Factors that predict severity of infection and seroconversion in immunocompromised children and adolescents with COVID-19 infectionCOVID-19 감염으로 면역저하된 소아 및 청소년에서 감염 및 혈청전환의 중증도를 예측하는 요인Observational Study Published on 2022-08-032022-09-12 Journal: Frontiers in Immunology [Category] SARS, 임상, 진단, [키워드] Absolute lymphocyte count absolute neutrophil count Analysis ANC anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Antibody Response blood sample body mass index Cancer Cell Chemotherapy children Clinical severity comorbid condition COVID COVID 19 COVID-19 infection Critical Cutoff defined determine died Factor FIVE Hematologic malignancy Hematological malignancy high-risk population Hospitalized ICU Immunocompromised Immunocompromised patient immunosuppressive Infection Laboratory less Level lowest median moderate multivariable model observation outcome outcomes Patient patients PCR Pediatric patient predict Predictive receiving required Respiratory Support SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection Seroconversion seroconversion rate severity Severity of infection stem cell transplant steroid the patient therapy treated univariable vaccination variable was used with COVID-19 [DOI] 10.3389/fimmu.2022.919762 PMC 바로가기 [Article Type] Observational Study
Annual risk of falls resulting in emergency department and hospital attendances for older people: an observational study of 781,081 individuals living in Wales (United Kingdom) including deprivation, frailty and dementia diagnoses between 2010 and 2020Observational Study Published on 2022-08-022022-10-05 Journal: Age and Ageing [Category] 임상, [키워드] Admission age analysed Annual association COVID-19 COVID-19 pandemic cross-sectional Dementia Deprivation diagnose Falls frailty highest hospital Hospital admission individual individuals less Logistic lowest male Mild moderate Odds ratio Older older people outcome person year reduction in resulting risk United Kingdom [DOI] 10.1093/ageing/afac176 PMC 바로가기 [Article Type] Observational Study
The Clinical Efficacy and Safety of Anti-Viral Agents for Non-Hospitalized Patients with COVID-19: A Systematic Review and Network Meta-Analysis of Randomized Controlled TrialsCOVID-19를 가진 비 병원 환자에 대한 항 바이러스 제제의 임상 효능 및 안전성 : 무작위 대조 시험의 체계적인 검토 및 네트워크 메타 분석Review Published on 2022-08-022022-08-31 Journal: Viruses [Category] meta-analysis, 임상, 치료제, [키워드] adverse event adverse events agent anti-viral agent anti-viral agents Anti-viral treatment best calculated clinical Clinical efficacy clinical setting Cochrane Library Controlled controlled trials COVID-19 death determined by Disease progression followed by Hospitalization increased risk Intravenous remdesivir investigated lowest molnupiravir network Network meta-analysis Nirmatrelvir nirmatrelvir plus ritonavir Patient patients with COVID-19 Placebo Probability Randomized controlled trial RCT RCTs receiving registry Remdesivir review risk risk of COVID-19 Ritonavir Safety searched shown significantly lower the WHO tolerable Treatment Web of Science WHO International Clinical Trials Registry Platform [DOI] 10.3390/v14081706 PMC 바로가기 [Article Type] Review
Deep transfer learning for the recognition of types of face masks as a core measure to prevent the transmission of COVID-19Research article Published on 2022-08-012022-10-05 Journal: Applied Soft Computing [Category] 치료기술, [키워드] Accuracy appear caused COVID-19 deep deep learning detection system effective Experimental result Face mask Face masks highest Infection lowest measure Prevent Recognition spread of COVID-19 surgical transfer transfer learning Transmission virus virus transmission [DOI] 10.1016/j.asoc.2022.109207 [Article Type] Research article
Risks of catching COVID-19 according to vaccination status of healthcare workers during the SARS-CoV-2 Delta variant dominant period and their clinical characteristicsSARS-CoV-2 Delta 변종 우세 기간 동안 의료 종사자의 예방 접종 상태 및 임상 특성에 따른 COVID-19 감염 위험Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 BioNTech C-reactive protein Clinical characteristics Clinical course CoronaVac coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 transmission CRP D-dimer delta variant dimer dominant dose ferritin HCW HCWs healthcare healthcare worker Healthcare workers Hospitalization investigated lowest lymphocyte Lymphocyte count Not needed pandemic Patient patients patients with COVID-19 required SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significantly higher statistically significant status the disease the SARS-CoV-2 training transmission rate Turkey vaccination Vaccination Status Vaccine [DOI] 10.1002/jmv.27778 PMC 바로가기 [Article Type] Article
Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy면역억제 요법을 받는 환자에서 표준 및 3차 접종 SARS-CoV-2 백신 접종의 면역원성과 안전성Observational Study Published on 2022-08-012022-09-12 Journal: Arthritis & rheumatology (Hoboken, N.J.) [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Adult patient adverse event age antibody arbitrary unit characterized combination therapy comparable Control controls defined disease dose evaluate facilitate full-length healthy healthy control healthy controls IgG antibody Immune-mediated inflammatory disease immunogenicity immunosuppressive inhibitor interquartile range jak inhibitors lowest median Necrosis Patient patient group patients performed predictor proportion prospective observational study psoriatic arthritis RBD receiving regimen Responder responders rheumatoid arthritis risk RNA-1273 Safe Safety safety profile SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Serologic response Spike protein spondyloarthritis Standard Support the receptor-binding domain the SARS-CoV-2 therapy ulcerative colitis vaccination Vaccine vaccine dose vaccine response [DOI] 10.1002/art.42153 PMC 바로가기 [Article Type] Observational Study
Rapid evaluation of COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 variants by analysis of genetic distance유전적 거리 분석을 통한 SARS-CoV-2 변이체의 증상 감염에 대한 COVID-19 백신 효과의 신속한 평가Article Published on 2022-08-012022-09-11 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 임상, [키워드] 95% prediction interval accounted acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed applied circulating clinical trial collected Concordance coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine delta variant Effectiveness Efficacy Genetic Genetic variant highest lowest mixed-effects model mRNA vaccine observational study offer omicron pandemic platform predict predicted Predictive protective effect Protective effects Public health responses Rapid real time Receptor-binding domain regions reported SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 spike protein SARS-CoV-2 variant severe acute respiratory syndrome Coronavirus Spike protein symptomatic infection the receptor-binding domain the SARS-CoV-2 the vaccine Vaccine vaccine platform vaccine strain variant variants of concern virus [DOI] 10.1038/s41591-022-01877-1 PMC 바로가기 [Article Type] Article
Levels of SARS-CoV-2 antibodies among fully vaccinated individuals with Delta or Omicron variant breakthrough infectionsDelta 또는 Omicron 변이형 돌발성 감염이 있는 완전 예방접종을 받은 개인의 SARS-CoV-2 항체 수준Observational Study Published on 2022-08-012022-09-11 Journal: Nature Communications [Category] SARS, 변종, 임상, 진단, 치료법, [키워드] 95% CI anti-Spike IgG anti-spike IgG level anti-spike IgG levels booster vaccination Breakthrough infection breakthrough infections Cohort database Delta delta variant determine highest IgG levels Immunity incidence rate Infection Level lowest Microbiology no significant difference no significant differences Observational cohort study omicron Omicron variants Participants Poisson regression Quantitative rate ratio risk SARS-CoV-2 SARS-CoV-2 anti-spike IgG SARS-CoV-2 antibody SARS-CoV-2 vaccination SARS-CoV-2 variants vaccinated individual Vaccine variant variants of concern was determined were measured [DOI] 10.1038/s41467-022-32254-8 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 infection in cancer patients on active therapy after the booster dose of mRNA vaccinesmRNA 백신 추가 접종 후 활성 요법을 받는 암 환자의 SARS-CoV-2 감염Article Published on 2022-08-012022-09-11 Journal: European journal of cancer (Oxford, England : 1990 [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] active treatment anti-Spike IgG booster booster dose Booster vaccine cancer patient Cancer patients center Cohort COVID-19 Delta dose Follow-up geometric mean geometric mean titer geometric mean titers Health care Health care worker healthy subject healthy subjects indicate investigated Italy lowest malignancies median value microneutralization Microneutralization assay mRNA vaccine mRNA vaccines Nasopharyngeal swab Neutralizing antibodies neutralizing antibody Occurrence occurrence of COVID-19 omicron Omicron variants outbreak Patient positive potential risk proportion protective role required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants serological Siena solid malignancies solid malignancy solid tumor solid tumors tested the median the SARS-CoV-2 therapy Treatment tumors Type university Vaccine variants [DOI] 10.1016/j.ejca.2022.05.018 PMC 바로가기 [Article Type] Article
Human adenovirus (HAdV) infection in children with acute respiratory tract infections in Guangzhou, China, 2010-2021: a molecular epidemiology study2010-2021년 중국 광저우에서 급성 호흡기 감염이 있는 어린이의 인간 아데노바이러스(HAdV) 감염: 분자 역학 연구Article Published on 2022-08-012022-09-11 Journal: World Journal of Pediatrics [Category] 유전자 메커니즘, 치료기술, [키워드] acute hepatitis acute respiratory illness acute respiratory tract infection Adenovirus adenovirus infection ARI average mortality center children China Community conducted COVID-19 COVID-19 outbreak demonstrated described diagnosed Diseases distribution dominant dropped epidemic peak Epidemiology FIVE foundation Frequency Guangzhou Guangzhou, China Hepatitis Human Human adenovirus Infection Intervention life-threatening lowest Molecular epidemiology pathogen peaking pediatric Phylogenetic analysis proportion provide ranged Real-time PCR reduced respiratory tract respiratory tract infection Retrospective study risk Severe acute hepatitis severe cases severe disease shift shifting significant increase southern China specimen subtype Subtypes summer Transmission variety was recorded was used [DOI] 10.1007/s12519-022-00590-w PMC 바로가기 [Article Type] Article