A Survey Among Italian Physicians During COVID-19 Outbreak. Could Bacillus Calmette–Guérin Vaccine Be Effective Against SARS-CoV2?Pharmacology Published on 2021-05-032022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Against age asymptomatic form Bacille Calmette-Guerin vaccine Bacillus BCG BCG vaccination clinically Cohort Committee Contact COVID-19 COVID-19 infection Data analysis demonstrated distress Epidemiological study Epidemiology evaluate Evidence Infection Innate immunity Italian Natural killer cells no significant difference occurred pauci-symptomatic performed period prevalence physician Pneumonia Prevalence prevalence of COVID-19 professional protective role questionnaire SARS-CoV2 SARS-CoV2 infection subject survey the WHO trained immunity trials vaccination Vaccine was performed was recorded were infected were recorded were used WHO [DOI] 10.3389/fphar.2021.646570 PMC 바로가기 [Article Type] Pharmacology
Natural killer cells play an important role in virus infection control: Antiviral mechanism, subset expansion and clinical applicationReview Article Published on 2021-04-202023-06-03 Journal: Clinical immunology (Orlando, Fla.) [Category] B형 간염, MERS, SARS, [키워드] CMV COVID-19 HBV HIV Natural killer cells [DOI] 10.1016/j.clim.2021.108727 PMC 바로가기 [Article Type] Review Article
Targeting SLC1A5 and SLC3A2/SLC7A5 as a Potential Strategy to Strengthen Anti-Tumor Immunity in the Tumor MicroenvironmentImmunology Published on 2021-04-192022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] accumulating Acidic activate addition Amino acid amino acid transporter anti-tumor immunity c-MYC Cancer caused Cell cell metabolism chimeric antigen receptor demonstrated ENhance Evidence Express expression function functions Glucose Glutamine growth hypoxic Immune cell immune cells immunometabolism Immunotherapy induce infiltration Invasion leucine limitation metabolism metabolites mTORC1 Natural killer cells nutrient transporters overcome plasma membrane Potential proliferation promote regulatory pathway required robust SLC1A5 SLC3A2 SLC7A5 Strategy subcellular subunit T cells targeting therapy transcription factor Tumor tumor microenvironment tumors [DOI] 10.3389/fimmu.2021.624324 PMC 바로가기 [Article Type] Immunology
Do COVID-19 Infections Result in a Different Form of Secondary Hemophagocytic LymphohistiocytosisCOVID-19 감염은 다른 형태의 2차 혈구탐식성 림프조직구증을 초래합니까?Review Published on 2021-03-152022-09-10 Journal: International Journal of Molecular Sciences [Category] 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 benefit biochemical Biomarker caused CD163 coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria cytokine Cytokine storm Diagnosis Diagnostic Criteria effective feature form hemophagocytic lymphohistiocytosis HLH identify Immunosuppression macrophage activation syndrome morbidity and mortality Natural killer cells NK cell pandemic question raising recent respiratory Result SARS-CoV-2 secondary severe acute respiratory syndrome Coronavirus severe COVID-19 severe COVID-19 patients Treatment [DOI] 10.3390/ijms22062967 PMC 바로가기 [Article Type] Review
SARS-CoV-2 infection associated with hepatitis in an infant with X-linked severe combined immunodeficiencyX-연관 중증 복합 면역결핍증이 있는 유아의 간염과 관련된 SARS-CoV-2 감염Case Reports Published on 2021-03-012022-09-11 Journal: Clinical immunology (Orlando, Fla.) [Category] SARS, 치료기술, [키워드] adaptive Adaptive immunity Allogeneic Antigen B cells caused CD34 Cell clinically combined immunodeficiency Conditioning convalescent plasma COVID-19 deficiencies deficiency disorder Donor dysfunction Gene therapy Hepatitis IL-2 receptor Immunity immunodeficiency Inborn error inborn errors of immunity Infant infected with SARS-CoV-2 Mutation Nasopharyngeal swab nasopharyngeal swabs Natural killer cells NK cells opportunistic Infections Patient respiratory respiratory symptom respiratory symptoms resulting RT-PCR SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 specific antibodies SCID selected severe combined immunodeficiency specific antibodies stem cell Transplant transplantation treated X-linked [DOI] 10.1016/j.clim.2020.108662 PMC 바로가기 [Article Type] Case Reports
Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children소아에서 SARS-CoV-2 감염의 급성 및 회복기 동안의 타고난 세포 프로필Article Published on 2021-02-172022-09-10 Journal: Nature Communications [Category] MERS, 유전자 메커니즘, 진단, [키워드] activated neutrophil Activated neutrophils acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 CD63 cell profile children circulating classical clinically convalescent convalescent phase coronavirus Course COVID-19 dendritic cell dendritic cells disease immune responses immunological immunological mechanism Immunopathogenesis infected children Infection Infectious diseases Innate innate immune response innate immune system Innate immunity low-density Mild mild SARS-CoV-2 infection monocyte Monocytes natural killer cell Natural killer cells neutrophil Neutrophils non-classical monocyte Non-classical monocytes observé PCR testing proportion reduced respiratory SARS-CoV-2 SARS-COV-2 infection subset [DOI] 10.1038/s41467-021-21414-x PMC 바로가기 [Article Type] Article
Inosine Pranobex Significantly Decreased the Case-Fatality Rate among PCR Positive Elderly with SARS-CoV-2 at Three Nursing Homes in the Czech RepublicCommunication Published on 2020-12-162022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acute respiratory viral infection affected age all age group Case-fatality rate CFR COVID-19 COVID-19 pandemic COVID-19 patients Czech Republic Decreased demonstrated effective elderly Epidemic home inosine pranobex Ireland Natural killer cells Nursing nursing homes Odds ratio PCR Rate reduced SARS-CoV-2 significant difference significantly statistically significant tested the SARS-CoV-2 virus Treatment Trial viral respiratory infections [DOI] 10.3390/pathogens9121055 PMC 바로가기 [Article Type] Communication
Can Natural Killer Cells Be a Principal Player in Anti-SARS-CoV-2 Immunity?Immunology Published on 2020-12-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Can COVID-19 immunomodulatory Immunotherapy natural Natural killer cells principal SARS-COV-2 infection [DOI] 10.3389/fimmu.2020.586765 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2 Infection and Cardioncology: From Cardiometabolic Risk Factors to Outcomes in Cancer PatientsReview Published on 2020-11-102022-10-31 Journal: Cancers [Category] COVID-19, [키워드] active cancer acute respiratory distress addition angiotensin-converting enzyme 2 Anticancer therapy arrhythmia Cancer cancer patient Cancer patients cardiac event cardiac myocytes cardioncology cardiovascular disease cardiovascular diseases Cardiovascular events caused changed Chemotherapy clinical study Coagulation coagulative Comorbidity complications of COVID-19 Contamination coronavirus COVID-19 Cytokines cytotoxic T lymphocytes death defined diabetes Diseases Effect exacerbated expressed Factor gastro-intestinal tract healthy high risk higher risk highlight Hyperactivation Hyperinflammatory hypertension Inflammation interact Lungs macrophages magnitude management morbidity Mortality Multiorgan multiorgan failure myocardial injury myocarditis Natural killer cells outcome pandemic Patient patients Perspective Prognosis Radiotherapy recommendation reduce retrospective risk risk factor risk reduction SARS-CoV-2 SARS-COV-2 infection secondary hemophagocytic lymphohistiocytosis serine protease sHLH Side effect significantly simple syndrome therapy TMPRSS2 Transmission treated Treatment Venous Thromboembolism viral infection vulnerable patients with COVID-19 World Health Organization [DOI] 10.3390/cancers12113316 PMC 바로가기 [Article Type] Review
The effects of allium sativum on immunity within the scope of COVID-19 infection코로나19 감염 범위 내에서 부추속이 면역력에 미치는 영향Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 치료기술, [키워드] abnormality activated active against Acute respiratory infection adipose Adipose tissue Allium allium sativum antiinflammatory antimicrobial antiviral efficiency appear Appetite Asymptomatic disease boost characteristic Compound Concentration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Cytokines decrease Decreased demonstrated dry cough dysfunction Dyspnea Effect expression fatigue Features functional functional food Garlic Gustatory helper helper T cells immune system immune system cell immune system cells Immune system dysfunction Immunity immunological immunomodulatory infected with SARS-CoV-2 Infection Leptin loss of appetite macrophages manifestation Manifestations Monocytes monocytes/macrophage monocytes/macrophages myalgia natural Natural killer cells olfactory parameters patients with COVID-19 prevalent preventive measure proinflammatory Proinflammatory cytokine proinflammatory cytokines Protein protein kinase protozoan parasites receptor regulatory T cells repress SARS-CoV-2 virus secretion severity suggested suppressed Symptom Symptoms T cells T lymphocytes tissue virus [DOI] 10.1016/j.mehy.2020.109934 PMC 바로가기 [Article Type] Article