Reliable and Scalable SARS-CoV-2 qPCR Testing at a High Sample Throughput: Lessons Learned from the Belgian InitiativeArticle Published on 2022-01-212022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] approach assays automated Belgium build components COVID-19 Data analysis disparate equipment force Government heterogeneous high-throughput testing Infection information initiative introduced lab automation lesson management manual intervention methodology molecular National pandemic platform Protective protocols qc monitoring qPCR Quality control reagents resources responsible robust Sample SARS-CoV-2 Standardization Testing the patient [DOI] 10.3390/life12020159 PMC 바로가기 [Article Type] Article
Evaluation of Commercial Anti-SARS-CoV-2 Antibody Assays and Comparison of Standardized Titers in Vaccinated Health Care Workers상업용 Anti-SARS-CoV-2 항체 분석 평가 및 예방 접종을 받은 의료 종사자의 표준화된 역가 비교Article Published on 2022-01-192022-09-11 Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, 치료기술, [키워드] Abbott acute respiratory syndrome anti-RBD antibody Antibody titers antigens assays BAU binding bioMérieux calibration Care commercial assays convalescent individuals conversion factor Coronavirus-2 correlated detect DiaSorin dose evaluated Express FIVE HCW Health Health care Health care worker health care workers Health Organization immunization immunoassay include individuals Infection international standard naïve individuals Pearson correlation coefficient provided quantification Quantitative quantitative assay Quantitative assays RBD RBD IgG Receptor binding domain respiratory SARS-CoV-2 SARS-CoV-2 antibodies sera Seroconversion Siemen Siemens Siemens Healthineer significant difference significant differences spike glycoprotein spike IgG Standard Standardization standardized titers titer vaccination Vaccine Vaccines was used were measured worker World Health Organization [DOI] 10.1128/JCM.01746-21 PMC 바로가기 [Article Type] Article
Monitoring SARS-CoV-2 in sewage: Toward sentinels with analytical accuracy하수 내 SARS-CoV-2 모니터링: 분석 정확도로 센티넬을 향하여Article Published on 2022-01-152022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 biases Cellulose Combination comparable Concentration coronavirus Delft diethylaminoethyl cellulose Effect Epidemiology evaluated False negative false negatives filtered filtration Health help implementation introduced Isolation Magnetic beads membrane membranes Method harmonisation Mitigation molecular monitoring Netherlands not adapted Outbreaks Pandemia pandemic Patient protocol protocols Result RNA isolation RNA purification RT-qPCR sampling SARS-CoV-2 SARS-CoV-2 virus SARS-CoV-2 viruses severe acute respiratory syndrome Coronavirus sewage Standardization Surveillance urgency Variability Viral load Viral particles Viral RNA Volume wastewater Wastewater-based epidemiology water were used [DOI] 10.1016/j.scitotenv.2021.150244 PMC 바로가기 [Article Type] Article
Simplified Point-of-Care Full SARS-CoV-2 Genome Sequencing Using Nanopore TechnologyProtocol Published on 2021-12-162022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] (+)RNA genome sequencing Amplicon applied bioinformatics Combination conducted Coverage COVID-19 surveillance criteria Ct value decrease described experiment genome coverage help less local outbreak overlapping Oxford parameter PCR primer set protocol qPCR Rapid recognize SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 pandemic SARS-CoV-2 variant SARS-CoV-2-positive specimen Sequencing specimen specimens Standardization Surveillance technology tested threshold time-consuming variant-of-concern (VOC) variant-of-interest (VOI) variants of concern [DOI] 10.3390/microorganisms9122598 PMC 바로가기 [Article Type] Protocol
COVID-19 Vaccine Perceptions, Intentions, and Uptake Among Young Adults in the United States: Prospective College-Based Cohort StudyOriginal Paper Published on 2021-12-152022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, SARS, [키워드] Adults approval asked black calculate Cohort college COVID-19 COVID-19 transmission COVID-19 vaccination COVID-19 vaccine demographic groups Hesitancy higher education Immunity Intention less Minority objective Older participant Participants Perception Population prevalence ratio Prospective race Racial receive Result serology significantly more Standardization the vaccine understanding uptake vaccination Vaccination Status Vaccine was used white young adult [DOI] 10.2196/33739 PMC 바로가기 [Article Type] Original Paper
The effectiveness of commercial household ultraviolet C germicidal devices in ThailandArticle Published on 2021-12-132022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] acute respiratory syndrome coronavirus coronavirus disease determine dosage effective Effectiveness Environmental sciences equipment evaluate Health care hygiene IMPROVE inactivation Infectious diseases introduced lack pandemic required SARS-CoV-2 Seven Side effect Standard Standardization ultraviolet ultraviolet C was measured [DOI] 10.1038/s41598-021-03326-4 PMC 바로가기 [Article Type] Article
Genophenotypic Factors and Pharmacogenomics in Adverse Drug ReactionsReview Published on 2021-12-102022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] administration ADR ADRS Adverse Adverse drug reaction Adverse drug reactions age benefit Biomarker Brain Cancer cardiovascular disease Cardiovascular disorders cause central nervous system disorders clinical setting COVID-19 cutaneous ADRs death disorders drug Drug efficacy Drug–drug interactions effective Factor feature genomic Genotype Health implementation involved lack limitation Major Microarray NGS organizations pathology pharmacogenomics physician problem Prospective Study provide reaction Regulation Sex Standardization Toxicity Vaccination strategies with COVID-19 [DOI] 10.3390/ijms222413302 PMC 바로가기 [Article Type] Review
Guidelines on the treatment with integrated traditional Chinese medicine and western medicine for severe coronavirus disease 2019심한 코로나 바이러스 질병 2019를위한 통합 된 중국 의약 및 서양 의학 치료에 관한 지침Practice Guideline Published on 2021-12-012022-08-31 Journal: Pharmacological research [Category] MERS, SARS, 치료제, [키워드] assessment Care characterized Chinese complex complications coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients develop development Diagnosis disease Guidance guideline Health personnel healthcare healthcare professionals high mortality integrated Chinese and Western medicine involved item Practice public health public health personnel rehabilitation Reporting researcher severe coronavirus disease severe COVID-19 Standardization TCM the epidemic Traditional Chinese medicine Treatment treatment of COVID-19 [DOI] 10.1016/j.phrs.2021.105955 PMC 바로가기 [Article Type] Practice Guideline
Nanodispersions of Polyelectrolytes Based on Humic Substances: Isolation, Physico-Chemical Characterization and Evaluation of Biological ActivityArticle Published on 2021-11-182022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] activity antiviral activity approach binding Bioactivity Biological Cell Characteristics characterization complex complexes concentrations contribute coronavirus demonstrated detect Dilution dried droplet method effective EHA element fluorescent Frame heterogeneity humic and fulvic acids include increase in increasingly initial introduced Isolation lack medium molecular nanodispersion natural optical organ Particle particle size measurement Particles physico-chemical property polydispersity antiviral activity Polyelectrolyte polyelectrolytes Prevent Quality control Radiation receptor regulated Regulatory SEM shown spike glycoprotein stability Standardization submicron Taking the SARS-CoV-2 virus Vero E6 VERO-E6 virucidal virus X-ray zeta potential [DOI] 10.3390/pharmaceutics13111954 PMC 바로가기 [Article Type] Article
A Highly Sensitive and Specific SARS-CoV-2 Spike- and Nucleoprotein-Based Fluorescent Multiplex Immunoassay (FMIA) to Measure IgG, IgA, and IgM Class AntibodiesResearch Article Published on 2021-11-172022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome analyses antibody antibody concentration assays Biosafety Level 3 BSL-3 calibrated calibration class collected comparability Concentration Concordance coronavirus coronavirus disease correlated strongly correlation COVID-19 enzyme fluorescent gold standard identify IgA IgG IgM Immunity immunoassay IMPROVE Infection International measure microneutralization Microneutralization test MNT moderate multiplex NAb titer NAb titers NAbs neutralization test Neutralizing antibodies neutralizing antibody neutralizing antibody titers nucleoprotein pandemic persistence population immunity quantification Receptor-binding domain SARS-CoV-2 SARS-CoV-2 antibody sensitive sensitivity Serological assay serological assays Specific specificity spike spike glycoprotein Standard Standardization Surveillance Symptom the WHO vaccination validation WHO WHO International Standard World Health Organization [DOI] 10.1128/Spectrum.01131-21 PMC 바로가기 [Article Type] Research Article