Non-COVID-19 patients in times of pandemic: Emergency department visits, hospitalizations and cause-specific mortality in Northern ItalyResearch Article Published on 2021-03-222022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adjust all age group Care cause-specific mortality caused conducted consequence COVID-19 COVID-19 pandemic death Department described Diagnosis Diseases driven by dropped early phase Emergency emergency department Endocrine Endocrine diseases groups healthcare healthcare service Healthcare system Hospitalization hospitalizations increase in Italian Italy lockdown Mortality neoplasm Neoplasms non-COVID-19 patient Non-COVID-19 patients pandemic Patient recorded reduced reduction retrospective severity significant increase Weekly [DOI] 10.1371/journal.pone.0248995 PMC 바로가기 [Article Type] Research Article
Evolution of Pathology Patterns in Persons Who Died From COVID-19 in Italy: A National Study Based on Death CertificatesMedicine Published on 2021-03-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age Care cause of death Certificate changed circulation coded Comorbidities Comorbidity complex Complication coronavirus disease COVID-19 death death certificate Deceased defined determine diabete Diagnosis died disease epidemic wave Factor Frequency health system hospitals hypertensive ICD individual ischemic heart disease Italy knowledge less Mortality much lower neoplasm Older Pathologies Patient patients patients with COVID-19 pattern Person Pneumonia positive protocol provided reached reduction Respiratory failure resulting SARS-CoV-2 significantly higher Surveillance survival tested the epidemic Treatment virus [DOI] 10.3389/fmed.2021.645543 PMC 바로가기 [Article Type] Medicine
Association between Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) and Reduced Risk of Death in COVID-19 Patients: A Retrospective Cohort StudyArticle Published on 2021-03-072022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] 350 patient acid age amlodipine Belgium chronic chronic cardiac disease Comorbidity COVID-19 COVID-19 mortality curative treatment Deceased diabete discharged effective females functional functional inhibitors of acid sphingomyelinase (FIASMAs), COVID-19 hospital hypertension In-hospital In-hospital death in-hospital mortality in-patient In-patients inhibitor laboratory-confirmed long-term treatment males medication Mortality multivariable multivariate logistic regression neoplasm obesity Odds ratio Older age outcome participant patients died Prevalence reported retrospective cohort study risk factor SARS-CoV-2 significantly sphingomyelinase Treatment [DOI] 10.3390/ph14030226 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Is a Culprit for Some, but Not All Acute Ischemic Strokes: A Report from the Multinational COVID-19 Stroke Study GroupArticle Published on 2021-03-012022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval addition AIS Atherosclerosis Atrial fibrillation cerebrovascular disorders clinical risk cluster analysis Clustering Cohort cohort of patient cohorts of patient Comorbidities Comorbidity country COVID-19 criteria dataset demonstrated explained Frequency group healthy Hierarchical incidence infected patient investigated Ischemic ischemic heart disease large vessel literature review Logistic regression Machine learning algorithms majority men multicenter neoplasm Odds ratio pandemic Patient patients Prospective Study recorded report reported risk Risk factors SARS-CoV-2 SARS-CoV-2 infected patient Spectral stroke subgroup subsequent suffered suggested thrombotic event Vascular [DOI] 10.3390/jcm10050931 PMC 바로가기 [Article Type] Article
Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasmLetter Published on 2021-02-122022-10-04 Journal: Leukemia [Category] MERS, SARS, 유전자 메커니즘, [키워드] COVID-19 infection Disease-free survival Epidemiology Myeloproliferative disease National neoplasm Patient reported Result Risk factors [DOI] 10.1038/s41375-021-01143-2 PMC 바로가기 [Article Type] Letter
Double-blind, randomized, controlled, trial to assess the efficacy of allogenic mesenchymal stromal cells in patients with acute respiratory distress syndrome due to COVID-19 (COVID-AT): A structured summary of a study protocol for a randomised controlled trialCOVID-19(COVID-AT)로 인한 급성 호흡 곤란 증후군 환자에서 동종 간엽 기질 세포의 효능을 평가하기 위한 이중 맹검, 무작위, 대조 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-062022-09-10 Journal: Trials [Category] MERS, 바이오마커, 임상, 치료제, [키워드] 1:1 24 hours 7-point ordinal scale acute respiratory distress acute respiratory distress syndrome Administered administration Admission Adult patient Adult patients Adverse Adverse drug reactions AEs age All trial participants all-cause mortality allergy Allogeneic ARDS assessment assigned baseline Biomarker blinded Blinding C-reactive protein carcinoma carcinoma in situ carried cellular chain change childbearing potential Chloroquine Clinical practice clinical status clinical trial coagulation test coagulation tests conducted Control control arm Course COVID COVID-19 CRF criteria CT scan cumulative incidence current Cytokines D-dimer Day death described determined by Diagnosis disease dissemination double-blind drug Duration ECMO Efficacy Efficacy and safety element eligible End endpoints enrolment EudraCT evaluate evaluate the effect event exclusion criteria Extracorporeal extracorporeal membrane oxygenation failure ferritin fibrosis FiO2 form GRADE grade 3 greater Haemodialysis handling hemofiltration history hospital Hospitalization hydroxy ICU ICU admission IMPROVE include inclusion criteria Informed consent intravenous Intravenous administration intravenous dose intubation Invasive mechanical ventilation invasive ventilation investigational medicinal product involved laboratory confirmation laboratory-confirmed SARS-CoV-2 infection lactation LDH less Level Local Lopinavir Lopinavir/ritonavir lung disorder lymphocyte marker Mechanical mechanical ventilation Medicine Medicines Mesenchymal stromal cells moderate to severe Mortality MSC negative pregnancy test neoplasm neutrophil neutrophil counts Non-invasive number objective occur off-label opinion Ordinal Scale organ oropharyngeal swab oropharyngeal swabs Other outcome oxygen oxygen saturation Oxygen therapy PaO2 PaO2/FiO2 ratio parameters participant Patient PCR percentage Placebo polymerase chain reaction Pregnancy primary endpoint product Production profile progression protocol Pulmonary embolism pulmonary fibrosis Pulmonary function tests randomised randomised controlled trial randomization Randomized Randomly Rapid antigen tests reaction receive recruitment Registered Remdesivir report respiratory Respiratory distress syndrome Resuscitation Ritonavir SAEs Sample size SARS-COV-2 infection secondary Secondary endpoints Sequential Organ Failure Assessment Serious Adverse Events SOFA Spain specificity specimen Sponsor Standard of care status stromal cell stromal cells Study protocol subpopulations supplemental oxygen supplementary material syndrome the cell the disease the patient the primary endpoint the WHO time Tocilizumab Tolerability Treatment treatment arm treatment for COVID-19 treatment group Treatment protocol Trial trial participant Trial registration unit website women worldwide pandemic written consent [DOI] 10.1186/s13063-020-04964-1 PMC 바로가기 [Article Type] Letter
Aeromedical retrieval diagnostic trends during a period of Coronavirus 2019 lockdownObservational Study Published on 2020-12-012022-10-05 Journal: Internal medicine journal [Category] 임상, [키워드] 95% CI 95% confidence interval aeromedical cardiovascular Characteristics Cohort condition conditions coronavirus COVID-19 decrease diagnostic disease Endocrine female groups increase increase in increases in interquartile range lockdown majority male median age metabolic disease neoplasm Odds ratio pandemic Patient reduction in Respiratory system resulting retrospective rural and remote. social isolation [DOI] 10.1111/imj.15091 PMC 바로가기 [Article Type] Observational Study
Outcomes of COVID-19 Patients under Cytotoxic Cancer Chemotherapy in BrazilArticle Published on 2020-11-242022-10-31 Journal: Cancers [Category] COVID-19, [키워드] 95% CI 95% confidence interval analyzed baseline being Brazil cancer patient Chemotherapy Comorbidity COVID-19 COVID-19 cases cytotoxic died drug drug therapy evaluate exploratory Factors hematologic hematological increase increase in increased mortality information inhibitor Mortality multivariate model neoplasm Neoplasms Odds ratio outcome palliative intent Patient patients performed Propensity score Protective receive retrospective Retrospective analysis risk Risk factors risk of death simple tested Treatment variable with COVID-19 [DOI] 10.3390/cancers12123490 PMC 바로가기 [Article Type] Article
Impact of the First Wave of COVID-19 on Pediatric Oncology and Hematology: A Report from the French Society of Pediatric OncologyArticle Published on 2020-11-172022-10-31 Journal: Cancers [Category] COVID-19, [키워드] abnormality age analyzed Cancer Chemotherapy Child children conditions coronavirus disease cough COVID-19 COVID-19 diagnosis COVID-19 in patient diagnosed with COVID-19 Diagnosis died enrolled Evolution female Fever FIVE French Hematological malignancy Hospitalization HSCT identify Impact initiated intensive care medical record Most patient neoplasm oncology oxygen Patient patients pediatric radiological finding recommendations report required rhinorrhea risk SARS-CoV-2 severe COVID-19 simple Society solid tumor Stem cell transplantation Symptoms the disease the patient treated Wave [DOI] 10.3390/cancers12113398 PMC 바로가기 [Article Type] Article
Efficacy of influenza vaccine (Fluvax) in cancer patients on treatment: a prospective single arm, open-label studyClinical Trial Published on 2020-11-012023-06-23 Journal: Supportive Care in Cancer [Category] 신종인플루엔자, [키워드] Anti-neoplastic agents drug therapy Flu vaccines influenza vaccines neoplasm Treatment outcome [DOI] 10.1007/s00520-020-05384-2 [Article Type] Clinical Trial