Interplay between SARS-CoV-2 and the type I interferon response
SARS-CoV-2와 I형 인터페론 반응 간의 상호작용
Review
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus-2
addition
against SARS-CoV
animal models
antiviral molecules
boost
caused
cells
characterized
clinical trial
Combination
complex interplay
conserved
conserved IFN evasion strategies
contribute
coronavirus
coronavirus epidemic
Coronavirus-2
counteraction
COVID-19
COVID-19 pandemic
Cytokines
dendritic cells
early stage
early stages
Efficacy
exacerbated
form
highlighting
IFN
IFN treatment
IFN-I
IFN-I response
IFN-I treatment
IFN-Is
immune response
interferons
knowledge
mechanism
MERS
MERS-CoV
Middle East
Middle East respiratory syndrome
Middle East respiratory syndrome-related coronavirus
molecular mechanisms
outbreak
pDC-mediated IFN response
pDC-mediated IFN responses
pDCs
plasmacytoid dendritic cell
plasmacytoid dendritic cells
potential benefit
potential benefits
proinflammatory cytokines
respiratory
responsible
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2–infected cells
Severe acute respiratory syndrome
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus-2
spatiotemporal regulation
the disease
therapeutic
type I interferon
type I interferons
Viral
viral infection
while
[DOI] 10.1371/journal.ppat.1008737 PMC 바로가기 [Article Type] Review
[DOI] 10.1371/journal.ppat.1008737 PMC 바로가기 [Article Type] Review