Respiratory illness – Page 6 – Communicable Diseases Research

“The possible implication of endothelin in the pathology of COVID-19-induced pulmonary hypertension”

Review article

Published on 2021-12-012022-10-05
Journal: Pulmonary pharmacology & therapeutics [Category] 바이오마커,

Fighting the pandemic with collaboration at heart: Report from cardiologists in a COVID-19-dedicated Portuguese intensive care unit

협력을 중심으로 전염병 퇴치: COVID-19 전담 포르투갈 집중 치료실의 심장 전문의의 보고서

Article

Published on 2021-12-012022-09-11
Journal: Revista portuguesa de cardiologia [Category] SARS, 치료기술,

[키워드] Adult patients age analyzed cardiac marker Cardiac markers Cardiologia Cardiology cardiovascular risk Care changed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 prognosis Cuidados intensivos Cuidados multidisciplinares de novo Decision making died discharged dysfunction dyslipidemia English Extra-corporeal membrane oxygenation Fighting followed by hypertension ICU intensive care male Manifestations mechanical ventilation membrane mobilization Multidisciplinary care myocardial injury N-terminal N-terminal pro-B-type natriuretic peptide Nova NT-proBNP one patient Oxigenação por membrana extracorporal pandemic Patient Patient care patients with COVID-19 pelo peptide pro-B-type natriuretic peptide report required Respiratory illness severe COVID-19 Spread Takotsubo the disease Vasopressor vasopressor support
[DOI] 10.1016/j.repce.2021.11.009 PMC 바로가기 [Article Type] Article

SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein

SARS-CoV-2는 스파이크 단백질을 통해 뇌 혈관주위세포의 면역 기능과 면역 기능을 완화합니다.

Article

Published on 2021-12-012022-09-11
Journal: Neurobiology of disease [Category] SARS, 유전자 메커니즘,

[키워드] accompanied accumulated ACE2 ACE2 expression acquisition Actin Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 assays binding Brain brain damage calcium cause caused cerebrovascular cerebrovascular disorders change characterized collagen Comorbidity contractile coronavirus disease coronavirus disease 19 Coronavirus-2 COVID-19 COVID-19 pathogenesis Cytokines deregulated develop disorder enzyme exacerbate Express expressing expression Fibronectin fluctuations function functional homolog host cell host cells human ACE2 Human brain hypoxia immune Immune cell immune function immune reaction impair infect infection with SARS-CoV-2 Inflammation inhibitory intranasal involved lipid peroxidation locus Macrophage mechanism mechanisms mice MIF Migration morphology Myofibrogenic transition nasal mucosa Neurological disorder Neurological disorders Neurovascular Neurovascular interface NF-κB NOTCH3 nuclear oxidative pericyte pericytes phenotypic pro-inflammatory cytokine pro-inflammatory cytokines promoted Protein Proteins provide reached reactivity receptor recognize Regulatory Respiratory illness S protein SARS-CoV-2 SARS-CoV-2 S protein SARS-CoV-2 S protein. Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus shown signaling pathway spike Stress therapeutic interventions transgenic mice translated transmembrane triggered Vascular viral spike was increased
[DOI] 10.1016/j.nbd.2021.105561 PMC 바로가기 [Article Type] Article

Absence of COVID-19 Disease Among Chronically Ventilated Nursing Home Patients

Observational Study

Published on 2021-12-012022-10-05
Journal: Journal of the American Medical Directors Associat [Category] SARS, 임상,

Plasma gp96 is a Novel Predictive Biomarker for Severe COVID-19

혈장 gp96은 심한 covid-19에 대한 새로운 예측 바이오 마커입니다.

Research Article

Published on 2021-11-242022-08-31
Journal: Microbiology Spectrum [Category] MERS, SARS, 바이오마커, 진단,

[키워드] acute respiratory illness analyzed coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID‐19 Critical DAMPs danger-associated molecular pattern danger-associated molecular patterns disease disease severity effective elevated evaluate Fever Heat shock heat shock protein heat shock proteins hospital Hospitalization Hsps IL-6 IMPROVE indicated Injury interleukin interleukin-6 less Mild monocyte Monocytes non-COVID-19 patient Non-COVID-19 patients novel outcome oxidative stress patients patients with COVID-19 plasma plasma concentration plasma concentrations plasma gp96 poor prognosis positively correlated predicted Predictive predictive biomarker prognostic biomarker Protein released respiratory Respiratory illness respiratory impairment respiratory symptoms severe coronavirus disease severe COVID-19 Severe patient severe patients significantly significantly higher Viral viral infection with COVID-19
[DOI] 10.1128/Spectrum.00597-21 PMC 바로가기 [Article Type] Research Article

Data mining methodology for response to hypertension symptomology—application to COVID-19-related pharmacovigilance

고혈압 증상에 대한 데이터 마이닝 방법론 - COVID-19 관련 약물 감시에 적용

Research Article

Published on 2021-11-232022-09-10
Journal: eLife [Category] MERS, SARS, 치료기술,

[키워드] acting acute respiratory illness ADE ADEs Adverse Affect affecting angiotensin Antihypertensive drug antihypertensive drugs Antithrombotic artificial intelligence association beraprost blockers blood pressure bosentan build calcium calcium channel calcium channel blockers candesartan Cluster Combination confounding factor confounding factors coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19-related pharmacovigilance data-driven methodology demographics disease Disease prevalence distribution doxazosin drug drugs effective endothelin receptor antagonist Endothelin receptor antagonists Epoprostenol evaluated exhibited Factor FDA FDA ADE database feature filtered Friedman test funding geometric geometric mean group had no hidden high risk highest hypertension Hypothesis incidence limit macitentan medication medications meta-analyses Meta-analysis methodology monotherapy Nifedipine None operator outcome Patient patients pharmacovigilance Potential potential therapy profile Pulmonary function pulmonary symptomology Quantitative randomized clinical trials Renin renin-angiotensin system reported Reporting respiratory Respiratory illness retrieved rilmenidine selected drug selected drugs selexipag shown Side effect significant difference significant differences significantly higher Sildenafil Stage Tadalafil Therapeutics therapy
[DOI] 10.7554/eLife.70734 PMC 바로가기 [Article Type] Research Article

Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients

Research Article

Published on 2021-11-232022-10-31
Journal: Future Microbiology [Category] COVID-19, MERS, SARS,

SARS-CoV-2 infection and replication in human gastric organoids

인간 위 오르가노이드에서의 SARS-CoV-2 감염 및 복제

Article

Published on 2021-11-162022-09-12
Journal: Nature Communications [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료제,

[키워드] adult stem cells antiviral response biopsy children COVID-19 described differentially expressed gene Differentially expressed genes differentiation facilitate fetal Gastrointestinal models Gastrointestinal symptom gastrointestinal symptoms generate in vitro model induce infect Infection infection with SARS-CoV-2 lack moderate observation Organoid organoids pediatric question raise replicate Replication Respiratory illness Respiratory system SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission significantly lower stomach susceptible the interferon transcriptomic analysis Transmission viral clearance viral infection viral replication viral shedding virus
[DOI] 10.1038/s41467-021-26762-2 PMC 바로가기 [Article Type] Article

Racial and ethnic inequities in occupational exposure across and between US cities

Article

Published on 2021-11-132022-10-29
Journal: SSM - Population Health [Category] COVID-19,

Interferon-α2 Auto-antibodies in Convalescent Plasma Therapy for COVID-19

COVID-19에 대한 회복기 혈장 요법의 인터페론-α2 자가항체

Original Article

Published on 2021-11-122022-09-10
Journal: Journal of Clinical Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제,

[키워드] age Analysis association Auto-antibodies auto-antibody Concentration condition convalescent plasma convalescent plasma treatment COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients determine disease severity Donor Effect ELISA healthy controls Human plasma ICU patient ICU Patients IFN-α2 interferon Interferon alpha longitudinal Longitudinal analyses Neutralization assay neutralized Neutralizing not neutralize Patient performed physiological plasma positive proportion proportions respiratory Respiratory illness respiratory illnesses respiratory tract Result risk SARS-CoV-2 sera serum Sex supplementary material survival tested transfer Viral viral clearance Viral load virological outcome
[DOI] 10.1007/s10875-021-01168-3 PMC 바로가기 [Article Type] Original Article