Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon ResolutionGenome Replication and Regulation of Viral Gene Expression Published on 2019-06-262022-10-30 Journal: Journal of Virology [Category] Coronavirus, MERS, [키워드] Analysis avian coronavirus Cell cellular changes in chick coding region Comparative complex conserved Coronaviruses data set Differential gene expression differentially expressed downstream Efficiency expand facilitated form Frame Gene Expression gene network generate Genome genomic RNA High-resolution host cell response host genes IBV IBV infection Improved include indicated Infection Infectious Bronchitis Virus isolates kidney Like Molecular biology mRNA transcript nucleocapsid occur ORF ORF4b pathogen pathogenic positive-sense quantification Replication Resolution ribosome profiling RNA genome RNA virus RNAseq Sequencing sgmRNA sgmRNA transcripts sgmRNAs Single nucleotide polymorphism single-stranded Spread strain Strains subgenomic mRNA Transcription translation translational Triplet upregulation Vaccination strategy vaccine candidate Variation viral RNA synthesis virus virus infection [DOI] 10.1128/JVI.00714-19 PMC 바로가기 [Article Type] Genome Replication and Regulation of Viral Gene Expression
Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARSResearch Published on 2005-05-112022-10-28 Journal: Respiratory Research [Category] Coronavirus, [키워드] abnormality acute phase acute respiratory syndrome alveolar cell alveolar macrophage Alveolar macrophages BALF Bronchoalveolar lavage Bronchoalveolar lavage fluid CD4/CD8 CD8 cell count cells clearance compared Computed tomography controls coronavirus correlated Course cytokine Cytokines described desquamation detected determine dysregulation Factor Fever High-resolution High-resolution CT HRCT hyaline membrane formation IL-6 IL-8 independent infiltration Inflammatory investigated lung Lung inflammation MCP-1 Microscopy mononuclear cell non-randomized occur Particle Patient patients persistence persistent Plasma cytokine profiles RANTES Resolution Result Retrospective analysis SARS SARS patient significantly subpopulations T lymphocyte T-cell therapy TNF-α [DOI] 10.1186/1465-9921-6-42 PMC 바로가기 [Article Type] Research