Let It Out (LIO) study: protocol for a mixed-methods study to optimise the design and assess the feasibility of an online emotional disclosure-based intervention in UK hospicesPalliative Care Published on 2021-05-112022-10-28 Journal: BMJ Open [Category] Coronavirus, Fulltext, SARS, [키워드] Analysis approved baseline Care collected COVID-19 pandemic dissemination Efficacy emotional England Ethics ethics committee Evidence expression feasibility Final group include Intervention measure mental health multisite outcome measure Palliative care participant Participants Patient peer-reviewed physical primary outcome measure protocol psychiatry psychological health psychological support qualitative data qualitative research Quantitative receive recruitment review secondary Secondary objective social media platforms statistics & research methods Support unique University College London [DOI] 10.1136/bmjopen-2020-047135 PMC 바로가기 [Article Type] Palliative Care
Proteinuria changes in kidney disease patients with clinical remission during the COVID-19 pandemicResearch Article Published on 2021-04-232022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] age analyzed blood pressure Care change changes in Chronic kidney disease CKD clinical feature clinical variable Complete coronavirus disease COVID-19 COVID-19 pandemic evaluated female Immunosuppression independent variable inhibitor Kidney disease maintenance dose multivariable analyses Odds ratio outpatient clinic pandemic Patient patients patients treated primary outcome measure Protein Proteinuria RAASi receiving reduced reduction Result significant interaction Support Therapeutic approach therapy Tokyo university hospital variable was used [DOI] 10.1371/journal.pone.0250581 PMC 바로가기 [Article Type] Research Article
Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection The INTERCOVID Multinational Cohort StudyCOVID-19 감염 여부에 관계없이 임산부의 산모 및 신생아 이환율 및 사망률 INTERCOVID 다국적 코호트 연구Comparative Study Published on 2021-04-222022-09-12 Journal: JAMA Pediatrics [Category] MERS, SARS, 진단, [키워드] 95% CI adjusted Admission adverse outcomes age Alter association Breastfeeding Care clinician cohort study Complication component country COVID-19 COVID-19 diagnosis COVID-19 symptoms demographic characteristics Diagnosis enrolled evaluate exposure finding higher risk hospital discharge Importance increased risk increases in indicate indicated individual individuals individuals with COVID-19 information intensive care laboratory confirmation Maternal maternal age measure Model morbidity morbidity and mortality Mortality Neonatal Neonate Newborn objective occurred outcome overweight participant Point polymerase chain positive Pregnancy pregnant pregnant women Preterm birth preventive measures primary outcome measure radiological Relevance remained Result risk Secondary outcomes setting Severe infection Shortness of breath significantly higher tested took place with COVID-19 women [DOI] 10.1001/jamapediatrics.2021.1050 PMC 바로가기 [Article Type] Comparative Study
Clinical characteristics of hospitalized patients with false-negative severe acute respiratory coronavirus virus 2 (SARS-CoV-2) test resultsObservational Study Published on 2021-04-192022-10-04 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] 95% CI 95% confidence interval adjusted odds ratio age Ageusia Analysis Anosmia association Characteristics chest imaging clinical Clinical characteristics clinical variable collected Comorbidities Contact coronavirus disease COVID-19 defined demographics determine elevated lactate dehydrogenase false-negative feature help hospitalized patient initial Laboratory multivariable multivariable analysis negative test Observational cohort study Older Patient polymerase chain Positive test predict primary outcome measure regression analysis Respiratory Coronavirus retrospective SARS-CoV-2 SARS-CoV-2 test significantly subsequent symptom duration Symptoms tested virus vital signs was used [DOI] 10.1017/ice.2021.146 PMC 바로가기 [Article Type] Observational Study
How often and to what extent do admitted COVID-19 patients have signs of cardiac injury?Guideline Published on 2021-04-162022-10-30 Journal: Netherlands Heart Journal [Category] COVID-19, [키워드] 95% CI 95% confidence interval Admission benefit can be used cardiac troponin cause COVID-19 cTn defined deteriorate elevated High-risk patients hospital Hospital stay ICU ICU admission implication Inconclusive Injury intensive care management medication administration Mortality mortality rate myocardial injury outcome Patient primary outcome measure proportion Result risk risk stratification secondary outcome measure supplementary material upper reference limit was performed worse prognosis [DOI] 10.1007/s12471-021-01571-w PMC 바로가기 [Article Type] Guideline
Role of interferon therapy in severe COVID-19: the COVIFERON randomized controlled trial중증 COVID-19에서 인터페론 요법의 역할: COVIFERON 무작위 대조 시험Randomized Controlled Trial Published on 2021-04-132022-08-13 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 임상, 치료제, [키워드] 95% CI adverse events Arm assigned benefit Chest CT scans clinical Clinical improvement clinical seven-step ordinal scale ClinicalTrials.gov, NCT04343768 conducted control group Controlled trial CT scan defined discharge Effect Enrollment FIVE Hydroxychloroquine IFNs IFNα IFNβ IFNβ1a IFNβ1b improvement indicated individually-randomized injection intention-to-treat population interferon interferons intervention group laboratory-confirmed SARS-CoV-2 infection Lopinavir Lopinavir/ritonavir median Mortality NCT04343768 no significant difference no significant differences Open-label Ordinal Scale P-value Patient positive positive RT-PCR Previous studies previous study primary outcome measure randomization Randomized controlled trial Randomly reduction in Registration registration number Respiratory tract diseases Ritonavir role SARS-COV-2 infection Seven severely ill patient significant difference single dose subcutaneous injections therapeutic therapy time Trial Registration Number TTCI twice a day type 1 interferon type 1 interferons Viral viral infections [DOI] 10.1038/s41598-021-86859-y PMC 바로가기 [Article Type] Randomized Controlled Trial
Therapeutic respiratory and functional rehabilitation protocol for intensive care unit patients affected by COVID-19: a structured summary of a study protocol for a randomised controlled trialCOVID-19의 영향을 받는 중환자실 환자를 위한 치료 호흡 및 기능 재활 프로토콜: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-122022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 6-minute walk test activities activity Admission Adult patients affected age Agitation approved assessment balanced randomization blinded Blinding block blocks Borg both groups Care clinical status clinical trial Coma Comorbidities Comorbidity comparator conducted confidentiality cooperation COVID-19 criteria Critical Critical illness daily living Data collection defined discharge dissemination distribution of patient double-blind Douro Dyspnea Effect element eligible Endpoint evaluate evaluated evaluator exertion expected Follow-up for inclusion form functional functional capacity functional rehabilitation Glasgow coma scale group Handgrip strength test Health Health Service Health services Hospital stay Hospitalization Hospitalized hospitalized COVID-19 patients ICU incidence include independent intensive care intensive care unit Intervention intervention group life mechanical ventilation Medical Research Council Medicine Mobility Monday need for oxygen number Nurse nursing care objective occupational therapy occur outcome outcome measure outcomes oxygen Oxygen therapy participant Participants Patient per day Perceived physical Physical assessment physical rehabilitation Physiotherapist Physiotherapy Portugal positioning post-intensive care syndrome Potential Potential participants primary outcome measure progression protocol Quality of life question randomisation randomised randomised controlled trial randomization sequence Randomized Randomized controlled trial readmission reassurance receive recommendation recorded recruited referred to Registered registry rehabilitation rehabilitation exercises rehabilitation medicine respiratory respiratory insufficiency respiratory rehabilitation Respiratory system responsible Sample size Saturday scale Secondary objectives sequence Sex Society stability standard care Standard of care status strength test study group Study protocol subject suctioning supplementary material survey survival Test the patient therapy Tolerance treated Treatment Trial registration two groups verbal website [DOI] 10.1186/s13063-021-05210-y PMC 바로가기 [Article Type] Letter
Effect of Clear vs Standard Covered Masks on Communication With Patients During Surgical Clinic Encounters: A Randomized Clinical TrialRandomized Controlled Trial Published on 2021-04-012022-10-05 Journal: JAMA Surgery [Category] SARS, 임상, [키워드] analyzed assessment Care clinic clinical clinics communication consequence consumer Covered COVID-19 pandemic Effect elicit enrolled evaluate the effect examined greater group Health involved knowledge Mask New outcome Patient patient data primary outcome measure quantitative assessment question randomization randomized clinical trial recruited Standard surgeon surgical System the patient unlikely verbal wearing mask [DOI] 10.1001/jamasurg.2021.0836 PMC 바로가기 [Article Type] Randomized Controlled Trial
Mortality and pulmonary complications in patients undergoing upper extremity surgery at the peak of the SARS-CoV-2 pandemic in the UK: a national cohort studyObservational Study Published on 2021-04-012022-10-05 Journal: BMJ Quality & Safety [Category] 임상, [키워드] 30-Day mortality Admission anaesthesia Analysis carried clinician cohort study Complication enrolled evaluation methodology First wave hospital hospitalised impacts include management Mortality MOST multicentre National occurred pandemic Patient patients positive postoperative primary outcome measure pulmonary complication routine safety culture SARS-CoV-2 SARS-CoV-2 pneumonia SARS-CoV-2 testing screened secondary outcome standards of care surgery symptoms prior tested the SARS-CoV-2 upper limb [DOI] 10.1136/bmjqs-2020-012156 PMC 바로가기 [Article Type] Observational Study
Virtual Health Care for Community Management of Patients With COVID-19 in Australia: Observational Cohort Study호주의 COVID-19 환자 커뮤니티 관리를 위한 가상 의료: 관찰 코호트 연구Original Paper Published on 2021-03-092022-09-12 Journal: Journal of Medical Internet Research [Category] SARS, 진단, [키워드] Admission Blood oxygen saturation Care Combination Community Community Management conducted COVID-19 COVID-19 pandemic death diagnosed Digital health discharged emergency department enrolled Escalation had no Health Health care Health care program health information Health Service Health services hospital Hospital admission hospital admission rate implementation informatics management median median age Most patients objective Observational cohort study oxygen pandemic Patient patients with COVID-19 prevalent primary outcome measure Primary outcome measures Pulse rate registered nurse remote monitoring Result Safe self-isolate shift skin skin temperature Support telehealth Telemedicine temperature the median the patient virtual health care were recorded [DOI] 10.2196/21064 PMC 바로가기 [Article Type] Original Paper