A Randomized Open label Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease (RECOVER): A structured summary of a study protocol for a randomised controlled trial
Letter
[키워드] 1:1
active cancer
addition
administration
age
ambient
analysed
anti-SARS-CoV-2
Antibody titer
antibody titres
anticipated
ARMS
assessment
baseline
Blinding
Block randomisation
breathing ambient air
case report form
changes in
Chemotherapy
clearance
clinical
clinical condition
Clinical outcome
collected
Confirmed
Contact
convalescence
convalescent plasma
COVID-19
criteria
cross
cytokine profile
D-dimer
death
defined
described
diagnostic
discharge
discharged patient
dissemination
Donor
Duration
early application
eCRF
Effect
element
eligibility
eligible
eligible patient
Enrollment
EudraCT
exclusion criteria
expected
experimental arm
exploratory
feature
Follow-up
follow-up period
group
Hematological malignancy
high risk
high-risk patient
high-risk patients with severe disease
hospital
Hospital admission
Hospital stay
Hospitalized
Immunosuppression
inclusion criteria
Infection
infusion
investigator
laboratory data
Last
less
mechanical ventilation
multicenter
non-parametric test
number
objective
Open-label
outcome
overall survival
participant
Patient
performed
plasma
positive
protocol
quarter
Radiotherapy
randomisation
randomised
randomised controlled trial
randomization system
Randomized
receive
recruitment
Registered
report
reported
required
Requirement
risk
routine care
Sample size
SARS-CoV-2
SARS-CoV-2 antibody
SARS-CoV-2 disease
SARS-COV-2 infection
SARS-CoV-2 viral
schedule
secondary
Secondary objective
Seven
seven-point ordinal scale
Standard
Standard of care
status
Stratification
Study protocol
subject
survival
survival rate
survival rates
Swab
table
the patient
therapy
time
Total
treated
Treatment
Trial
underlying disease
Viral load
website
worsening
[DOI] 10.1186/s13063-020-04735-y PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04735-y PMC 바로가기 [Article Type] Letter