Development and Characterization of Magnetic SARS-CoV-2 Peptide-Imprinted PolymersArticle Published on 2021-11-062022-10-30 Journal: Nanomaterials [Category] COVID-19, [키워드] affecting approach binding affinity binding energy characterization complex condition development Dopamine Efficiency epitope imprinting evaluated fragment imprinting functional global pandemic Interaction key factor magnetic imprinted particles Molecularly imprinted polymers monomer peptide peptide imprinting Polymer problem SARS-CoV-2 selective sequence surrogate imprinting variable viral spike protein viral surface virion virus virus imprinting was selected Zika virus [DOI] 10.3390/nano11112985 PMC 바로가기 [Article Type] Article
Novel Biorecognition Elements against Pathogens in the Design of State-of-the-Art DiagnosticsReview Published on 2021-10-262022-10-27 Journal: Biosensors [Category] COVID-19, [키워드] Administered Antibiotics antibodies antimicrobial Aptamers Bacteria bacteriophage biorecognition biosensor causative pathogen complex Conventional dependent on Diagnosis diagnostic diagnostics DNAzymes effective Effectiveness element Enzymes hospitalisation identify inaccessible include Infectious disease ligands Mortality Naturally novel nucleic acid Other Palindromic pathogen pathogen identification Pathogens peptide peptide nucleic acids peptides POC point-of-care Polymer Providing reliability selective Therapeutic strategies viruses [DOI] 10.3390/bios11110418 PMC 바로가기 [Article Type] Review
SARS-CoV-2 inhibition using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray항 바이러스 비강 스프레이로서 작용할 수있는 점막 흡착성, 양친 매성 키토산을 사용한 SARS-COV-2 억제Article Published on 2021-10-082022-08-31 Journal: Scientific Reports [Category] SARS, 치료기술, 치료제, [키워드] A549 ACE-2 receptor adverse effect Anti-viral binding Biomedical materials Brain Cell clinical testing Concentration controls Coronavirus infections Course COVID-19 COVID-19 pandemic detect dose dosed effective electrostatic epithelial cells expressing Good host cells human airway human airway epithelial human airway epithelial cells hypothesise Infection inhibit injected limit log mammalian mechanism mice nares nasal nasal epithelial cell open Polymer Practice Prevent preventive intervention Prophylactic RATs reduce respiratory respiratory droplet Respiratory droplets respiratory tract Safe SARS-CoV-2 Spread spread of COVID-19 statistical significance TCID transgenic mice Vero E6 Vero E6 cell VERO E6 cells Viral viral entry viral infection Viral load virus [DOI] 10.1038/s41598-021-99404-8 PMC 바로가기 [Article Type] Article
Effects of surface charge and environmental factors on the electrostatic interaction of fiber with virus-like particle: A case of coronavirusRegular Articles Published on 2021-10-072022-10-28 Journal: AIP Advances [Category] COVID-19, [키워드] Accuracy Acidic calculate coronavirus determine distribution Effect electric potential electrostatic electrostatic interaction environmental factor fiber homogeneous increase Interaction linear observé Polymer Respirator SARS-CoV-2 significantly treat virus [DOI] 10.1063/5.0065147 PMC 바로가기 [Article Type] Regular Articles
The promising use of nano-molecular imprinted templates for improved SARS-CoV-2 detection, drug delivery and research향상된 SARS-CoV-2 검출, 약물 전달 및 연구를 위한 나노 분자 각인 템플릿의 유망한 사용Review Published on 2021-10-062022-09-10 Journal: Journal of Nanobiotechnology [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] 2019 antigenic antigenic determinants Artificial cell receptors Bacteria binding site can be used complementary coronavirus coronavirus disease COVID-19 COVID-2019 determinant diagnostic diagnostics Disease diagnosis include investigated mammalian cell microorganism microorganisms Molecular imprinted polymers molecule Nanocarriers pandemic Pandemics peptide peptides Plastic antibody Polymer polymers Protein regenerative regenerative medicine Research SARS-CoV-2 detection shape target technique Template therapeutic Therapeutics tissue tissue engineering Treatment virus viruses [DOI] 10.1186/s12951-021-01032-x PMC 바로가기 [Article Type] Review
The virucidal effects of 405 nm visible light on SARS-CoV-2 and influenza A virusArticle Published on 2021-09-302022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, 신종인플루엔자, [키워드] absence absorbance Biological techniques caused cellular COVID-19 creating Degradation demonstrated DNA Effect expected functions fungicidal Health care hospital Human inactivation indicated Infectious disease influenza A virus lack less limit mechanism Microbiology Optics and photonics organism Polymer Porphyrin reactive oxygen specy respiratory pathogen Safe SARS-CoV-2 shown Support susceptibility viral inactivation virucidal viruses wavelength while [DOI] 10.1038/s41598-021-97797-0 PMC 바로가기 [Article Type] Article
Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19COVID-19에 대해 DNA 나노백신을 보호하고 전달하는 분리형 마이크로니들 패치Article Published on 2021-09-282022-09-11 Journal: ACS Nano [Category] SARS, 치료법, [키워드] adaptive Adaptive immunity administration Against coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine decrease decreases DNA DNA vaccine DNA vaccines feature IFN-γ IgG IL-2 immune immune adjuvant Immune cell immune cells immune responses Immunity immunization in vivo Intramuscular injection lymph nodes Microneedle nucleic acid nucleic acid vaccine nucleocapsid pandemic patch Polymer Protein room temperature separable microneedle. significantly increased storage T cell T cells temperature tissue treated vaccination Vaccine Vaccines virus [DOI] 10.1021/acsnano.1c03252 PMC 바로가기 [Article Type] Article
Fluoxetine hydrochloride loaded lipid polymer hybrid nanoparticles showed possible efficiency against SARS-CoV-2 infectionFluoxetine hydrochloride가 탑재된 지질 고분자 하이브리드 나노 입자는 SARS-CoV-2 감염에 대해 가능한 효율성을 보여주었습니다Article Published on 2021-09-252022-09-11 Journal: International journal of pharmaceutics [Category] SARS, 신약개발, [키워드] acute respiratory syndrome coronavirus Affect Anti-inflammatory anticoagulant effects antidepressant Antiviral approach approved drug binding energy cells cellular coronavirus COVID 19 COVID-19 COVID-19 pandemic disease drug Drug repurposing drugs Economy Efficiency encapsulation ENhance fibroblast Fluoxetine Fluoxetine hydrochloride global health Health Human hydrogen Hydrogen bond Interaction Lipid Lipid polymer hybrid lung management molecular docking molecular docking studies Molecular docking study optimization Paroxetine performed Polymer predict protease repurposing respiratory SARS-COV-2 infection SARS-CoV-2 main protease selective Serotonin serotonin reuptake inhibitor severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 SSRIs. suggested therapeutic activity Treatment zeta potential [DOI] 10.1016/j.ijpharm.2021.121023 PMC 바로가기 [Article Type] Article
Covalent functionalization of polypropylene filters with diazirine–photosensitizer conjugates producing visible light driven virus inactivating materialsArticle Published on 2021-09-242022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] Activation aliphatic Biomedical materials condition conjugate crosslinking expected filtration healthcare inactivated inactivation insertion intensity Materials for devices Mild oxidizing pathogen Personal protective equipment Photochemistry Polymer Polymer chemistry PPE preventing infection producing reported Respirator RNA virus SARS-CoV-2 SARS-CoV-2 pandemic Support surface chemistry virus was tested [DOI] 10.1038/s41598-021-98280-6 PMC 바로가기 [Article Type] Article
Trivalent Subunit Vaccine Candidates for COVID-19 and Their Delivery DevicesCOVID-19 및 그 전달 장치에 대한 3가 소단위 백신 후보Article Published on 2021-09-152022-09-11 Journal: Journal of the American Chemical Society [Category] SARS, 변종, 치료제, [키워드] administration antibody approach approaches arises bacteriophage bacteriophage Qβ candidate conserved COVID-19 COVID-19 pandemic COVID-19 vaccine delivery Device diligence disease distribution Efficacy epitope Epitopes Formulation highlight human cells immunization Infection injection mice monovalent mutant neutralize SARS-CoV neutralizing epitope neutralizing epitopes peptide peptide epitope peptide epitopes platform Polymer Protein rapid development of vaccines Receptor binding S protein SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 vaccine shown the SARS-CoV-2 thermal stability trivalent Vaccine vaccine candidate vaccine platform variants variants of concern Viral diseases virus Virus-like particle virus-like particles VLP VLPs VOCs [DOI] 10.1021/jacs.1c06600 PMC 바로가기 [Article Type] Article