Acute Respiratory Distress Syndrome and Time to Weaning Off the Invasive Mechanical Ventilator among Patients with COVID-19 PneumoniaArticle Published on 2021-06-302022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] African American age ARDS CAP coronavirus disease COVID-19 Critical Critically ill Critically ill patient critically ill patients death distress ENhance examined Factor FIVE hospitalized patient IMV Invasive mechanical ventilation male management Mechanical Mortality Off outcome overall mortality Patient patients with COVID-19 Pneumonia respiratory Retrospective study SARS-CoV-2 severe ARDS severity syndrome the median time weaning white with COVID-19 [DOI] 10.3390/jcm10132935 PMC 바로가기 [Article Type] Article
Course of illness and outcomes in older COVID-19 patients treated with HFNC: a retrospective analysisResearch Paper Published on 2021-06-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, [키워드] acute respiratory distress acute respiratory distress syndrome Admission analyzed ARDS cause Course COVID-19 COVID-19 patient death Elderly patient elderly patients HFNC high mortality high-flow nasal cannula therapy Hospital stay Hospitalization hospitals ICU illness onset likelihood nasal no significant difference Older Organ failure outcome oxygen PaO Patient patients died receiving Retrospective analysis severe ARDS severely ill patients SOFA Spread suggested syndrome therapy treated viral shedding with COVID-19 [DOI] 10.18632/aging.203224 PMC 바로가기 [Article Type] Research Paper
Clinical Significance of Micronutrient Supplementation in Critically Ill COVID-19 Patients with Severe ARDSArticle Published on 2021-06-202022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory distress syndrome addition Admission anti-oxidative ARDS association Biomarker Biomarkers CD8 clinical Clinical data correlated COVID-19 Critical care Critically ill patient CRP data management Defense discharge elevated eligibility Essential ICU IgG IL-10 IL-1β IL-6 Ill immune response immunological Inflammation Inflammatory cytokines inflammatory parameters intensive care intravenous investigated Lymphocyte subset majority Micronutrient NK cell non-survivor nutrient supplementation organ damage oxidative stress PaO parameters Patient PCT peroxidase resulting Retrospective study screened selen SELENOP Selenoprotein P severe ARDS severe COVID-19 severe disease Significance significantly single-center suffered Support survived survivor syndrome T cell the patient Treatment with COVID-19 Zinc [DOI] 10.3390/nu13062113 PMC 바로가기 [Article Type] Article
Variation in outcome of invasive mechanical ventilation between different countries for patients with severe COVID-19: A systematic review and meta-analysisResearch Article Published on 2021-06-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval age Analysis ARDS Chinese Cochrane Library conducted country COVID 19 COVID 19 patient COVID-19 patients death discharge distress Egger’s test end point Endpoint estimate examined excluded finding FIVE Gas exchange had no heterogeneity high mortality homogeneity ICU IMV in-hospital mortality inclusion criteria indicated Infection Invasive mechanical ventilation Italy mechanical ventilation Meta-analysis Mortality mortality risk non-invasive ventilation outcome pandemic Patient patients with COVID-19 physician Publication bia reached Registered reported retrieved risk searched selected severe ARDS standard error statistically significant suggested Support syndrome systematic review tested treated Trial USA Validity was performed [DOI] 10.1371/journal.pone.0252760 PMC 바로가기 [Article Type] Research Article
Point of care diagnostic of hypercoagulability and platelet function in COVID-19 induced acute respiratory distress syndrome: a retrospective observational studyResearch Published on 2021-06-022022-10-29 Journal: Thrombosis Journal [Category] COVID-19, [키워드] abnormality acute respiratory distress acute respiratory distress syndrome Admission age Algorithm analysed analyzed ARDS bleeding Care Coagulation Coagulopathy Complication complications Coronavirus disease 2019 COVID-19 COVID-19 patients Critically ill diagnostic dysfunction elevated higher risk hypercoagulability Hypothesis ICU Impedance aggregometry indicated intensive care longitudinal major bleeding moderate no correlation occurred PaO parameter Patient patients with COVID-19 Platelet POCT Point point of care testing point-of-care respiratory Result retrospective risk severe ARDS single-center the patient therapeutic Thromboelastometry thromboembolic thromboembolic complication Thromboembolic event thrombosis [DOI] 10.1186/s12959-021-00293-8 PMC 바로가기 [Article Type] Research
Dexamethasone vs methylprednisolone high dose for Covid-19 pneumonia코비드-19 폐렴에 대한 덱사메타손 대 메틸프레드니솔론 고용량Randomized Controlled Trial Published on 2021-05-252022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, SARS, 임상, [키워드] acute respiratory syndrome Administered alveolar pressure Ambispective cohort study Analysis applied ARDS Berlin protocol C-reactive protein calculated can be used carried Chain Reaction Chest Chest tomography clinic Clinical outcome completion coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Corticosteroid COVID-19 pneumonia CRP D-dimer decrease Dexamethasone dexamethasone 6 mg DHL diagnosed discharge dose DXM effective therapy evaluated Follow-up followed by ground-glass imaging High dose high-complexity clinic high-dose methylprednisolone Hospitalization Hospitalized hospitalized patient hospitalized patients inclusion criteria Infectious disease Infectious diseases inspired oxygen fraction institutional protocol intensive care intensive care unit intravenous Invasive mechanical ventilation Laboratory laboratory result Laboratory results LDH less living-dead status marker material Medellín, Colombia Methylprednisolone Mortality MTP group Not applied optimal dose outpatient consultation oxygen P-value PaFi Patient patients treated Pneumonia polymerase chain polymerase chain reaction Prednisone proportion prospective cohort protocol Pulmonology radiological Randomized controlled studies readmission Recovery time required responsible Result Sample Sample size SARS-CoV2 Seven Severe acute respiratory syndrome severe ARDS Severe COVID-19 pneumonia severe SARS severity shown significantly statistically subsequent supplementary oxygen survival survival analysis telephone the patient tomography total population transfer treated Treatment [DOI] 10.1371/journal.pone.0252057 PMC 바로가기 [Article Type] Randomized Controlled Trial
Characteristics of Critically Ill Patients with COVID-19 Compared to Patients with Influenza—A Single Center ExperienceArticle Published on 2021-05-112022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress Admission ARDS Care center Comorbidities comparison Course COVID-19 COVID-19 patient creating disease ECMO experience extracorporeal membrane oxygenation First wave group health care systems help ICU Ill in both groups Influenza influenza infection intensive care less male Mortality not significantly different outcome pandemic Patient patients treated patients with influenza SARS-CoV-2 SARS-COV-2 infection Seasonal influenza severe ARDS severe disease similarity Spread standardized protocol syndrome time treated Treatment was used while with COVID-19 [DOI] 10.3390/jcm10102056 PMC 바로가기 [Article Type] Article
A two-arm, randomized, controlled, multi-centric, open-label phase-2 study to evaluate the efficacy and safety of Itolizumab in moderate to severe ARDS patients due to COVID-19COVID-19로 인한 중등도에서 중증 ARDS 환자에서 이톨리주맙의 효능과 안전성을 평가하기 위한 2군, 무작위, 대조, 다중 중심, 공개 라벨 2상 연구Clinical Trial Published on 2021-05-012022-09-12 Journal: Expert opinion on biological therapy [Category] MERS, SARS, 임상, 진단, [키워드] 95% CI acute respiratory distress acute respiratory distress syndrome anti-CD6 ARDS Complete coronavirus COVID-19 COVID-19 patient COVID-19 patients cytokine release Cytokine release syndrome death effective Efficacy and safety Enrollment evaluate evaluated events FiO2 FIVE IL-6 immune immune hyperactivation immunomodulatory immunomodulatory therapy Immunotherapy itolizumab lymphopenia mAb moderate necrotic objective Open-label outcome PaO2 Patient patients Randomized reaction receiving reduction in reduction in mortality replaced reported Result Safe screened severe ARDS SpO2 supportive care survival syndrome Transient treated Treatment Two patient Two-arm [DOI] 10.1080/14712598.2021.1905794 PMC 바로가기 [Article Type] Clinical Trial
The Use of Venovenous Extracorporeal Membrane Oxygenation in COVID-19 Infection: One Region’s Comprehensive ExperienceObservational Study Published on 2021-05-012022-10-04 Journal: ASAIO journal (American Society for Artificial Int [Category] SARS, 임상, [키워드] 95% CI acute respiratory distress ARDS Care center cohort study Comprehensive coronavirus disease COVID-19 COVID-19 case COVID-19 hospitalization COVID-19 infection demonstrated described discharge ECMO evaluated expected experience Extracorporeal extracorporeal membrane oxygenation Frequency highest hospital ICU ICU admissions ICU patient Infection Intensive intensive care Intervention intubation LOS management outcome Patient patients with ARDS Pneumonia positive recent Region resource secondary selected severe ARDS study period Support supported survival survived syndrome the patient V-V ECMO with COVID-19 [DOI] 10.1097/MAT.0000000000001403 PMC 바로가기 [Article Type] Observational Study
Predictors of Mortality in Critically Ill COVID-19 Patients Demanding High Oxygen Flow: A Thin Line between Inflammation, Cytokine Storm, and CoagulopathyResearch Article Published on 2021-04-202022-10-29 Journal: Oxidative Medicine and Cellular Longevity [Category] COVID-19, MERS, SARS, [키워드] accompanied Admission age albumin Analysis analyzed ARDS Belgrade Berlin center Chest CT Confirmed COVID-19 infection consecutive patient COVID-19 COVID-19 patient COVID-19 patients Critically ill Critically ill patient CRP D-dimer demographic Final hospital Hospital stay ICU identify IL-6 Ill independent predictor intensive care unit introduced invasive Invasive mechanical ventilation Laboratory LINE Logistic regression analysis lymphocyte median men moderate Mortality mortality rate multivariate logistic regression noninvasive Noninvasive ventilation Oxygen therapy past medical history Patient performed predictor respiratory Result selected serum albumin severe ARDS severity storm the median therapeutic Thin Treatment university were used [DOI] 10.1155/2021/6648199 PMC 바로가기 [Article Type] Research Article