Impact of the Coronavirus Disease 2019 (COVID-19) Vaccine on Asymptomatic Infection Among Patients Undergoing Preprocedural COVID-19 Molecular Screening코로나바이러스 질병 2019(COVID-19) 백신이 시술 전 COVID-19 분자 스크리닝을 받는 환자의 무증상 감염에 미치는 영향Article Published on 2022-01-072022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] 95% CI acute respiratory syndrome adjusted Adjusted analysis age association Asymptomatic asymptomatic individual asymptomatic infection conducted coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine demonstrated dose Efficacy Emergency use authorization first dose Healthcare system hospital Impact Infection Local molecular molecular test mRNA mRNA-based vaccine Patient patients performed positive Primary outcome randomized trial reduced risk reduction in regions repeated reported Result retrospective cohort study risk SARS-CoV-2 SARS-COV-2 infection Screening screening test second dose Sex symptomatic Symptomatic patients the United State the vaccine vaccination Vaccine [DOI] 10.1093/cid/ciab229 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Reinfection Rate and Estimated Effectiveness of the Inactivated Whole Virion Vaccine BBV152 Against Reinfection Among Health Care Workers in New Delhi, IndiaSARS-CoV-2 재감염률 및 비활성화된 전체 Virion 백신 BBV152의 예상 효과Research Published on 2022-01-072022-09-10 Journal: JAMA Network Open [Category] 변종, [키워드] 95% CI adjusted adjusted hazard ratio Against age Analysis association Asymptomatic B.1.617.2 Care categories circulating Cohort cohort study Complete COVID-19 COVID-19 vaccine COVID-19 vaccines Cox proportional hazard Cox proportional hazards model Delta density diagnosed with COVID-19 dose Effectiveness elapsed Estimated event exposure finding follow-up period HCW HCWs Health care Health care worker health care workers HRs Importance inactivated incidence incidence density India infected with SARS-CoV-2 lower risk male measure New objective occurred Partial participant participated Point predominant proportional hazards model Protective Rate reduced risk Reinfection Relevance reported Result retrospective cohort study risk SARS-CoV-2 second dose setting symptomatic symptomatic and asymptomatic the SARS-CoV-2 vaccination vaccination schedule Vaccine variant variant of SARS-CoV-2 virion were infected worker [DOI] 10.1001/jamanetworkopen.2021.42210 PMC 바로가기 [Article Type] Research
Renin Angiotensin System Blockers and Risk of Mortality in Hypertensive Patients Hospitalized for COVID-19: An Italian RegistryArticle Published on 2022-01-062022-10-30 Journal: Journal of Cardiovascular Development and Disease [Category] COVID-19, [키워드] 95% confidence interval ACE inhibitors ACE2 adjusted Affect age analyzed angiotensin angiotensin receptor blocker Angiotensin receptor blockers angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors ARB blocker COVID-19 death disease exposure to FIVE Hospitalization Hospitalized hospitalized patient hospitals hypertensive patient in-hospital mortality indicate Italian lower risk Lymphocyte count males Mortality New coronavirus Occurrence Odds ratio oxygen saturation Patient patients died Primary outcome Prognostic markers Prognostic value Prospective Study protocol RAS reduce reduced risk reduction in registry Renin renin–angiotensin system retrospective risk SARS-CoV-2 severity significant effect significantly System tested treated with COVID-19 [DOI] 10.3390/jcdd9010015 PMC 바로가기 [Article Type] Article
Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19강력한 체액성 및 세포성 면역 반응 및 경증 COVID-19 무증상에서 최소 8개월 후 재감염 위험 낮음Article Published on 2022-01-012022-09-11 Journal: Journal of internal medicine [Category] SARS, 진단, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed anti-Spike IgG anti-spike IgG antibodies Anti-spike IgG antibody Asymptomatic asymptomatic to mild Cell Cellular immune response Chain Reaction Cohort coronavirus COVID-19 COVID-19 disease severity COVID-19 patient COVID-19 patients cumulative cumulative incidence detectable immune response Follow-up HCW healthcare worker hospitalized COVID-19 patients humoral Humoral response immune responses incidence Inclusion Infection initial investigated long-term immunity majority memory T memory T cell Mild PCR PCR-confirmed polymerase chain polymerase chain reaction positive positive individual protective effect reduced risk Reinfection remained respiratory response resulting risk SARS-CoV-2 SARS-COV-2 infection seroconverted seronegative seropositive severe acute respiratory syndrome Coronavirus Severe infection spike IgG Support T cell T cell responses vaccination [DOI] 10.1111/joim.13387 PMC 바로가기 [Article Type] Article
Impact of asthma on COVID-19 mortality in the United States: Evidence based on a meta-analysis천식이 미국에서 COVID-19 사망률에 미치는 영향: 메타 분석을 기반으로 한 증거Review Published on 2022-01-012022-09-11 Journal: International immunopharmacology [Category] SARS, 치료기술, [키워드] 95% CI 95% confidence interval age Analysis association Asthma coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality COVID-19 patient demonstrated Factor heterogeneity hospitalized patient hospitalized patients Impact indicated male Meta-analysis meta-regression Mortality Odds ratio Patient performed proportion Prospective Study publication bias Quantitative random-effects model reduced risk retrospective Retrospective study risk robustness Sample size sample sizes sensitivity analysis significantly statistically significant Study design Subgroup analyses subgroup analysis the United State The United States United States USA USA. was used [DOI] 10.1016/j.intimp.2021.108390 PMC 바로가기 [Article Type] Review
Association of the patterns of use of medications with mortality of COVID-19 infection: a hospital-based observational studyObservational Study Published on 2021-12-312022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI ACE inhibitor ACE2 ACE2 expression ACE2 receptor Affair Affect analysed angiotensin receptor blocker ARB ARBs association benefit Beta blockers Cell condition COVID-19 COVID-19 diagnosis Cox proportional hazard death diagnosis of COVID-19 dysregulation Epidemiology examined hospitalised patient identify increased risk indicated Infection Initiating Injury Logistic regression magnitude medical record medication medications morbidity Mortality Patient patients with COVID-19 PROTECT public health randomised clinical trial Randomised trial recent reduced risk Remdesivir Result reverse transcription PCR SARS-CoV-2 statistically significant Support survival therapeutic potential Treatment veteran virus were used with COVID-19 [DOI] 10.1136/bmjopen-2021-050051 PMC 바로가기 [Article Type] Observational Study
No neutralizing effect of pre-existing tick-borne encephalitis virus antibodies against severe acute respiratory syndrome coronavirus-2: a prospective healthcare worker study심각한 급성 호흡기 증후군 코로나 바이러스에 대한 기존의 진드기 매개 뇌염 바이러스 항체의 중화 효과 없음 : 전향 적 건강 관리 근로자 연구Article Published on 2021-12-172022-09-01 Journal: Scientific Reports [Category] SARS, 진단, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adjusted adjusted odds ratio antibodies antibody Antibody titer Antibody titers association baseline Cohort contribute Coronavirus-2 cross-protection Encephalitis explained exposure to Factors Follow-up HCW healthcare worker IgG immune activation immunization increase in knowledge Laboratory testing Neutralization assay Neutralizing neutralizing effect non-specific participant Pathogens protective role reduced risk residual confounding respiratory SARS-CoV-2 SARS-COV-2 infection Seroconversion serostatus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly higher suggested These data tick-borne encephalitis tick-borne encephalitis virus vaccination viral infection virus [DOI] 10.1038/s41598-021-03685-y PMC 바로가기 [Article Type] Article
Compassionate Use of Hydroxychloroquine in Clinical Practice for Patients With Mild to Severe COVID-19 in a French University Hospital프랑스 대학 병원의 경증 내지 중증 COVID-19 환자를 위한 임상 실습에서 하이드록시클로로퀸의 자비로운 사용Observational Study Published on 2021-12-062022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 신약개발, 임상, [키워드] addition Admission age Analysis analyzed Arterial hypertension Charlson Comorbidity Index clinical Comorbidity conducted confidence interval confounder confounders contraindication contraindications Controlled trial coronavirus disease Coronavirus disease 2019 COVID-19 death decision defined determine dosage effective French group hazard ratio help Hospitalized Hydroxychloroquine hypertension initial intensive care intensive care unit laboratory-confirmed Laboratory-confirmed COVID-19 medical history Mild National Early Warning Score NEWS2 Nonrandomized studies nonrandomized study not significantly different obesity outcome overall survival Patient patients treated Pneumonia Practice primary analysis primary endpoint Propensity score reduced risk reduction retrospective cohort study risk SARS-CoV-2 score severe COVID-19 severity Sex significantly Standard of care suggested symptom onset the mean the median therapeutic therapeutic agent Treatment treatment of COVID-19 university university hospital was performed Weighting with COVID-19 [DOI] 10.1093/cid/ciaa791 PMC 바로가기 [Article Type] Observational Study
Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study멘델식 무작위 배정 연구에서 지질 저하 약물과 COVID-19 결과의 연관성Research Article Published on 2021-12-062022-09-10 Journal: eLife [Category] 변종, 신약개발, 치료제, [키워드] 95% CI 95% confidence interval Analysis approach association associations benefit Blood calculate carried causal relationship caused cholesterol clinical trial confounding bias COVID-19 COVID-19 hospitalization COVID-19 pandemic death decrease drug drugs eLife estimates Evidence expression expression quantitative trait loci faster fat funding genetic instrument genetic instruments Genetic variant genetic variants Genome-wide association study higher risk HMGCR Hospitalization Hospitalized Human Hypothesis identify in viral infected with SARS-CoV-2 Infection infections LDL cholesterol Lipid lipid metabolism lipid-lowering drugs loci low-density Low-density lipoprotein mendelian randomization Mendelian randomization studies Mendelian randomization study metabolism Mortality MR study NPC1L1 Odds ratio outcome Patient PCSK9 positive protective effect Quantitative reduce reduced risk SARS-CoV-2 SARS-COV-2 infection severe disease SMR statins suggested susceptibility target gene Target genes treating COVID-19 university variable Viral viral infections virus were used with COVID-19 [DOI] 10.7554/eLife.73873 PMC 바로가기 [Article Type] Research Article
The association of COVID-19 antibody with in-hospital outcomes in COVID-19 infected patientsCOVID-19 감염 환자에서 COVID-19 항체와 병원 내 결과의 연관성Article Published on 2021-12-012022-09-12 Journal: Journal of medical virology [Category] Fulltext, MERS, 진단, [키워드] antibodies antibody Antibody test antibody test result association Characteristics confidential interval coronavirus disease COVID-19 COVID-19 antibody COVID-19 infected patient COVID-19 patients Hospitalization In-hospital in-hospital mortality Mortality negative test Odds ratio outcome Patient positive positive COVID-19 reduced reduced risk tested [DOI] 10.1002/jmv.27260 PMC 바로가기 [Article Type] Article