KG-Predict: A knowledge graph computational framework for drug repurposingResearch article Published on 2022-08-012022-10-05 Journal: Journal of biomedical informatics [Category] 신약개발, [키워드] Alzheimer’s disease applied association AUROC biochemical candidate drug characteristic clinical trial complex composed Computational prediction framework database drug Drug discovery Drug repurposing drugs experiments Genetic genotypic heterogeneous information interactions knowledge Knowledge graph limitation offered phenotypic the mean therapeutic [DOI] 10.1016/j.jbi.2022.104133 [Article Type] Research article
The impact of COVID-19 pandemic on individuals at clinical high-risk for psychosis: Evidence from eye-tracking measuresResearch article Published on 2022-08-012022-10-05 Journal: Progress in neuro-psychopharmacology & biological [Category] 바이오마커, 임상, [키워드] abnormality Accuracy amplitude Biomarker caused Characteristics checklist Clinical high-risk for psychosis Clinical symptoms COVID-19 COVID-19 pandemic distress DSM-5 Effect Evidence eye Eye movement fixation healthy healthy control high risk Impact individual individuals information investigated measure Mental disorder negatively affected Pandemics participant Participants Perceived Stress Scale physiological post-traumatic provide PSS-10 Psychological distress PTSD reported saccade scale severity significantly significantly higher stability stratified Stress subgroups suggested Symptom the mean total score were assessed were measured [DOI] 10.1016/j.pnpbp.2022.110578 [Article Type] Research article
Effects of aquatic physical exercise on motor risk factors for falls in older people during the COVID-19 pandemic: a randomized controlled trialResearch article Published on 2022-08-012022-10-05 Journal: Journal of Manipulative and Physiological Therapeutics [Category] 임상, [키워드] Aged amplitude carried cognitive Control COVID-19 COVID-19 diagnosis COVID-19 pandemic Effect eye Falls group Health Hydrotherapy Intervention MONITOR muscle Muscle strength muscular Older pandemic participant performed physical Physical exercise platform positive Randomized controlled trial reduced risk factor significant decrease significantly stability the mean training [DOI] 10.1016/j.jmpt.2022.08.002 [Article Type] Research article
Prevention and treatment of COVID-19 infection by earthingResearch article Published on 2022-08-012022-10-05 Journal: Biomedical journal [Category] SARS, 변종, 치료법, 치료제, [키워드] All participant anorexia anti-inflammatory effect anticoagulation applied Blood blood oxygen level carried chest pain conducted Contact coronavirus cough COVID-19 infection COVID-19 prevention COVID-19 treatment Critically ill died Dyspnea Earthing Effect Fever Grounding headache illness duration Immunity Infection Measures Mild oxygen oxygen supply Oxygenation Pain Patient prevention prevention of COVID-19 Previous studies Prophylactic raised Result rising risk factor SARS-CoV-2 short-lived Symptom the mean the median Treatment Two patient weakness with COVID-19 [DOI] 10.1016/j.bj.2022.08.002 [Article Type] Research article
The effect of SARS-CoV-2 vaccination on post-acute sequelae of COVID-19 (PASC): A prospective cohort studySARS-CoV-2 백신 접종이 COVID-19의 급성 후유증(PASC)에 미치는 영향: 전향적 코호트 연구Article Published on 2022-07-302022-09-12 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 1:1 age antibody association Bayesian comparable COVID-19 Critical enrolled Evidence Follow-up follow-up period full recovery groups Hierarchical illness onset immunological IMPROVE Linear regression Logistic regression Long Long COVID mechanism median Mild not differ number of symptom obesity participant Participants PASC Patient Post-acute sequelae proportion prospective cohort study RBD-binding IgG reported SARS-CoV-2 SARS-CoV-2 vaccination Sex spike Symptom the mean therapeutic effect therapeutic vaccine trajectory vaccination [DOI] 10.1016/j.vaccine.2022.05.090 PMC 바로가기 [Article Type] Article
COVID-19 Associated Guillain-Barré Syndrome: A Report of Nine New Cases and a Review of the LiteratureCOVID-19 관련 길랑-바레 증후군: 9건의 신규 사례 보고 및 문헌 검토Review Published on 2022-07-222022-09-12 Journal: Medicina [Category] MERS, 진단, [키워드] Admission analyzed case sery causes characterized clinical Clinical features conditions conducted Course COVID-19 COVID-19 patient COVID-19 symptom Department Diagnosis died discharge dysfunction Guillain–Barrè syndrome Hospitalized Immune-mediated immunoglobulins Inflammatory intravenous literature literature review manifested mechanical ventilation mortality rate neurological NEUROLOGY New notable outcome Patient peripheral neuropathies plasma polyneuropathies positive Registered report required Respiratory failure review Romania Symptom Symptoms syndrome the mean Treatment variable [DOI] 10.3390/medicina58080977 PMC 바로가기 [Article Type] Review
Noninvasive ventilation in COVID-19 patients aged ≥ 70 years-a prospective multicentre cohort studyObservational Study Published on 2022-07-222022-10-05 Journal: Critical Care [Category] 임상, [키워드] 30-Day mortality 95% CI Admission age assessment Care CFS clinical cohort study COVID-19 COVID-19 pandemic COVID-19 patient Critically ill death defined elderly Endotracheal intubation enrolled Europe European European country evaluate Factor failure frailty Frequency ICU ICU admission IMV intensive care intensive care unit International Invasive mechanical ventilation male multicentre NIV Noninvasive ventilation occurred Older outcome Patient patients patients treated primary endpoint prospective observational study Registered Registration risk scale severity SOFA the mean treated Ventilation with COVID-19 [DOI] 10.1186/s13054-022-04082-1 PMC 바로가기 [Article Type] Observational Study
Effect of Omega-3 fatty acid supplementation on sexual function of pregnant women: a double blind randomized controlled trial Research Published on 2022-07-192022-10-05 Journal: International Journal of Impotence Research [Category] 임상, [키워드] Anxiety approved baseline clinical control group control groups Controlled clinical trial Data collection double blind double-blind Effect Effectiveness Energy intake ethics committee evaluate the effect fatty female Follow-up gestation health center IMPROVE Intervention intervention group Medical Science omega-3 omega-3 fatty acid omega-3 supplement performed Placebo Polyunsaturated Pregnancy pregnant pregnant women prenatal care questionnaire Randomized Randomized controlled trial recall receive Registered registry significantly higher significantly lower statistically significant statistically significant difference the mean total score university Van [DOI] 10.1038/s41443-022-00598-w [Article Type] Research
Neurologic manifestations of COVID-19 in critically ill patients: results of the prospective multicenter registry PANDEMICObservational Study Published on 2022-07-162022-10-05 Journal: Critical Care [Category] COVID19(2023년), SARS, 임상, [키워드] 350 patients 95% CI age Analysis Care category cerebrospinal fluid Cohort Complication coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical Critically ill diagnose disorder enrolled Evidence Factor functional hemorrhage hospital discharge ICU ICU Patients identify increasingly Infection intensive care intensive care unit male manifestation Manifestations morbidity Mortality multicenter nervous system neurologic neurologic disorder neurologic manifestations neurological manifestation New outcome Patient patients patients with COVID-19 performed positive Postinfectious predictor Prevalence reported reverse transcriptase PCR risk factor searched statistical analyses stroke study period surviving patient the mean treated were used [DOI] 10.1186/s13054-022-04080-3 PMC 바로가기 [Article Type] Observational Study
Multisystem Inflammatory Syndrome Associated With COVID-19 in Children (MIS-C): A Systematic Review of Studies From India어린이의 COVID-19와 관련된 다기관 염증 증후군(MIS-C): 인도 연구의 체계적인 검토Article Published on 2022-07-152022-09-11 Journal: Indian pediatrics [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Admissions age article calculate children clinical Clinical features coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids Course COVID-19 database databases derangement disease course disease status Effect feature Features Fever Frequency Future gastrointestinal problem gastrointestinal problems GraphPad GraphPad software Health Organization Immunoglobulin India Inflammatory Inflammatory marker inflammatory markers intensive care Intravenous immunoglobulin IQR Kawasaki disease laboratory parameter Laboratory parameters majority male median MIS-C mortality rate NIH parameter Patient patients ranged reported required review SARS-COV-2 infection Screening Standard deviation syndrome systematic review the disease the mean Therapeutics Treatment was done was used World Health Organization [DOI] 10.1007/s13312-022-2559-5 PMC 바로가기 [Article Type] Article