Targeted SARS-CoV-2 treatment is associated with decreased mortality in immunocompromised patients with COVID-19Article Published on 2022-09-302022-11-15 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 변종, 진단, 치료제, [키워드] age anti-SARS-CoV-2 Antiviral case sery choice circulating variants COVID-19 curative curative treatment death death rate decreased mortality died Efficacy Follow-up Immunocompromised patient Immunocompromised patients IQR median monoclonal antibodies monoclonal antibody omicron outcome Patient Prophylaxis receive recorded Remdesivir reported retrospective Safe SARS-CoV-2 treatment severe adverse event severe COVID-19 significantly lower Tolerance treated patient treated patients Treatment treatment availability Treatment protocol with COVID-19 [DOI] 10.1093/jac/dkac253 PMC 바로가기
Hygienic behaviors during the COVID-19 pandemic may decrease immunoglobulin G levels: Implications for Kawasaki diseaseArticle Published on 2022-09-282022-11-15 Journal: PLoS ONE [Category] 진단, [키워드] accelerated Adults Affect all age group all age groups children control subject coronavirus disease COVID COVID-19 COVID-19 outbreak COVID-19 pandemic Decline declined decrease examined explain Health hygiene Hypothesis IgE IgG IgG level Immunoglobulin immunological parameter individual Infection Kawasaki disease Neonate nonspecific pandemic Patient predict quantified recorded significantly lower steadily decreased [DOI] 10.1371/journal.pone.0275295 PMC 바로가기
Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 VaccineArticle Published on 2022-09-282022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 진단, [키워드] acute respiratory syndrome allergic allergic reaction anaphylaxis antibody antigenic target Control controls coronavirus coronavirus 2 coronavirus disease COVID-19 exhibiting full-length functional humoral Humoral immunity hypersensitivity IgG1 Immunoglobulin individual messenger Messenger RNA Moderna mounted mRNA mRNA COVID-19 vaccine occur Patient Pfizer produced profile reaction receptor recipients reduction in respiratory RNA SARS-CoV-2 significantly lower Symptom systems serology vaccination Vaccine [DOI] 10.1093/infdis/jiac107 PMC 바로가기
A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamstersArticle Published on 2022-09-272022-11-15 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, 치료기술, 치료제, [키워드] acute respiratory syndrome Administered Antiviral effect coronavirus COVID-19 pandemic delta variant Detection limit disease dose effective Efficacy exhibited hamster hamsters highest Infectious virus Inflammatory cytokines Intervention intranasally intrinsically limit Lipid nanoparticle Lower mucosa nasal Particle Pathogenesis Postinfection Prevent reduce reduced reported respiratory tissue respiratory virus SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2 transmission SARS-CoV-2 viral shedding severe disease severe lung pathology significantly lower suppress tested therapeutic therapeutic interfering particles TIP tissue Transmissibility Transmission uninfected variants viral loads viral replication while [DOI] 10.1073/pnas.2204624119 PMC 바로가기
Wellbeing and coping of UK nurses, midwives and allied health professionals during COVID-19-a cross-sectional studyArticle Published on 2022-09-212022-11-16 Journal: PLoS ONE [Category] SARS, 변종, [키워드] backbone benefit Burnout Care conducted COPE coping coping strategies Coping strategy COVID-19 pandemic cross-sectional cross-sectional survey Descriptive statistics Deterioration Effect examined family Final Health healthcare Healthcare professional healthcare services inventory life mental health Multiple linear regression Nurse Nurses patients with COVID-19 phase Phase 1 Phase 2 Prevent professional Psychological Quality repeated respond scale significant effect significantly lower Strategy Stressor timepoints United Kingdom variable variant work [DOI] 10.1371/journal.pone.0274036 PMC 바로가기
Impact of COVID-19 on viral respiratory infection epidemiology in young children: A single-center analysisArticle Published on 2022-09-202022-11-15 Journal: Frontiers in Public Health [Category] SARS, 치료기술, [키워드] Analysis analyzed benefit Bonferroni correction children Concomitant COVID-19 COVID-19 pandemic described epidemiological Epidemiology Fisher Health Hypothesis IAV IBV Impact indicated Infectious disease Influenza influenza A Influenza virus Intervention no significant difference Non-pharmaceutical interventions not significantly different NPI NPIs observé occurred Occurrence outpatient clinic pandemic parainfluenza virus 3 pediatric presented later presenting reduce reduction in reported respiratory respiratory infection respiratory pathogen respiratory syncytial virus RSV SARS-CoV-2 SARS-CoV-2 PCR tests significantly significantly higher significantly lower single-center Spread study period Surveillance tested University Hospitals Leuven viral respiratory infection virus were used [DOI] 10.3389/fpubh.2022.931242 PMC 바로가기
SARS-CoV-2 Seroprevalence Study in Pediatric Patients and Health Care Workers Using Multiplex Antibody ImmunoassaysArticle Published on 2022-09-142022-11-15 Journal: Viruses [Category] SARS, 변종, 진단, 치료기술, [키워드] Adults affected antibody Antigen Beta children circulating Clinical characteristics Cohort correlation COVID-19 delta variant disease ELISA estimate exacerbated False positive Gamma group HCW Health healthcare healthcare worker Healthcare workers highlight hospitals IgA IgA response IgG IgM indicated Infection isotype lowest Luminex assay Mild nucleocapsid PIMS-TS positive correlation RBD recruited SARS-CoV-2 SARS-CoV-2 proteins sensitivity Seropositivity Seroprevalence significantly lower Spain Spanish specificity study period the receptor-binding domain variants were measured worker [DOI] 10.3390/v14092039 PMC 바로가기
The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individualsArticle Published on 2022-09-132022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 치료제, [키워드] analyzed anti-SARS-CoV-2 anticancer Bone marrow Cancer cancer cell cancer cell lines cancer patient Cancer patients chemokine combating cordycepin cordycepin (CD). correlated COVID-19 COVID-19 pandemic domain exhibited expression functional healthy healthy individual highest immune Immune cell infiltration immune infiltration individuals information inhibit Invasion ISG20 ISG20 expression isoform less Lymphocytes lymphoid tissues marker Methylation MHC molecule mRNA expression mutant N6 N6-dimethyladenosine (m 6 2A) outcome overexpression promoter receptors Regulation SARS-CoV-2 SARS-COV-2 infection significantly significantly increased significantly lower small molecule survival survival rate susceptibility the median therapeutic potential tissue tissues traditional Chinese medicines treat tumorigenesis underlie virus were used [DOI] 10.3389/fimmu.2022.958898 PMC 바로가기
Effect of Coronavirus Disease (COVID-19) on Human Semen: No Evidence of Coronavirus in Semen of PatientsArticle Published on 2022-09-122022-11-15 Journal: BioMed Research International [Category] SARS, 치료기술, [키워드] acute respiratory syndrome addition Analysis analyzed Blood both group China clinical recovery Concentration coronavirus COVID-19 disease Effect evaluate evidence of fertile Human men morphology no significant difference organs Oropharyngeal parameter Patient PCR test secreted Semen shown significantly lower specimen tested two groups Urine viability virus was done with COVID-19 [DOI] 10.1155/2022/6204880 PMC 바로가기
Kinetics of anti-SARS-CoV-2 antibody titer in healthy adults up to 6 months after BNT162b2 vaccination measured by two immunoassays: A prospective cohort study in JapanArticle Published on 2022-09-092022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] Abbott acute respiratory syndrome Adults age anti-RBD Anti-RBD antibody anti-RBD antibody response anti-receptor-binding domain anti-SARS-CoV-2 antibody Anti-SARS-CoV-2 S antibody Antibody Response Antibody titer Architect Architect SARS-CoV-2 IgG II Quant assays blood sample BNT162b2 BNT162b2 mRNA vaccine BNT162b2 vaccine collected comparable Coronavirus-2 correlation dose Elecsy Elecsys Elecsys Anti-SARS-CoV-2 S evaluated first vaccination geometric GMT GMT ratio GMTs healthcare healthy immunoassay immunoassays Japan Kinetics mRNA vaccine no significant difference Older age Participants prospective cohort study RBD Roche Diagnostics SARS-CoV-2 SARS-CoV-2 IgG second vaccination Sex significantly lower Spearman vaccination were measured [DOI] 10.1016/j.vaccine.2022.08.018 PMC 바로가기