Molecular Basis of the Therapeutical Potential of Clove ( Syzygium aromaticum L.) and Clues to Its Anti-COVID-19 Utility정향(Syzygiumaromaticum L.)의 치료 가능성에 대한 분자적 기초 및 항-COVID-19 유용성에 대한 단서Review Published on 2021-03-262022-09-10 Journal: Molecules [Category] 신약개발, 치료제, [키워드] Syzygium aromaticum affecting Anti-inflammatory anti-inflammatory properties Antithrombotic Antiviral Basis caused clove coronavirus coronavirus disease Coronavirus infections COVID-19 COVID-19 patient COVID-19 patients described disorders Drug discovery Drug repurposing Economy Effect effective Effects eugeniin eugenol feature Frame Health herbal medicine immunization immunostimulatory ingredient Medicine molecular natural compounds Other pandemic Pandemics phytochemicals Potential problem protocol respiratory SARS-CoV-2 SARS-COV-2 infection Syzygium therapeutic therapy treat [DOI] 10.3390/molecules26071880 PMC 바로가기 [Article Type] Review
Medicinal Plants, Phytochemicals, and Herbs to Combat Viral Pathogens Including SARS-CoV-2Review Published on 2021-03-222022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Antiviral antiviral activity antiviral agent Antiviral agents antiviral property antiviral therapy approach caused combat component coronavirus disease COVID-19 effective Evidence Health Herb Herbs Including inhibit mechanism medicinal plants pandemic patients with COVID-19 phytochemical phytochemicals plant recent Replication Research SARS-CoV-2 SARS-COV-2 infection shown Stage Treatment viral entry viral pathogens virus [DOI] 10.3390/molecules26061775 PMC 바로가기 [Article Type] Review
Natural Products from Medicinal Plants with Anti-Human Coronavirus ActivitiesReview Published on 2021-03-212022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] ACE2 activity acute respiratory syndrome Analysis Antiviral caused coronavirus COVID-19 Critical Ebola effective Enzyme inhibitors Infection information medicinal plants Mortality natural pandemic phytochemicals plant product reported SARS-CoV SARS-CoV-2 Scientific community Spread spread to therapeutic therapeutic agent Treatment viral infection virus Wuhan, China [DOI] 10.3390/molecules26061754 PMC 바로가기 [Article Type] Review
Structure-Based Virtual Screening Identifies Multiple Stable Binding Sites at the RecA Domains of SARS-CoV-2 Helicase EnzymeArticle Published on 2021-03-072022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] Analysis approach ATP AutoDock average binding affinity binding energy binding free energy binding site complexes Compound COVID-19 COVID-19 pandemic criteria Critical database demonstrated disease docking domain drug drug-likeness enzyme Helicase metabolism molecular dynamic simulation MPD3 Multiple Nilotinib non-toxic physicochemical phytochemicals plant predict Protein PubChem RecA regulate repeated RNA SARS-CoV-2 SARS-CoV-2 helicase Scientific community screened Screening screening process Simulation study Site Spread STABLE the SARS-CoV-2 therapeutic strategy triangular Virtual screening was performed ZINC database [DOI] 10.3390/molecules26051446 PMC 바로가기 [Article Type] Article
Antiviral and Immunomodulation Effects of ArtemisiaReview Published on 2021-02-272022-10-30 Journal: Medicina [Category] COVID-19, [키워드] Abstract acute respiratory syndrome Antiviral antiviral action Artemisia Artemisinin article Arts Asia Bacteria biological activities Chinese collected Combination Committee coronavirus database derivative drug Drug discovery drugs Effect Europe Google immunomodulation in viral Infection Inflammation insecticidal investigated manuscript material Medicine North America parasite pharmacological physiological Physiology phytochemicals Prize public health PubMed Central Research SARS-CoV-2 subject unique utility zone [DOI] 10.3390/medicina57030217 PMC 바로가기 [Article Type] Review
Flavonoids against the SARS-CoV-2 induced inflammatory stormReview Published on 2021-02-252023-06-15 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] MERS, SARS, [키워드] Anti-inflammatory effects COVID-19 Cytokine storm flavonoids immunomodulation Inflammation phytochemicals SARS-CoV-2 [DOI] 10.1016/j.biopha.2021.111430 PMC 바로가기 [Article Type] Review
The Potential Therapeutic Effect of RNA Interference and Natural Products on COVID-19: A Review of the Coronaviruses InfectionPharmacology Published on 2021-02-232022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome anticancer antioxidant antiviral activity cause China clinical complication Compound coronavirus Coronavirus infection coughing death determine drugs Effect expression Fever Genes Genetic immune system include Infection inhibiting Interference miRNA miRNAs Morphological natural natural products organ pandemic phytochemicals Pneumonia Potential product Replication reported respiratory infection review RNA RNA interference SARS-CoV-2 SARS-CoV-2 virus Shortness of breath shown siRNA siRNAs virus Wuhan [DOI] 10.3389/fphar.2021.616993 PMC 바로가기 [Article Type] Pharmacology
Potential Natural Products Against Respiratory Viruses: A Perspective to Develop Anti-COVID-19 MedicinesPharmacology Published on 2021-02-172022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 2019 novel coronavirus 2019-nCoV 3CLpro ACE2 addition Against against SARS-CoV Angelica Antiviral antiviral activity antiviral potential approach Bioactivity caused China complementary Compound contagious coronavirus Coronaviruses country CoV COVID-19 COVID-19 disease demonstrated Epidemiology exhibited glycyrrhizin group hesperetin highlight immune response Infection influenza A inhibitory activity literature review Medicine MERS metabolite mode of action morbidity and mortality MOST natural Novel coronavirus pandemic Perceived risk Perspective Phylogenetic phylogenetics phytochemicals PLPro Potential product Protein quercetin receptor recognize Research respiratory respiratory infectious disease respiratory virus SARS-CoV SARS-CoV-2 therapy these compound these compounds Transmission viral infections Viral pneumonia virus World Health Organization Wuhan [DOI] 10.3389/fphar.2020.586993 PMC 바로가기 [Article Type] Pharmacology
Health Benefits of Plant-Based Nutrition: Focus on Beans in Cardiometabolic DiseasesReview Published on 2021-02-052023-06-13 Journal: Nutrients [Category] MERS, [키워드] Bean CVD Endothelial dysfunction legumes obesity phytochemicals plant-based diet SCFA type-2 diabetes [DOI] 10.3390/nu13020519 PMC 바로가기 [Article Type] Review
Targeting Neurological Manifestations of Coronaviruses by Candidate Phytochemicals: A Mechanistic ApproachPharmacology Published on 2021-01-202022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome angiotensin-converting enzyme 2 candidate caused Central nervous system combating complex complications complications of COVID-19 conducted coronavirus Coronaviruses COVID-19 delirium dysregulated Efficacy Evidence homology introduced lack manifestation Manifestations mechanisms Middle East nervous system Neuroinflammation neurological neurological manifestations neurological sign NEUROLOGY neuronal neuronal mechanisms Novel coronavirus Pain pathophysiological mechanism pharmacological Pharmacology phytochemicals protease Proteins provided respiratory RNA-dependent RNA polymerase SARS-CoV SARS-CoV-2 Secondary Metabolite signaling pathways stroke targeting therapeutic agent therapeutic target Treatment Web of Science [DOI] 10.3389/fphar.2020.621099 PMC 바로가기 [Article Type] Pharmacology