Label-free duplex SAMDI-MS screen reveals novel SARS-CoV-2 3CLpro inhibitors라벨이 없는 이중 SAMDI-MS 화면은 새로운 SARS-CoV-2 3CLpro 억제제를 보여줍니다Article Published on 2022-04-012022-09-11 Journal: Antiviral Research [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro activities acute respiratory syndrome Analysis Anti-viral Antiviral compound Antiviral compounds assays biochemical assay cathepsin cathepsin L cellular cytotoxicity chymotrypsin completion coronavirus COVID-19 cysteine cysteine protease described dose response evaluated feature gold High-throughput screening Human rhinovirus inhibitor mass mass spectrometry matrix monolayer optimization protease Protease inhibitor Proteases required reveal rhinovirus rhinoviruses SARS-CoV-2 selective selectivity Severe acute respiratory syndrome small molecule specific inhibitor structure activity relationship therapeutic target [DOI] 10.1016/j.antiviral.2022.105279 PMC 바로가기 [Article Type] Article
Improvement of caffeic acid biotransformation into para-hydroxybenzoic acid by Candida albicans CI-24 via gamma irradiation and model-based optimizationArticle Published on 2022-04-012023-07-06 Journal: Biotechnology and applied biochemistry [Category] COVID19(2023년), [키워드] Biotransformation caffeic acid Candida albicans Mutation optimization response surface methodology. [DOI] 10.1002/bab.2124
Transcatheter aortic valve implantation during COVID-19 pandemic: An optimized model to relieve healthcare system overloadArticle Published on 2022-04-012023-07-07 Journal: International journal of cardiology [Category] COVID19(2023년), [키워드] COVID-19 logistics optimization outcomes TAVI. [DOI] 10.1016/j.ijcard.2022.01.038 PMC 바로가기
Machine Learning with Quantum Seagull Optimization Model for COVID-19 Chest X-Ray Image ClassificationCOVID-19 흉부 X선 이미지 분류를 위한 양자 갈매기 최적화 모델을 사용한 기계 학습Article Published on 2022-03-302022-09-11 Journal: Journal of Healthcare Engineering [Category] 치료기술, 치료제, [키워드] addition approaches artificial artificial intelligence automated carried chest radiology chest X-ray classification COVID-19 COVID-19 diagnosis CXR dataset deep learning detect diagnosis of COVID-19 diagnostic disease effective extreme help Image intelligence machine learning management means Model mortality rate optimization outcomes performed quantum Respiratory system Spread target virus were assessed X-ray [DOI] 10.1155/2022/6074538 PMC 바로가기 [Article Type] Article
Optimization and Application of a Multiplex Digital PCR Assay for the Detection of SARS-CoV-2 Variants of Concern in Belgian Influent Wastewater벨기에 유입 폐수에서 우려되는 SARS-CoV-2 변종 검출을 위한 다중 디지털 PCR 분석의 최적화 및 적용Article Published on 2022-03-152022-09-11 Journal: Viruses [Category] SARS, 변종, 치료기술, 치료제, [키워드] application applied approach B.1.1.7 B.1.351 B.1.617.2 Belgium Chain Reaction changes in complementary Concentration concern COVID-19 COVID-19 pandemic detect detection develop Digital digital polymerase chain reaction Epidemiology influent investigated limit of detection MONITOR multiplex Mutation N501Y National optimization PCR polymerase chain polymerase chain reaction proportion ranged SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 variant Spread strain Strains target variant variants variants of concern VoC wastewater Wastewater-based epidemiology wild-type [DOI] 10.3390/v14030610 PMC 바로가기 [Article Type] Article
Optimization of COVID-19 vaccination and the role of individuals with a high number of contacts: A model based approachResearch Article Published on 2022-03-082022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] approach average Brazil calibrated compose Contact country COVID-19 incidence COVID-19 pandemic COVID-19 vaccination death Effectiveness Evidence greater Health services hypothetical individual lack optimization Portugal recovered reduction in resource social isolation symptomatic vaccination Vaccination strategies [DOI] 10.1371/journal.pone.0262433 PMC 바로가기 [Article Type] Research Article
Bayesian-based optimized deep learning model to detect COVID-19 patients using chest X-ray image data흉부 X선 영상 데이터를 이용한 코로나19 환자 검출을 위한 베이지안 기반 최적화 딥러닝 모델Article Published on 2022-03-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] Accuracy Analysis artefact artificial artificial intelligence assist Bayesian Bayesian optimization changed chest X-ray Chest X-ray image Chest X-ray images CNN components Convolutional neural network coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical dataset deep deep learning detect domain domains Features globe Image image classification intelligence learning optimization provided recent Recognition Research Research question researchers shown suggested variety [DOI] 10.1016/j.compbiomed.2022.105213 PMC 바로가기 [Article Type] Article
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian OptimizationReview article Published on 2022-03-012022-10-05 Journal: Computers in biology and medicine [Category] SARS, 변종, 치료기술, [키워드] Accuracy addition Algorithm Algorithms applied artificial automatically Bayesian Bayesian optimization Chest CNN Computed tomography Convolutional neural networks coronavirus COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 test decision diagnosis of COVID-19 died feature FIVE highest Infection lung machine learning MCC Naive Baye negatively affected network Neural optimization outbreak performed Prevent problem quarantine Radiography RT-PCR test Spread support vector machine SVM the disease tree Wuhan X-ray [DOI] 10.1016/j.compbiomed.2022.105244 [Article Type] Review article
Optimization of an Inclusion Body-Based Production of the Influenza Virus Neuraminidase in Escherichia coliArticle Published on 2022-02-192023-06-06 Journal: Biomolecules [Category] 신종인플루엔자, [키워드] expression Inclusion body neuraminidase optimization Recombinant protein response surface methodology [DOI] 10.3390/biom12020331 PMC 바로가기 [Article Type] Article
Optimization of the SARS-CoV-2 ARTIC Network V4 Primers and Whole Genome Sequencing ProtocolMedicine Published on 2022-02-172022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Amplicon amplicon drop-offs amplified ARTIC Network ARTIC V4 average Beta characterized clinical sample Concentration correlation Delta delta variant Eta Genome genome coverage IMPROVE increase in instance optimization Oxford Nanopore Technology positive control positive controls primer Primers protocol released Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 sequencing SARS-CoV-2 variants sequenced statistically significant the SARS-CoV-2 V3 primer set variant Whole genome sequencing [DOI] 10.3389/fmed.2022.836728 PMC 바로가기 [Article Type] Medicine