로가기 [Article Type] Review

Clinical stage molecule PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2

임상 단계 분자 PT150은 SARS-CoV-2에 대한 항바이러스 활성이 있는 글루코코르티코이드 및 안드로겐 수용체의 조절제입니다.

Article

Published on 2020-12-012022-09-11
Journal: Cell cycle (Georgetown, Tex.) [Category] SARS, 치료제,

[키워드] ACE2 activity androgen Androgen receptor Anti-SARS-CoV-2 Activity antidepressant Antiviral antiviral activities antiviral activity Cell cellular clinical clinical trial Concentration cortisol COVID-19 COVID-19 progression downregulation effective epithelial lining glucocorticoid Glucocorticoid antagonist Glucocorticoid receptor glucocorticoid receptor (GR immunomodulatory effect IND inhibitory member modulating modulation molecules Phase 1 Phase 2 phase 2 clinical trials platform predominant PT150 receptor safety profile SARS-CoV-2 suggested tested therapeutic TMPRSS2 TMPRSS2 expression variety virus
[DOI] 10.1080/15384101.2020.1859752 PMC 바로가기 [Article Type] Article

Garlic ( Allium sativum L.): a potential unique therapeutic food rich in organosulfur and flavonoid compounds to fight with COVID-19

마늘( Allium sativum L.): COVID-19와 싸울 수 있는 유기황 및 플라보노이드 화합물이 풍부한 잠재적인 독특한 치료 식품

Letter to the Editor

Published on 2020-11-182022-08-31
Journal: Nutrition Journal [Category] 치료제,