Integrated COVID-19 Predictor: Differential expression analysis to reveal potential biomarkers and prediction of coronavirus using RNA-Seq profile data통합 COVID-19 예측자: RNA-Seq 프로필 데이터를 사용하여 잠재적인 바이오마커 및 코로나바이러스 예측을 밝히기 위한 차등 발현 분석Article Published on 2022-08-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, [키워드] Accuracy adjusted Analysis applied association bioinformatics Biomarker classification Classifier collected Consensus Control coronavirus COVID-19 COVID-19 cases COVID-19 pandemic DEGs DESeq2 Differential expression analysis differentially expressed gene Differentially expressed genes disease transmission down-regulated genes experiment experimental analysis expressed feature filtered gene count Genome healthy identify input intersection and union issue Limma machine machine learning machine learning model machine learning models matter moderate P-value pandemic performed Potential biomarker potential biomarkers predict prediction predictor processed RNA-Seq SARS-CoV-2 SARS-CoV-2 virus sequence significantly Spread statistical SVM the SARS-CoV-2 virus trend up-regulated viral disease Virology [DOI] 10.1016/j.compbiomed.2022.105684 PMC 바로가기 [Article Type] Article
The comparative effectiveness of COVID-19 monoclonal antibodies: A learning health system randomized clinical trialRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: Contemporary clinical trials [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 95% CI adjusted odds ratio age Analysis antibody authorization Bayesian COVID-19 criteria death decrease defined Effectiveness Emergency enrolled equivalence funding Government Health health system Hospitalization inferiority IQR Local mAb median Mild moderate Moderate COVID-19 monoclonal neutralize Odds ratio outcome Patient Placebo Platform trial posterior probability Probability provided random randomized clinical trial Registered relative reported SARS-CoV-2 Sex statistical Treatment Trial [DOI] 10.1016/j.cct.2022.106822 PMC 바로가기 [Article Type] Randomized Controlled Trial
Efficacy and effectiveness of SARS-CoV-2 vaccines for death prevention: A protocol for a systematic review and meta-analysis사망 예방을 위한 SARS-CoV-2 백신의 효능 및 효과: 체계적인 검토 및 메타 분석을 위한 프로토콜Article Published on 2022-07-282022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, meta-analysis, SARS, [키워드] adverse event all-cause mortality analyzed approved assessment Bia calculated case-control studies case-control study Cohort controlled trials COVID-19 death deaths effective Effectiveness Efficacy Egger eligible Evidence exploratory for inclusion forest plot forest plots funnel plot hazard hazard ratios heterogeneity Hospitalization incident independent intervals Intervention Meta-analysis Mortality Observational data outcome Placebo Prevent Primary outcome PROSPERO protocol Publication bia publication bias randomized control trial Randomized controlled trials RCT Record reducing Registered risk reduction SARS-CoV-2 vaccine SARS-CoV-2 vaccines Secondary outcomes Severe case severe cases statistical statistical test systematic review the vaccine the vaccines university vaccination Vaccination Status Vaccine visual inspection York [DOI] 10.1371/journal.pone.0265414 PMC 바로가기 [Article Type] Article
Impact of a phone call with a medical student/general practitioner team on morbidity of chronic patients during the first French COVID-19 lockdown (COVIQuest): a cluster randomised trialRandomized Controlled Trial Published on 2022-07-282022-10-04 Journal: BMJ Open [Category] 임상, [키워드] 95% CI Admission approach chronic cardiovascular Chronic diseases Cluster Contact control group COVID-19 CVD disease disorder eight evaluate French healthcare hospitalisation hospitalised Impact intervention group lack lockdown mental health morbidity older patient outcome Patient Preventive medicine primary care randomised controlled trial Randomised trial reduce reduced regions risk significantly statistical the patient usual care [DOI] 10.1136/bmjopen-2021-059464 PMC 바로가기 [Article Type] Randomized Controlled Trial
Large-scale application of free energy perturbation calculations for antibody design항체 설계를 위한 자유 에너지 섭동 계산의 대규모 적용Article Published on 2022-07-212022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] antibody applicability automated binding affinity calculate case study Combination conformational evaluate facilitate fraction free energy implementation m396 majority melting temperatures Mutation parameters predict predicted problem protocol reduced sampling SARS-CoV-1 SARS-CoV-2 Spike proteins stability statistical the binding affinity the spike protein variant variants [DOI] 10.1038/s41598-022-14443-z PMC 바로가기 [Article Type] Article
Urban monitoring, evaluation and application of COVID-19 listed vaccine effectiveness: a health code blockchain studyCOVID-19 등재 백신 효과의 도시 모니터링, 평가 및 적용: 건강 코드 블록체인 연구Article Published on 2022-07-132022-09-11 Journal: BMJ Open [Category] 변종, [키워드] aggravate Algorithm analysed Analysis Asymptomatic average basic reproduction number calculate city Complete conditions Contact cooperation country COVID-19 decrease deviation Effectiveness eight ENhance epidemiological Epidemiological investigation Epidemiology evaluate greater Health Health policy herd immunity Immunity increase Incubation period index infection rate information measure MONITOR mutant virus not decreased outcome Patient Primary outcome Primary outcomes promote promoted proportion protective effect reduced regions respond second significantly Simulation statistical symptomatic the vaccine this system transmitted urban urban population vaccination vaccination rate Vaccination strategy Vaccine Vaccines variant Variation virus weight [DOI] 10.1136/bmjopen-2021-057281 PMC 바로가기 [Article Type] Article
Impact of cancer types on COVID-19 infection and mortality risk: a protocol for systematic review and meta-analysisCOVID-19 감염 및 사망 위험에 대한 암 유형의 영향 : 체계적인 검토 및 메타 분석을위한 프로토콜Article Published on 2022-07-082022-08-31 Journal: BMJ Open [Category] MERS, meta-analysis, [키워드] addition affected approval Cancer cancer type Care changed China collaboration complications COVID-19 COVID-19 infection COVID-19 pandemic database death Diagnosis eligible Epidemiology Ethics evaluated Formal higher risk Impact independent individual Infrastructure journal management measure Meta-analysis Mortality mortality risk Newcastle-Ottawa Scale oncology Patients with cancer peer-reviewed performed preventive measures PROSPERO protocol registration number required review risk risk of bia Science Seven shown significantly SinoMed statistical systematic review technology the Newcastle-Ottawa Scale Treatment [DOI] 10.1136/bmjopen-2021-058078 PMC 바로가기 [Article Type] Article
A Review of the Presence of SARS-CoV-2 in Wastewater: Transmission Risks in Mexico폐수 내 SARS-CoV-2 존재에 대한 검토: 멕시코의 전파 위험Review Published on 2022-07-082022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected Analysis appearance caution center Commission Community Contagion coronavirus correlation Coverage COVID-19 debate determine Early detection Epidemiology epidemiology of wastewater Evidence evidence of Health health authorities help highlight identify indicate information International Johns Hopkin Johns Hopkins measure mechanism Municipal wastewater occur percentage percentages plant positive Presence Probability Research review Ribonucleic acid risk risks of transmission SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 RNA Secretary sewage Spread statistical Surveillance Transmission treated Treatment virus virus transmission was obtained was performed wastewater water zone [DOI] 10.3390/ijerph19148354 PMC 바로가기 [Article Type] Review
A synergistic mindsets intervention protects adolescents from stress Research Published on 2022-07-062022-10-05 Journal: Nature [Category] 치료법, [키워드] Analysis anxiety symptom Bayesian benefit conducted confidence COVID-19 double-blind experiment growth heterogeneous Intervention lockdown machine-learning Mental physiological PROTECT Psychological well-being Randomized reactivity Research response resulting scaled statistical Stress synergistic target The United States Treatment [DOI] 10.1038/s41586-022-04907-7 [Article Type] Research
Effect of environmental factors on SARS-CoV-2 infectivity in northern hemisphere countries: a 2-year data analysis북반구 국가의 SARS-CoV-2 감염력에 대한 환경 요인의 영향: 2년 데이터 분석Article Published on 2022-07-012022-09-11 Journal: Public health [Category] COVID19(2023년), SARS, 변종, [키워드] addition analyses Analysis approach average caused correlation Correlation analysis country COVID-19 COVID-19 case COVID-19 cases COVID-19 incidence COVID-19 pandemic Data analysis death Effect Environment Environment temperature environmental factor environmental factors epidemiological studies Epidemiological study evidenced extension global analysis Humidity indicated mutant strain Mutant strains negative correlation Northern hemisphere pandemic Pearson pilot study reported Research risk factor SARS-CoV-2 Spearman standstill statistical Sunlight temperature Univariate analysis variant Winter Wuhan [DOI] 10.1016/j.puhe.2022.04.011 PMC 바로가기 [Article Type] Article