Point-of-care molecular testing and antiviral treatment of influenza in residents of homeless shelters in Seattle, WA: study protocol for a stepped-wedge cluster-randomized controlled trial워싱턴주 시애틀의 노숙자 보호소 거주자를 대상으로 한 현장 진료 분자 검사 및 인플루엔자 항바이러스 치료: 계단식 쐐기형 클러스터 무작위 대조 시험을 위한 연구 프로토콜Study Protocol Published on 2020-11-232022-09-10 Journal: Trials [Category] SARS, 임상, 치료제, [키워드] acute respiratory illness Administered age Analysis Antiviral treatment ARI baloxavir Comorbidities Complete control arm Controlled trial defined demographics eligible Enrollment evaluate health problem homeless shelter Homeless shelters implementation incidence individual Influenza information Intervention intervention arm molecular nine oseltamivir participant point-of-care positive primary endpoint public health questionnaire Randomized reduce respiratory respiratory symptom Seattle severity Site Spread Study protocol supplementary material Surveillance symptom duration symptom onset Symptoms tested timepoint Trial Trial registration University of Washington Washington worsening cough [DOI] 10.1186/s13063-020-04871-5 PMC 바로가기 [Article Type] Study Protocol
Association of poor housing conditions with COVID-19 incidence and mortality across US countiesResearch Article Published on 2020-11-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adjusted adverse outcome association census center Characteristics Comorbidities condition conditions conducted Control COVID-19 COVID-19 incidence COVID-19 mortality COVID-19 test cross-sectional analysis death demographics effort greater Health healthcare higher risk incidence incidence rate increase in individual Infectious disease investigated linear modeling mitigate Mortality mortality rate ratio objective outcome Poor Prevalence remained Result risk Spread Support the mean timepoint total population with COVID-19 [DOI] 10.1371/journal.pone.0241327 PMC 바로가기 [Article Type] Research Article
Longitudinal correlation of biomarkers of cardiac injury, inflammation, and coagulation to outcome in hospitalized COVID-19 patientsResearch article Published on 2020-10-012022-10-05 Journal: Journal of molecular and cellular cardiology [Category] SARS, 바이오마커, [키워드] Admission age Biomarker biomarkers of inflammation C-reactive protein cardiac injury Coagulation coronavirus disease correlated correlation COVID-19 COVID-19 patients Critically ill Critically ill patient critically ill patients Cytokine response syndrome decrease defined disease severity fibrinogen Follow-up had more Hospitalization Hospitalized hospitalized COVID-19 patient IL-10 IL-2 receptor IL-6 IL-8 increase in increased mortality independent Inflammation Injury International laboratory-confirmed longitudinal marker mechanical ventilation Mortality multiorgan failure non-critically ill patient non-survivor Non-survivors nonspecific normalized occur outcome Patient poor prognosis positive correlation quartile reported Result sensitivity Shock survivor timepoint Tongji Hospital tumor necrosis factor-α upper reference limit women Wuhan, China [DOI] 10.1016/j.yjmcc.2020.08.008 [Article Type] Research article
Antibody Kinetics and Response to Routine Vaccinations in Infants Born to Women Who Received an Investigational Trivalent Group B Streptococcus Polysaccharide CRM 197 -Conjugate Vaccine During Pregnancy조사 3가 그룹 B 연쇄상구균 다당류 CRM 197 -임신 중 접합 백신을 받은 여성에게서 태어난 영아의 항체 동역학 및 정기 예방 접종에 대한 반응Articles and Commentaries Published on 2017-12-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, 백일해, 파상풍, [키워드] age antenatal vaccination antibody antibody level antibody levels Birth capsular clinical clinically Combination detectable Diphtheria diphtheria toxoid disease dosage dosages dose during pregnancy elicited enrolled geometric mean geometric mean concentration group group B Streptococcus conjugate vaccine groups Haemophilus influenzae Haemophilus influenzae type b immune response immune responses Infant Infants invasive investigated Kinetics Maternal mother not affect pediatric Placebo placebo group pneumococcal pneumococcal vaccination Pregnancy Randomized receive Received recipients Registration response Result routine routine immunization serotype serotype-specific serotypes significantly higher single-center study Streptococcus Tetanus the placebo group timepoint transferred trivalent vaccination Vaccine were assessed women [DOI] 10.1093/cid/cix666 PMC 바로가기 [Article Type] Articles and Commentaries