Development of the DNA-based biosensors for high performance in detection of molecular biomarkers: More rapid, sensitive, and universal분자 바이오마커의 고성능 검출을 위한 DNA 기반 바이오센서 개발: 보다 신속하고 민감하며 보편적Review Published on 2022-02-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, 치료제, [키워드] Analytical chemistry antibodies applied biochemical Biology Biomarker Biomarkers caused Corona COVID-19 development Diagnosis Disease diagnosis DNA nanotechnology DNA-Based biosensors early diagnosis Enzymes example help High performance in vitro in vivo Infection introduced molecular Molecular biomarkers. molecules nucleic acid nucleic acids Numerous physiological platform probe producing Research SARS-CoV-2 specificity stability target targets the disease virus Virus Disease [DOI] 10.1016/j.bios.2021.113739 PMC 바로가기 [Article Type] Review
COVID-19-associated necrotizing encephalopathy presenting without active respiratory symptoms: a case report with histopathology활동성 호흡기 증상이 없는 코로나19 관련 괴사성 뇌병증: 조직병리학 증례 보고Case Reports Published on 2022-02-012022-09-11 Journal: Journal of Neurovirology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Aphasia Atypical Case report cerebrospinal fluid characteristic coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 described detect diagnosed Diagnosis diagnostic Encephalopathy etiologies exclusion expressive expressive aphasia feature hemorrhage high-dose methylprednisolone Histopathology Infection Inflammation lesion Methylprednisolone Mild MRI Necrosis neutrophilic Next-generation sequencing nucleic acids outcome pathogenic Patient perivascular pleocytosis Presence presenting respiratory symptoms SARS-CoV-2 secondary to serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 small vessel Symptoms treated Vasculitis viral respiratory [DOI] 10.1007/s13365-021-01042-3 PMC 바로가기 [Article Type] Case Reports
A fast and cheap in-house magnetic bead RNA extraction method for COVID-19 diagnosis코로나19 진단을 위한 빠르고 저렴한 자체 자기 비드 RNA 추출 방법Article Published on 2022-02-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition affecting automated COVID-19 COVID-19 diagnosis COVID-19 test cycle extraction FIVE genetic material gold gold standard high correlation house magnetic bead Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nasopharyngeal swabs nucleic acid nucleic acids pandemic platform positive protocol public health purification qPCR quantitative PCR Rapid reagents reduced Reverse transcription quantitative PCR RNA RNA extraction RNA extraction kits RT-qPCR SARS-CoV-2 SARS-CoV-2 detection the mean virus detection [DOI] 10.1016/j.jviromet.2021.114414 PMC 바로가기 [Article Type] Article
Aptamers—Diagnostic and Therapeutic Solution in SARS-CoV-2앱타머 - SARS-CoV-2의 진단 및 치료 솔루션Review Published on 2022-01-262022-09-10 Journal: International Journal of Molecular Sciences [Category] SARS, 진단, 치료기술, [키워드] acting affinity aptamer Aptamers aptasensors binding can be used candidate carrier carriers changes chemiluminescence coronavirus COVID-19 COVID-19 disease detect diagnosis of SARS-CoV-2 diagnostic DNA Early detection effective global public health Health Service Health services Infection nucleic acids point-of-care Protein reading SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus selected solution specificity test result the SARS-CoV-2 the SARS-CoV-2 virus therapeutic treat Treatment treatment of COVID-19 Viral protein Viral proteins [DOI] 10.3390/ijms23031412 PMC 바로가기 [Article Type] Review
ERDRP-0519 inhibits feline coronavirus in vitroResearch Published on 2022-01-252022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] Antiviral antiviral drug antiviral efficacy cat caused Cell culture cells complementary coronavirus CoV CoVs CrFK disease dose-dependent manner effective ERDRP-0519 evaluated Feline coronavirus (FCoV) Feline infectious peritonitis Feline infectious peritonitis (FIP) in vitro in vivo inhibit inhibited inhibitor logarithm nucleic acids pathogen polymerase quantification Replication Result significantly supplementary material Treatment Vaccine Viral load Viral RNA virulent virus was reduced [DOI] 10.1186/s12917-022-03153-3 PMC 바로가기 [Article Type] Research
An international, interlaboratory ring trial confirms the feasibility of an extraction-less “direct” RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples국제적, 간사 링 시험은 임상 샘플에서 SARS-COV-2 RNA의 신뢰할 수있는 검출을위한 추출없는 "직접"RT-QPCR 방법의 타당성을 확인합니다.Research Article Published on 2022-01-132022-09-10 Journal: PLoS ONE [Category] 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Aliquots applied Chain Reaction charcoal clinical sample clinical samples collected Concordance coronavirus coronavirus disease COVID-19 Cycle threshold values equipment extraction feasibility feasible generate guanidine house inhibit International Laboratory limitation nasopharyngeal Nasopharyngeal samples nucleic acid nucleic acids pandemic Patient PCR reaction performed pharyngeal polymerase chain polymerase chain reaction positive protocol provided purified quantitative polymerase chain reaction reagents resource respiratory reverse transcription RT-PCR RT-PCR assay RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus Spread Transcription translated Trial Viral viral transport media [DOI] 10.1371/journal.pone.0261853 PMC 바로가기 [Article Type] Research Article
International Nonproprietary Names (INN) for novel vaccine substances: A matter of safety새로운 백신 물질에 대한 INN(International Nonproprietary Names): 안전성 문제Review Published on 2022-01-032022-09-11 Journal: Vaccine [Category] SARS, 변종, [키워드] applicability assigned Biological Biological Standardization Committee COVID-19 COVID-19 pandemic criteria ENhance exchange expert explain facilitate Health Organization inactivated information ingredient International Nonproprietary Names live-attenuated vaccine live-attenuated vaccines mRNA vaccines name novel Novel vaccine substances novel vaccines nucleic acid nucleic acids patient safety pharmacovigilance recipients Recombinant protein recombinant proteins Safe SARS-CoV-2 SARS-CoV-2 vaccine the WHO Traditional unique Vaccine Vaccines Viral vector vaccines virus variant virus variants WHO World Health Organization [DOI] 10.1016/j.vaccine.2021.11.054 PMC 바로가기 [Article Type] Review
Discrimination of non-infectious SARS-CoV-2 particles from fomites by viability RT-qPCR생존력 RT-qPCR에 의한 매개체에서 비감염성 SARS-CoV-2 입자 구별Article Published on 2022-01-012022-09-11 Journal: Environmental research [Category] SARS, 치료기술, [키워드] applied Cell culture chloride collected concerning contact with coronavirus Coronavirus 2019 COVID-19 damaged debate develop discrimination Economy epidemiological estimation evaluate false False-positive fomites heat helping Human inactivated initial initial assessment marker matter Measures non-infectious nucleic acid nucleic acids pandemic PCR amplification PEDV Platinum procedure protocol public health qPCR quantification reported researcher resulting risk RNA extraction RT-qPCR SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 stability Spread Suspension swabbing procedure through contact Transmission risk viability viability RT-qPCR viral capsid viral infectivity viruses [DOI] 10.1016/j.envres.2021.111831 PMC 바로가기 [Article Type] Article
A smartphone-based visual biosensor for CRISPR-Cas powered SARS-CoV-2 diagnosticsCRISPR-Cas 기반 SARS-CoV-2 진단을 위한 스마트폰 기반 시각 바이오센서Article Published on 2022-01-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggregation applied changes clinical clinical samples clinically color coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR CRISPR-Ca CRISPR-Cas12a cross-reactivity Degradation detect develop diagnostics evidenced eye gold Gold nanoparticle Gold nanoparticles imperative limit of detection nucleic acid nucleic acids pandemic positive provide provided pseudovirus pseudoviruses qPCR RNA robust SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 pseudoviruses selective single-stranded DNA Smartphone Smartphone-based diagnostics the SARS-CoV-2 transcribed triggered vectors Visual Visual biosensor. [DOI] 10.1016/j.bios.2021.113646 PMC 바로가기 [Article Type] Article
The Nanoparticle-Enabled Success of COVID-19 mRNA Vaccines and the Promise of Microneedle Platforms for Pandemic Vaccine Response코로나19 mRNA 백신의 나노입자 기반 성공과 전염병 백신 대응을 위한 마이크로니들 플랫폼의 약속Section B: Infectious Diseases: Pathogenesis, Immune Responses, Vaccines, Diagnostics, and the Broad Impact of Them on Society Published on 2022-01-012022-09-10 Journal: DNA and Cell Biology [Category] 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen antigenic antigens approved biomaterials biomaterials and pandemic readiness cargo Cell Community coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccines Critical critical mass Degradation disease effective effort Europe facilitate feature Health crisis immune responses Lipid management medical intervention Microneedle microneedle arrays for vaccination mRNA mRNA vaccine mRNA vaccines nanoparticles and COVID-19 vaccines nucleic acid nucleic acids Outbreaks pandemic Pathogens Perspective promise PROTECT Protective provided public health public health crisis reached readiness regions Research respiratory response SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Spike protein the United State the vaccine the vaccines translated Trigger triggers United States vaccination Vaccine Vaccines [DOI] 10.1089/dna.2021.0538 PMC 바로가기 [Article Type] Section B: Infectious Diseases: Pathogenesis, Immune Responses, Vaccines, Diagnostics, and the Broad Impact of Them on Society