Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity비복제 Toxoplasma gondii Uracil Auxotrophs에 의한 Rhoptry 및 Dense Granule Effector 단백질의 분비는 항종양 면역의 발달을 제어합니다Research Article Published on 2016-07-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogated activate activated acute infection Auxotroph auxotrophic mutants axis CD4 CD8 Cell Nucleus Cell signaling cellular signaling pathway cellular signaling pathways conjunction Control deleted Deletion dendritic cells Dense development effective effective therapy effector effector molecule effector molecules effector protein effector proteins function Granule GTPase GTPases Host host cell host cell nucleus host cell response Host immune response host immune responses host innate immunity host response host responses identify IFN-γ immune responses Immune suppression Immunity independent Infection interferon Invasion latent infection mammalian cell mechanism membrane mice mutant not affect nucleus ovarian cancer parasite pathway Pathways Protein required responses rhoptry Safe secreted secretion shown Signaling solid tumor solid tumors survival T cell T cells target therapeutic These data Toxoplasma gondii transcriptional Trigger Tumor tumor microenvironment tumors type I uracil vaccination vaccine strain virulence [DOI] 10.1371/journal.pgen.1006189 PMC 바로가기 [Article Type] Research Article
Efficacy of tumor-targetingSalmonella typhimuriumA1-R on nude mouse models of metastatic and disseminated human ovarian cancer전이성 및 전파성 인간 난소암의 누드 마우스 모델에서 종양 표적 Salmonella typhimurium A1-R의 효능journal-article Published on 2014-06-012024-07-31 Journal: Journal of Cellular Biochemistry [Category] 살모넬라증, [키워드] Bacteria GFP imaging nude mice ovarian cancer Salmonella Typhimurium tumor-targeting [DOI] 10.1002/jcb.24871 [Article Type] journal-article
The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcomeArticle Published on 2007-04-102023-08-29 Journal: British Journal of Cancer [Category] E형 간염, [키워드] Angiogenesis Apoptosis EphB4 ovarian cancer survival [DOI] 10.1038/sj.bjc.6603642 PMC 바로가기