protective immunity – Page 6 – Communicable Diseases Research

IL-17 and IL-17-producing cells in protection versus pathology

Reviews

Published on 2022-07-052022-10-05
Journal: Nature reviews. Immunology [Category] 치료제,

Protection of hamsters challenged with SARS-CoV-2 after two doses of MVC-COV1901 vaccine followed by a single intranasal booster with nanoemulsion adjuvanted S-2P vaccine

MVC-COV1901 백신 2회 접종 후 SARS-CoV-2에 감염된 햄스터 보호 및 나노에멀젼 보조제 S-2P 백신이 포함된 단일 비강 내 부스터

Article

Published on 2022-07-052022-09-11
Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] alum booster booster vaccination country COVID-19 COVID-19 vaccine COVID-19 vaccines CpG1018 death Delta disease dose elicit followed by hamster Hospitalization Immunity immunization immunogenicity Infection intramuscular intranasal Lung pathology medical need mucosal offer omicron Pandemics Patient prefusion problem promote protection protective immunity protocol reduced regimen respiratory respiratory tracts resurgence robust S-2P SARS-CoV-2 SARS-CoV-2 spike severe COVID-19 severe disease solution Transmission vaccination Vaccine variants variants of SARS-CoV-2 Viral viral challenge viral clearance viral infection waning immunity weight loss were used
[DOI] 10.1038/s41598-022-15238-y PMC 바로가기 [Article Type] Article

Non-glycosylated SARS-CoV-2 RBD elicited a robust neutralizing antibody response in mice

글리코실화되지 않은 SARS-CoV-2 RBD는 마우스에서 강력한 중화 항체 반응을 유도했습니다

Article

Published on 2022-07-012022-09-12
Journal: Journal of Immunological Methods [Category] COVID19(2023년), MERS, SARS, 진단,

T cell responses against SARS-CoV-2 and its Omicron variant in a patient with B cell lymphoma after multiple doses of a COVID-19 mRNA vaccine

B 세포 림프종 환자에서 COVID-19 mRNA 백신을 여러 번 접종한 후 SARS-CoV-2 및 Omicron 변이체에 대한 T 세포 반응

Case Reports

Published on 2022-07-012022-09-11
Journal: Journal for immunotherapy of cancer [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Antibody Response B cell B cells CD4 CD8 COVID-19 COVID-19 infections develop disease severity dose expected healthy subject healthy subjects Hematologic malignancy hematologic neoplasms humoral Immune escape immune system immunology Immunosuppression implication initial Lymphocytes lymphoma Messenger RNA mRNA mRNA vaccine multiple dose Neoplasms omicron Patient Patients with cancer protective immunity response SARS-CoV-2 SARS-CoV-2 virus T cell T cell response T cells T-lymphocytes the patient the SARS-CoV-2 virus the vaccine vaccination Vaccination strategy Vaccine Vaccines variant Viral Viral transmission while
[DOI] 10.1136/jitc-2022-004953 PMC 바로가기 [Article Type] Case Reports

Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit proteins

SARS-CoV-2 감염에 대한 비용 효율적인 양 항체 기반 요법의 개발 및 스파이크 소단위 단백질에 대한 항체의 기여

Article

Published on 2022-07-012022-09-11
Journal: Antiviral Research [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

The Robustness of Cellular Immunity Determines the Fate of SARS-CoV-2 Infection

세포 면역의 견고함이 SARS-CoV-2 감염의 운명을 결정합니다

Review

Published on 2022-06-272022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제,

[키워드] addition Administered Analysis antibody secreting cells antiviral cytokine antiviral cytokines antiviral immunity antiviral response appearance approach autosomal recessive axis B cell booster dose breadth CD4+ CD4+ T cell CD8+ Cell cellular Cellular immune response cellular immunity component contribute coordinating correlated COVID-19 COVID-19 patient Critical cross-protection Cytokines cytotoxic lymphocytes cytotoxic T lymphocytes described disease Disease progression disease severity dysregulated evasion Evolution follicular functional Germinal center global pandemic greater helper T cells humoral IFN-γ immune protection immune system Immunity in some infected cells Infection infection control inflammatory cascade innate immune system killing knowledge long-lasting lymphocyte Lymphocytes magnitude memory modulating neutralizing antibody pathogenic inflammation phenotypic pro-inflammatory cytokine pro-inflammatory cytokines protective immunity reported responsible robustness SARS-CoV-2 SARS-CoV-2 virus secreting severe COVID-19 severity Stage stages T cell T cell response T cell responses T cells T helper cell T helper cells Tfh Tfh cells the SARS-CoV-2 virus thought TNF-α vaccination Vaccine viral replication X-linked
[DOI] 10.3389/fimmu.2022.904686 PMC 바로가기 [Article Type] Review

Contribution of low population immunity to the severe Omicron BA.2 outbreak in Hong Kong

홍콩의 심각한 Omicron BA.2 발병에 대한 낮은 인구 면역의 기여

Article

Published on 2022-06-242022-09-11
Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단,

Impact of Obesity on Vaccination to SARS-CoV-2

SARS-CoV-2에 대한 예방 접종에 대한 비만의 영향

Review

Published on 2022-06-202022-09-12
Journal: Frontiers in Endocrinology [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] acute respiratory syndrome Antibody titer BMI BMI - body mass index clinical trial conducted coronavirus CoV COVID COVID- 19 Effectiveness Efficacy elicited functional global public health healthy highlighting Human immune defect immune phenomenon immune response Impact implication individual induce Infection influenza vaccines influenza viruses information Johnson Johnson & Johnson Johnson & Moderna Moderna vaccine mounted obesity patients with obesity Pfizer Population protective effect protective immunity Research response SARS – CoV – 2 SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine severe SARS-CoV-2 subjects the healthy the vaccine Vaccine vaccine-induced antibody while
[DOI] 10.3389/fendo.2022.898810 PMC 바로가기 [Article Type] Review

Association of neutralizing breadth against SARS-CoV-2 with inoculation orders of heterologous prime-boost vaccines

Clinical and Translational Report

Published on 2022-06-092022-10-04
Journal: Med (New York, N.Y.) [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘,

[키워드] Abstract Affect Analysis Animal experiment antibody antibody cross-reactivity antibody response against association B.1.617.2 Booster vaccine breadth China circulating clinical evidence clinical observation Cohort Commission conducted confounders Context cost-efficient strategy COVID-19 vaccination COVID-19 vaccine Department development elicit Evidence finding foundation funding Health care worker healthcare worker Heterologous heterologous prime-boost heterologous vaccination heterologous vaccine homologous homologous or heterologous immune responses immunological analysis inactivated Influenza Innovation International Laboratory test mechanism Multivariable regression natural Neutralization antibody neutralization titer Neutralizing Neutralizing activity physician PNA Program protective immunity Pseudovirus neutralization assay recipient SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Science Serum Neutralization Shenzhen shown significantly lower subsequent suggested technology the United State the vaccine vaccination vaccination schedule Vaccine Vaccines variant variants veteran Virus neutralization Wuhan-Hu-1
[DOI] 10.1016/j.medj.2022.05.003 PMC 바로가기 [Article Type] Clinical and Translational Report

Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection

Article

Published on 2022-06-072022-10-04
Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, 치료법,

[키워드] acute respiratory syndrome benefit boost cellular clinical trial convalescent coronavirus coronavirus disease COVID-19 COVID-19 vaccine dose doses driving effective vaccine Efficacy evaluated geometric mean titer GMT greater Heterologous highlighting homologous human sera humoral immune response immune response immunize low dose lower airways mice mRNA mRNA vaccine NAb neutralizing antibody non-human primate non-human primates offer pandemic populations prefusion prime-boost regimen Protective protective immunity provided reduction regimen regimens replicate rhesus macaque rhesus macaques RNA vaccines Safe SAM SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine spike glycoprotein Spread T cell response tested Translational immunology vaccination Vaccine viral replication
[DOI] 10.1038/s41467-022-31005-z PMC 바로가기 [Article Type] Article