Detection of SARS-CoV-2 by real-time PCR under challenging pre-analytical conditions reveals independence of swab media and cooling chain도전적인 사전 분석 조건 하에서 실시간 PCR에 의한 SARS-COV-2의 검출은 면봉 매체와 냉각 체인의 독립성을 나타냅니다.Article Published on 2021-06-302022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, [키워드] Accuracy Adenovirus Affect Care CDC choice condition detection determined by diagnosis of SARS-CoV-2 Diseases HBSS Health Health care human metapneumovirus immunology independent independent of Influenza influenza A Laboratory media Medical research medium métapneumovirus Microbiology Molecular biology other respiratory virus Other respiratory viruses PCR question Real-time PCR reliability Resilience respiratory respiratory specimens respiratory syncytial virus respiratory viruses reveal rhinovirus rising RT-PCR Saline SARS-CoV-2 SARS-CoV-2 testing specimen storage storage conditions Swab temperature Transport Transport media transport medium Universal UTM Viral Viral detection viral transport media viruses VTM [DOI] 10.1038/s41598-021-93028-8 PMC 바로가기 [Article Type] Article
Trends in respiratory virus circulation following COVID-19-targeted nonpharmaceutical interventions in Germany, January – September 2020: Analysis of national surveillance dataResearch Paper Published on 2021-06-072022-10-30 Journal: The Lancet Regional Health - Europe [Category] COVID-19, [키워드] Acute respiratory infection appear ARI children circulation collected Contact COVID-19 detection diagnostics driven by examined finding funding gastroenteritis Germany Influenza initial Ministry of Health National nonpharmaceutical intervention Nonpharmaceutical interventions NPI NPIs observation period other respiratory virus Patient population immunity reduce reduction reported respiratory tract specimen respiratory virus respiratory viruses rhinovirus Robert RT-PCR SARS-CoV-2 School sentinel Spread subsequent suppressed Surveillance surveillance data sustained Transmission trend upper virus viruses [DOI] 10.1016/j.lanepe.2021.100112 PMC 바로가기 [Article Type] Research Paper
Performance of the LIAISON ® SARS-CoV-2 Antigen Assay vs. SARS-CoV-2-RT-PCRArticle Published on 2021-05-262022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Antigen calculated clinical sample COVID-19 cross-reactivity cut-off cut-offs DiaSorin evaluate False positive LIAISON LIAISON® SARS-CoV-2 antigen assay lowering nasopharyngeal swab sample other respiratory virus PCR-negative PCR-positive performance performed polymerase chain positive reference method RT-PCR SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 RNA SARS-CoV-2 viral load sensitivity Sensitivity and specificity specificity TCID tested the SARS-CoV-2 [DOI] 10.3390/pathogens10060658 PMC 바로가기 [Article Type] Article
Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeqArticle Published on 2021-05-252022-10-04 Journal: Nature Communications [Category] SARS, 진단, [키워드] Amplicon Analysis can be used COVID-19 pandemic demonstrated detect diagnose diagnostic diagnostics gold standard Human rhinovirus Infection Laboratory MONITOR other respiratory infection other respiratory virus pandemic pathogenic agents Pathogens PCR-based techniques performed Quantitative RNA RNA sequencing robustness RT-PCR Saliva SARS-CoV-2 sensitivity Sequencing Spread unique viral infection viral spread virions virus [DOI] 10.1038/s41467-021-22664-5 PMC 바로가기 [Article Type] Article
Coinfections with Respiratory Pathogens among COVID-19 Patients in KoreaResearch Article Published on 2021-05-122022-10-31 Journal: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale [Category] COVID-19, [키워드] 229E acute respiratory syndrome Adenovirus Bacteria Coinfection coronavirus coronavirus disease COVID-19 COVID-19 patient diagnostic value enrolled influenza A investigated majority métapneumovirus Mycoplasma pneumoniae Nasopharyngeal swab NL63 NPs OC43 oropharyngeal swab other respiratory virus Patient patients with COVID-19 positive respiratory respiratory pathogen respiratory specimen respiratory syncytial virus respiratory virus restored rhinovirus SARS-CoV-2 specimen specimens sputum subject the patient virus with COVID-19 yielding [DOI] 10.1155/2021/6651045 PMC 바로가기 [Article Type] Research Article
Natural mucosal barriers and COVID-19 in children어린이의 자연 점막 장벽과 COVID-19Clinical Medicine Published on 2021-05-102022-09-10 Journal: JCI Insight [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Adults Albert Einstein angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 anti–SARS-CoV-2 IgG Award both groups cellular children clinical clinical outcomes college contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytokines died disease manifestation emergency department enzyme epithelial cell epithelial cells Eric Evidence evidence of expressed expression expression of gene Gene Expression IFN signaling IFN-α2 IFN-γ IgA IgG IL-1β IL-8 immune cells Infectious disease innate immune response Innate immunity IP-10 Medicine mucosal mucosal immune nasal fluid Nasopharyngeal swab nasopharyngeal swabs natural NIH NLRP3 inflammasome not differ other respiratory virus Other respiratory viruses outcomes oxygen Pathways PROTECT Protein quantified quantitative reverse-transcription PCR required respiratory respiratory viruses RNA sequencing robust SARS Coronavirus SARS coronavirus 2 SARS-CoV-2 SARS-CoV-2 viral severe disease supplemental oxygen TMPRSS2 total protein Viral viruses [DOI] 10.1172/jci.insight.148694 PMC 바로가기 [Article Type] Clinical Medicine
A Longitudinal Study of the Epidemiology of Seasonal Coronaviruses in an African Birth CohortOriginal Articles Published on 2021-05-022022-10-30 Journal: Journal of the Pediatric Infectious Diseases Socie [Category] COVID-19, [키워드] acute respiratory syndrome African age-matched control association Bacteria Birth Cape case-control study children Co-infection Cohort collected conducted coronavirus Coronavirus infection Coronaviruses Endemic enrolled Epidemiology event HCoV-NL63 hospitalizations Hospitalized human coronavirus infancy Infant infect Infection investigated longitudinal Lower respiratory tract Nasopharyngeal swab occurred offer other respiratory virus Pathogenesis PCR Pneumonia positive Respiratory pathogens Result risk factor seasonal South Africa Streptococcus pneumoniae Surveillance tested town [DOI] 10.1093/jpids/piaa168 PMC 바로가기 [Article Type] Original Articles
Broad respiratory testing to identify SARS-CoV-2 viral co-circulation and inform diagnostic stewardship in the COVID-19 pandemicSARS-CoV-2 바이러스 공동 순환을 식별하고 COVID-19 전염병의 진단 책임을 알리기 위한 광범위한 호흡기 검사Research Published on 2021-05-012022-09-01 Journal: Virology Journal [Category] SARS, 진단, 치료기술, 치료제, [키워드] Algorithm Canada clinical laboratories Co-infection collected coronavirus Coronavirus 229E, human Coronavirus NL63, human Coronavirus OC43, human Coronaviruses COVID-19 COVID-19 case COVID-19 pandemic cross-reactivity diagnostic Diagnostic stewardship Endemic Endemic coronaviruses exacerbated examined expected identify include increase Influenza Laboratory less multiplex multiplex testing other respiratory virus Other respiratory viruses Panel pathogen Pathogens Patient positive Prevalence public health Public health interventions reduce resources respiratory respiratory pathogen Respiratory pathogens respiratory specimen respiratory specimens respiratory symptoms respiratory virus respiratory viruses Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 testing SARS-CoV-2 viral significantly significantly lower specimen specimens strain Symptom symptomatic patient Symptomatic patients tested transition viruses while [DOI] 10.1186/s12985-021-01545-9 PMC 바로가기 [Article Type] Research
Containment of COVID-19 and reduction in healthcare-associated respiratory viral infections through a multi-tiered infection control strategy다단계 감염 관리 전략을 통한 COVID-19 억제 및 의료 관련 호흡기 바이러스 감염 감소Article Published on 2021-05-012022-09-11 Journal: Infection, disease & health [Category] SARS, 진단, 치료기술, [키워드] acquisition acute respiratory syndrome Admission Community Containment COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic decrease Drawing evaluated HCW HCWs healthcare Healthcare associated healthcare worker Healthcare workers hospital Improved infection control Infection prevention Inpatient Inpatients Isolation lifting measure mitigate nosocomial nosocomial spread Nosocomial transmission other respiratory virus Other respiratory viruses outbreak Pathogens Patient positive Prevention and control Rate reduce reduction in reflected respiratory respiratory viral respiratory viral infection respiratory viral infections respiratory viruses RVIs SARS-CoV-2 SARS-CoV2 Severe acute respiratory syndrome Singapore Spread Surveillance sustained symptomatic patient tested Transmission Viral viruses [DOI] 10.1016/j.idh.2020.11.004 PMC 바로가기 [Article Type] Article
Clinical and Immunological Factors That Distinguish COVID-19 From Pandemic Influenza A(H1N1)유행성 인플루엔자 A(H1N1)와 COVID-19를 구별하는 임상 및 면역학적 요인Clinical Trial Published on 2021-04-212022-09-12 Journal: Frontiers in Immunology [Category] MERS, 신종인플루엔자, 임상, 진단, [키워드] acute respiratory distress syndrome acute respiratory syndrome alveolar CCL11 CCL3 characterized clinical clinically coronavirus coronavirus disease COVID-19 COVID-19 cases COVID-19 pandemic cytokine levels demonstrated diagnostic Diseases dry cough Factor Frequency G-CSF Gastrointestinal symptom Health Hemisphere histological histopathological IFN-γ IL-10 IL-12 IL-13 IL-1ra IL-1β IL-4 IL-5 IL-6 immune factor Immune profile immune response immunological characteristics induce Inflammatory response Influenza Influenza A(H1N1) pdm09 interstitial Lung pathology Lungs other respiratory virus pandemic pandemic influenza patients patients with COVID-19 Pneumonia respiratory symptoms SARS-CoV-2 severe disease manifestation Th1 Th2 tissue injury TNF-α TSLP unique VEGF [DOI] 10.3389/fimmu.2021.593595 PMC 바로가기 [Article Type] Clinical Trial