SARS-CoV-2 immunity – Page 6 – Communicable Diseases Research

Seroprevalence of SARS-CoV-2 IgG antibodies among health care workers prior to vaccine administration in Europe, the USA and East Asia: A systematic review and meta-analysis

Research Paper

Published on 2021-03-082022-10-31
Journal: EClinicalMedicine [Category] COVID-19,

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

경도 중등도 COVID-19에서 SARS-CoV-2에 대한 면역 반응의 진화

Article

Published on 2021-02-192022-09-12
Journal: Nature Communications [Category] MERS, 변종, 진단, 치료기술,

[키워드] accumulate Analysis antibody B cell CD4 CD4-positive T cells Cell change circulating Cohort cohort of patient convalescent Course COVID-19 follicular fraction Frequency greater IgG immune immune cell response immune cell responses immune response immune responses Immunity Immunological memory implication indicate Infection longitudinal Longitudinal analyses maintenance memory B memory B cell memory B cells natural infection Neutralising activity Neutralising antibody responses Neutralizing antibody response neutralizing antibody responses participant Patient population level Post-infection predict Protective Reinfection SARS-CoV-2 SARS-CoV-2 immunity SARS-COV-2 infection SARS-CoV-2 vaccine SARS-CoV-2 vaccines serological serum T cell titre Vaccine development viral infection
[DOI] 10.1038/s41467-021-21444-5 PMC 바로가기 [Article Type] Article

COVID-19 in Autoinflammatory Diseases with Immunosuppressive Treatment

Article

Published on 2021-02-052022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

Switched and unswitched memory B cells detected during SARS-CoV-2 convalescence correlate with limited symptom duration

SARS-CoV-2 회복기 동안 감지된 전환 및 전환되지 않은 메모리 B 세포는 제한된 증상 지속 기간과 상관 관계가 있습니다

Research Article

Published on 2021-01-282022-08-13
Journal: PLoS ONE [Category] Biochemistry, 진단, 치료기술,

[키워드] activated acute disease acute respiratory syndrome acute respiratory syndrome coronavirus antibody antibody-secreting plasmablasts B cell B cell response B cell responses B cell subsets causative agent CD24 CD27 characterized classical Clinical outcome composed convalescent Convalescent patients convalescent plasma treatment Coronavirus-2 correlated COVID-19 Critical disease Donor donors duration of symptom enrolled expansion Frequency health emergency identify IGD IgG1 IgM IgM response IgM responses memory memory B cell memory B cells pandemic Peripheral blood plasma antibody positive RBD Receptor binding domain remained respiratory Respiratory illness response responses SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 spike protein receptor binding domain seropositive subjects Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significant negative correlation significantly Spike protein subject subjects subset symptom duration the SARS-CoV-2 while
[DOI] 10.1371/journal.pone.0244855 PMC 바로가기 [Article Type] Research Article

A New SARS-CoV-2 Dual-Purpose Serology Test: Highly Accurate Infection Tracing and Neutralizing Antibody Response Detection

새로운 SARS-CoV-2 이중 목적 혈청 검사: 매우 정확한 감염 추적 및 중화 항체 반응 검출

Virology

Published on 2021-01-262022-09-10
Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술,

[키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin antibodies antibody coronavirus detect detection domain Donor eight ELISA expected Extracellular hACE2 human Angiotensin-converting enzyme individual Interaction less neutralization test neutralization tests Neutralizing Neutralizing antibodies New patients positive purified RBD receptor Receptor binding domain Reinfection respiratory response SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 immunity SARS-CoV-2 spike protein SARS-CoV-2 spike protein receptor binding domain serology serology test serology tests Spike protein Support Surveillance sVNT tracing vaccinated individual vaccinated individuals Vaccines virus neutralization test
[DOI] 10.1128/JCM.02438-20 PMC 바로가기 [Article Type] Virology

Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection

항체와 사이토카인 생산의 상호작용으로 CXCL13이 치명적인 SARS-CoV-2 감염의 잠재적인 신규 바이오마커로 밝혀짐

Research Article

Published on 2021-01-202022-09-10
Journal: mSphere [Category] 바이오마커, 진단, 치료법,

[키워드] Activation age Alpha Analysis analyzed anti-SARS-CoV-2 antibody antibodies antibody antibody level antibody levels Antigen antigens B cell Biomarker Blood blood type chemokine chemokine CXCL13 chemotactic marker chemotactic markers Course COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients COVID-19 virus CXCL13 cytokine Cytokine analysis cytokine response Cytokines develop disease disease severity elevated Eotaxin exhibited explain gamma interferon Germinal center healthy individuals help identify IFN-γ IL-12 IL-18 IL-2 IL-4 IL-6 IL-8 immune immune response immune system Immunity immunological Immunological response Increases increases in Infection information interferon interleukin interleukin 6 involved IP-10 knowledge lethal magnitude majority marker maturation MIP-1α Necrosis novel nucleocapsid outcomes Patient patient mortality patients who survived populations Potential produced Production proinflammatory Protein provide RANTES RBD Receptor binding domain S1 subunit SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 immunity SARS-CoV-2 pandemic SARS-CoV-2 patient SARS-CoV-2 patients severe COVID-19 Sex significant level specificity specimens systemic immune response TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha Variation Viral Viral proteins
[DOI] 10.1128/mSphere.01324-20 PMC 바로가기 [Article Type] Research Article

Dissecting strategies to tune the therapeutic potential of SARS-CoV-2–specific monoclonal antibody CR3022

SARS-CoV-2-특이적 단일클론항체 CR3022의 치료 가능성을 조정하기 위한 해부 전략

Research Article

Published on 2021-01-112022-09-10
Journal: JCI Insight [Category] 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration antibody Antigen coronavirus COVID-19 CR3022 Critical effort Epidemiology function functional functions globe hamsters highlighting IgG1 immune clearance immunology infected cell infected cells Infection Interaction lack mice monoclonal antibody mutations pathology respiratory SARS-CoV-2 SARS-CoV-2 immunity SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Spread susceptible therapeutic potential Therapeutics Treatment variant variants Viral viral replication virus weight loss
[DOI] 10.1172/jci.insight.143129 PMC 바로가기 [Article Type] Research Article

Validation and clinical evaluation of a SARS-CoV-2 surrogate virus neutralisation test (sVNT)

Research Article

Published on 2020-11-012022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS,

[키워드] analytical sensitivity anti-SARS-CoV-2 antibody biosafety can be used cell-based virus neutralisation assay clinical clinical evaluation clinical sensitivity collected COVID-19 described detect determine Diagnosis ELISA functional Immune status increase in independent infection assay natural infection neutralisation neutralisation assay neutralisation assays Neutralising Antibodies PCR-confirmed COVID-19 performed positive Pseudotyped viruses pseudovirus neutralisation assay Receptor binding domain SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 neutralising antibody sensitivity sera severity specificity surrogate virus neutralisation assay sVNT symptom onset titre vaccinated individual vaccination validation Virus neutralisation virus neutralising assay wild type
[DOI] 10.1080/22221751.2020.1835448 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients

Article

Published on 2020-10-212023-07-11
Journal: Journal of Clinical Microbiology [Category] SARS,

[키워드] ACE2 blocking assay COVID-19 functional antibodies SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 vaccine Serological tests
[DOI] 10.1128/JCM.01533-20 PMC 바로가기

SARS-CoV-2 Consensus-Sequence and Matching Overlapping Peptides Design for COVID19 Immune Studies and Vaccine Development

Article

Published on 2020-08-062022-10-28
Journal: Vaccines [Category] COVID-19,