Medical conditions – Page 6 – Communicable Diseases Research

Adapting the Surveillance Platform for Enteric and Respiratory Infectious Organisms at United States Veterans Affairs Medical Centers (SUPERNOVA) for COVID-19 Among Hospitalized Adults: Surveillance Protocol

입원한 성인 중 COVID-19에 대한 미국 재향 군인 의료 센터(SUPERNOVA)의 장 및 호흡기 감염성 유기체에 대한 감시 플랫폼 조정: 감시 프로토콜

Public Health

Published on 2021-10-292022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, 치료기술,

COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes

Article

Published on 2021-10-222022-10-31
Journal: Children [Category] COVID-19,

A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®

면역 저하 환자에서 승인된 SARS-CoV-2 백신을 평가하기 위한 시험 플랫폼: mRNA 백신 Comirnaty®와 COVID-19 mRNA를 비교하는 파일럿 시험을 위한 첫 번째 하위 프로토콜 Vaccine Moderna®

Study Protocol

Published on 2021-10-212022-09-10
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] Antibody Response approaches approved baseline clinical trial Cohort cohorts collected data confidence interval contagious Controlled trial coronavirus coronavirus SARS-CoV-2 COVID-19 disease Efficacy Efficacy and safety eligible Endpoint endpoints favor feasibility first vaccination flexible foundation Frame groups highest HIV HIV patient HIV patients Immunocompromised Immunocompromised patient Immunocompromised patients information Intervention Medical conditions Missing data mRNA mRNA vaccine multicenter non-inferiority margin Open-label Organ transplant outcome pandemic Patient patient recruitment Pfizer/BioNTech pilot study Platform trial positive antibody response primary clinical outcome Program proportion protocol randomization Randomized Randomized controlled trial Randomized controlled trial, HIV RCT reached reactivity receiving recipients required Sample size SARS-CoV-2 SARS-CoV-2 vaccine Science Statistical power STCS Switzerland Transplant treatment arm Trial trial platform Trial registration two-sided type I type I error Vaccine Wuhan Wuhan, China
[DOI] 10.1186/s13063-021-05664-0 PMC 바로가기 [Article Type] Study Protocol

Nasal delivery of single-domain antibody improves symptoms of SARS-CoV-2 infection in an animal model

단일 도메인 항체의 비강 전달은 동물 모델에서 SARS-CoV-2 감염의 증상을 개선합니다

Research Article

Published on 2021-10-142022-09-10
Journal: PLoS Pathogens [Category] MERS, SARS, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration alveolar amplified animal model antibody Behavior block blood stream can not cause caused Cell cells conditions coronavirus COVID-19 COVID-19 patients cryo Cryo-electron microscopy cytokine demonstrated drug drug candidates electron microscopy fusing hamster hamsters host cell host cell membrane human lung organoids immune reaction IMPROVE in vitro infected cell infected cells infective inhibited lead less life-threatening lung Medical conditions membrane Microscopy N-terminal domain nasal nebulizer neutralize neutralized nose occur potency Prevent prevented produced progeny receptor Receptor binding domain reducing Reinfection respiratory risk S protein SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe pneumonia Symptom Symptoms the disease therapeutic drug TMPRSS2 treat treated Treatment typical symptom typical symptoms Vaccine Viral viral membrane virus weight loss while
[DOI] 10.1371/journal.ppat.1009542 PMC 바로가기 [Article Type] Research Article

Attitudes About COVID-19 and Health (ATTACH): Online Survey and Mixed Methods Study

Original Paper

Published on 2021-10-072022-10-31
Journal: JMIR Mental Health [Category] COVID-19,

[키워드] 95% CIs Attitude baseline Baseline assessment Care changes Characteristics Cohort collected correlations COVID-19 COVID-19 pandemic cross-sectional analysis Deprivation disorder Factor female First wave Future Generalized linear model Government had more Health Hierarchical Impact Implications indicated International linear regression analyses longitudinal study measure Medical conditions medical illness Mental mental health mental health burden Mental health disorder Mitigation strategies objective outcome outcomes pandemic participant Pearson physical predictor progressed Psychological Quality of life question reduced reported response Result risk social distancing measures social isolation Sociodemographic spread of COVID-19 study participant survey The United States United Kingdom United States white
[DOI] 10.2196/29963 PMC 바로가기 [Article Type] Original Paper

Mucormycosis and COVID-19: An epidemic within a pandemic in India

Mucormycosis와 COVID-19: 인도에서 유행하는 전염병

Observational Study

Published on 2021-10-012022-09-11
Journal: Mycoses [Category] 임상, 치료제,

[키워드] age Anti-viral Antibiotics biochemical cause Characteristics clinical Clinical features Clinical presentations collected consecutive patient coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids Course COVID-19 COVID-19 diagnosis COVID-19 illness COVID-19 infection COVID-19 patient COVID-19 patients demography diabete diabetes Diabetes Mellitus diagnosed Diagnosis died disease elapsed Epidemic evaluated Factors glycaemic control high mortality Immunosuppressed increase India Infection invasive ventilation majority mechanical ventilation Medical conditions medication MOST Mucormycosis occur outcome oxygen oxygen supplementation pandemic Patient patients with COVID-19 Pneumonia populations required risk Secondary infection secondary infections subject suffered suspicion systemic corticosteroids the patient Treatment use of corticosteroid vaccine dose were recorded widespread
[DOI] 10.1111/myc.13353 PMC 바로가기 [Article Type] Observational Study

Tracking Self-reported Symptoms and Medical Conditions on Social Media During the COVID-19 Pandemic: Infodemiological Study

Original Paper

Published on 2021-09-282022-10-31
Journal: JMIR Public Health and Surveillance [Category] COVID-19,

[키워드] Algorithm Anxiety average calculated Central nervous system change changed changes in condition correlated correlation coughing COVID-19 COVID-19 case COVID-19 pandemic death deaths Depression determine disorder ENhance fatigue fluctuation Frequency health conditions help identify Impact individual Infectious disease Influenza information infoveillance media medical condition Medical conditions mental health natural language processing objective offer Pain pandemic Pearson correlation coefficient Population Positive predictive value public health public health surveillance real time Result sensitivity significantly social media statistically significant study period Surveillance Symptom Symptoms the United State The United States these symptom weight loss
[DOI] 10.2196/29413 PMC 바로가기 [Article Type] Original Paper

Effectiveness of Covid-19 Vaccines in Ambulatory and Inpatient Care Settings

Original Article

Published on 2021-09-082022-11-01
Journal: The New England Journal of Medicine [Category] COVID-19, Fulltext, MERS,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome Ad26.COV2.S vaccine adjusted Admission Adults affected age ambulatory black BNT162b2 Care center circulation clinics conducted Control coronavirus coronavirus disease effective Effectiveness Electronic health record Hispanic hospital Hospitalization ICU ICU admission immunization Infection Inpatient intensive care laboratory-confirmed SARS-CoV-2 infection Local Medical conditions Messenger RNA molecular mRNA mRNA-1273 vaccine Older Patient patients Population Positive test ranged Result SARS-CoV-2 SARS-COV-2 infection second dose setting symptomatic the United State the vaccine vaccination Vaccine virus
[DOI] 10.1056/NEJMoa2110362 PMC 바로가기 [Article Type] Original Article

Risk factors for hospitalization among persons with COVID-19—Colorado

Research Article

Published on 2021-09-022022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] 95% confidence interval adjust adjusted odds ratio age arrhythmia can be used Characteristics Clinical management collected confounding factors coronavirus disease COVID-19 COVID-19 case demographics Electronic health records Evidence facilitate Factor help Hospitalization Hospitalized hypertension hypoxemic identify illness onset IMPROVE laboratory-confirmed Male sex medical condition Medical conditions medication medications MOST multivariable analysis obesity objective Oxygen requirement Patient patient questionnaire populations public health questionnaire Randomly resource Respiratory failure Result risk factor selected significantly social history syndrome
[DOI] 10.1371/journal.pone.0256917 PMC 바로가기 [Article Type] Research Article

An organ systems-based review of outcomes associated with sleep apnea in hospitalized patients

6700

Published on 2021-08-272022-10-30
Journal: Medicine [Category] COVID-19, MERS, SARS,