serine 2 – Page 6 – Communicable Diseases Research

White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL/6 mice

Article

Published on 2021-08-022022-10-29
Journal: NPJ Science of Food [Category] COVID-19,

TRP channels in COVID-19 disease: Potential targets for prevention and treatment

Review article

Published on 2021-08-012022-10-05
Journal: Chemico-biological interactions [Category] 치료법,

The effect of environmental diesel exhaust pollution on SARS-CoV-2 infection: The mechanism of pulmonary ground glass opacity

SARS-CoV-2 감염에 대한 환경 디젤 배기 오염의 영향: 폐 유리 불투명도의 메커니즘

Review

Published on 2021-08-012022-09-11
Journal: Environmental toxicology and pharmacology [Category] 유전자 메커니즘,

[키워드] accompany ACE2 ACE2 receptors acute respiratory syndrome alveolar epithelial cell alveolar epithelial cells alveolar macrophage angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 atmospheric Chronic exposure complications component COVID-19 CT scan Cytokine storm diesel exhaust Diesel exhaust particles ENhance entry of SARS-CoV-2 enzyme epithelial cells exacerbate exposure to expression Extracellular matrix facilitate GGO Ground glass opacity ground-glass opacity growth increase increase in Increased indication Inflammation lung damage Macrophage mechanism Particle Particulate matter Probability proliferation protease Respiratory system risk SARS-CoV-2 SARS-COV-2 infection Serine serine 2 Severe Acute Respiratory Syndrome Corona Virus Severe acute respiratory syndrome corona virus-2 severe pneumonia Spread TGF-β1 TMPRSS2 Transforming transforming growth factor transforming growth factor-β1 transmembrane transmembrane protease serine 2
[DOI] 10.1016/j.etap.2021.103657 PMC 바로가기 [Article Type] Review

Do Anti-androgens Have Potential as Therapeutics for COVID-19?

항안드로겐이 COVID-19 치료제로 가능성이 있습니까?

Article

Published on 2021-08-012022-09-11
Journal: Endocrinology [Category] SARS, 유전자 메커니즘,

[키워드] ACE2 acting Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification androgen Androgen receptor androgens angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Anti-androgen anti-androgens attachment Cancer cells Cell cells characterized cleavage clinical trial coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity Deprivation exhibiting expression followed by Gender glycoprotein Hospitalization Hypothesis increase infect Infection limitation lung male men mitigate molecular mortality rate offer patients Perspective Potential Prostate cancer protease receptor Recognition reducing responsible SARS-CoV-2 Serine serine 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity Sex sex differences spike glycoprotein Spike protein susceptibility Testosterone Therapeutics therapy TMPRSS2 TMPRSS2 expression transmembrane transmembrane protein viral spike virus women
[DOI] 10.1210/endocr/bqab114 PMC 바로가기 [Article Type] Article

Profiling of Oral Microbiota and Cytokines in COVID-19 Patients

Microbiology

Published on 2021-07-302022-10-31
Journal: Frontiers in Microbiology [Category] COVID-19,

[키워드] 16S rRNA ACE2 acute respiratory syndrome Analysis angiotensin-converting enzyme 2 Area AUC automated Bacterial Biomarker clinics consortia Control controls coronavirus COVID-19 COVID-19 patients COVID-19 susceptibility Curve Cytokines demonstrated evidenced group highlighting immunoassays Inflammatory introduced local inflammation machine learning metagenomics microbiota (D064307) mucosa multiplex network analysis oral oral microbiota parameter Patient pilot study predict predominant Prevotella pro-inflammatory cytokine Profiling protease recent reduce Saliva SARS-CoV-2 secreted Sequencing serine 2 serum samples severe coronavirus disease Specy sputum subject subjects Symptoms TMPRSS2 Transcriptome transmembrane Transmission two group Viral RNA
[DOI] 10.3389/fmicb.2021.671813 PMC 바로가기 [Article Type] Microbiology

Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection

Review

Published on 2021-07-262022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19,

[키워드] “cytokine storm” ACE2 acid Activation acute respiratory syndrome addition alpha-lipoic acid alveolar cells Analysis anti-inflammatory effect antioxidant appear ARDS binding blood vessels cardiovascular cardiovascular comorbidity cardiovascular disease caused cellular entry Coagulopathy complex Complication contribute coronavirus Coronavirus disease 2019 COVID-19 COVID-19 complications COVID-19 infection Critical critical condition death distress distribution dysfunction endothelial Endothelial cell Endothelial dysfunction endothelial function Endothelium Evolution expressed global pandemic high risk homeostasis human Angiotensin-converting enzyme immune system IMPROVE independent induce infected with SARS-CoV-2 Infection Inflammation information insight interfere lung Mechanics mechanism microthrombi mitochondrial Mitochondrial function multiorgan failure Myocardial infarction nitric oxide oxidative stress pathology pathway Patient Perspective predominant Prognosis proinflammatory protease Protein reactive oxygen specy receptor redox status reduced reported Respiratory disease SARS-CoV-2 SARS-COV-2 infection serine 2 severe COVID-19 signaling pathways small intestine Spread stroke the S protein the SARS-CoV-2 therapeutic therapy thrombosis tissue TMPRSS2 transmembrane underlying diseases upregulation viral infection viral surface virus Wuhan, China
[DOI] 10.3390/ijms22157979 PMC 바로가기 [Article Type] Review

Animal Transmission of SARS-CoV-2 and the Welfare of Animals during the COVID-19 Pandemic

Review

Published on 2021-07-082022-10-28
Journal: Animals : an Open Access Journal from MDPI [Category] COVID-19,

Network-Based Analysis of Fatal Comorbidities of COVID-19 and Potential Therapeutics

COVID-19 및 잠재적 치료제의 치명적인 동반 질환에 대한 네트워크 기반 분석

Article

Published on 2021-07-012022-09-11
Journal: IEEE/ACM transactions on computational biology and [Category] SARS, 신약개발, 치료제,

[키워드] ACE2 acute lung injury acute respiratory distress acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aging angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 applied approach association Basigin BSG Cancer Cardiovascular disorders caused COL-3 Complication contagious contagious disease coronavirus COVID-19 Critical diabetes Diabetic diabetic complications disease downregulate drug Effect entinostat explain fatality Fatality rate Gene Expression host-pathogen interaction human proteins insulin investigated involved lung cancer Lung injury mocetinostat molecular basis network older patient older patients pathway Potential protease Protein protein-protein interaction RAGE random random walk respiratory distress SARS-CoV-2 SARS-CoV-2 proteins Serine serine 2 severe acute respiratory syndrome Coronavirus shown Signaling significantly significantly higher Therapeutics TMPRSS2 transmembrane transmembrane protease serine 2 viral invasion
[DOI] 10.1109/TCBB.2021.3075299 PMC 바로가기 [Article Type] Article

Replication Kinetics, Cell Tropism, and Associated Immune Responses in SARS-CoV-2- and H5N1 Virus-Infected Human Induced Pluripotent Stem Cell-Derived Neural Models

Research Article

Published on 2021-06-232022-10-30
Journal: mSphere [Category] COVID-19, MERS, SARS,

[키워드] accumulating ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 associated immune response Brain cell tropism cell type cells Central nervous system cerebrospinal fluid CNS contribute coronavirus COVID-19 COVID-19 patients Culture cultures disease Evidence expression H5N1 H5N1 influenza A H5N1 virus highly pathogenic hiPSC neurons Human Hypothesis IL-8 induced infect Infection influenza A virus Influenza virus interferon Invasion investigated Kinetics local immune response Model Neural Neurological complication Neurological complications Neuron neurons neurotropic neurotropism NPR1 olfactory Pathogenesis pluripotent stem cell protease replicated replication kinetics response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication serine 2 Spread STEM subsequent Support TMPRSS2 transmembrane triggered triggering tropism type III interferon variety virus virus replication virus spread
[DOI] 10.1128/mSphere.00270-21 PMC 바로가기 [Article Type] Research Article

Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19

SARS-CoV-2가 다른 방식으로 공격하는 이유는 무엇입니까? 숙주 유전적 요인은 COVID-19의 획득 또는 경과에 영향을 미칠 수 있습니다

Review

Published on 2021-06-012022-09-11
Journal: European journal of medical genetics [Category] SARS, 바이오마커, 변종, 유전자 메커니즘,

[키워드] acquisition Affect age association available data carried CD27 Comorbidities Course COVID-19 COVID-19 pandemic COVID19 cure Data mining death demonstrated distribution epidemiological epidemiological data Evidence evidence of Factor FIVE General population Genes genetic background genetic risk factor genetic risk factors Genetic variant Host Host genetic factor Infection inhibitor Innate immunity involved list list of gene MBL2 Mutation outcome polymorphism population distribution Population screening Prevalence protease Protein provide response SARS-CoV-2 SARS-COV-2 infection Serine serine 2 SNPs supported term text mining TMPRSS2 transmembrane variant
[DOI] 10.1016/j.ejmg.2021.104227 PMC 바로가기 [Article Type] Review