Passivated Impedimetric Sensors for Immobilization-Free Pathogen Detection by Isothermal Amplification and Melt Curve Analysis등온 증폭 및 용융 곡선 분석에 의한 고정화 없는 병원체 검출을 위한 부동태화 임피던스 센서Article Published on 2022-04-202022-09-11 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis Automation Clinical diagnosis complexity Curve detection Diagnosis diagnostic driven by false impedance increase isothermal amplification Laboratory LAMP Loop-mediated isothermal amplification Melt melt curve analysis microheating MONITOR pathogen detection POC point-of-care raise reduce robust SARS-CoV-2 pandemic Scaling sensor significantly true-positive Validity virus virus detection [DOI] 10.3390/bios12050261 PMC 바로가기 [Article Type] Article
First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine Research Published on 2022-04-192022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome Amino acid anti-viral response Asymptomatic Bacterial cellular coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patients cytokine profile dendritic cell disease Donor effective Efficacy effort elicit elicited epitope experiment Health Human humoral immune responses immune response Immunity in vivo indicated introduced negative control NTD NTD domain pathogen peptide peptide-based vaccine performed positive control predominant Protein provided Receptor binding domain Research SARS-CoV-2 SARS-CoV-2 vaccine subjects tested the Spike the vaccine Vaccine vaccine candidate Vaccines Validity volunteers [DOI] 10.1038/s41598-022-09615-w [Article Type] Research
WHO Standards-based questionnaire to measure health workers’ perspective on the quality of care around the time of childbirth in the WHO European region: development and mixed-methods validation in six countriesArticle Published on 2022-04-082022-10-05 Journal: BMJ Open [Category] 임상, [키워드] acceptability alpha value Care change changes in conducted country DelPhi economics English European Evidence finding French Future Health health worker hypothesised IMPROVE internal consistency Italian measure neonatology Newborn obstetrics participant Perspective physical Previous studies professional Quality quality in health care question questionnaire Region reliability resources Society Spanish Standard Swedish the WHO translate translated translation Validity were assessed WHO [DOI] 10.1136/bmjopen-2021-056753 PMC 바로가기 [Article Type] Article
Fostering compliance with physical distancing by interactive feedback in the context of the COVID-19 pandemic: A web-based randomized controlled trialResearch article Published on 2022-04-012022-10-05 Journal: Internet Interventions [Category] 임상, [키워드] Analysis Anxiety changes in Compliance conducted Containment measure control group COVID-19 Effect Evidence experiment experimental group Exploratory analysis Factor feedback Future help hygiene Infection Infectious disease information Intervention measure Measures objective pandemic participant physical distancing predicted Predictive Prevent prevention prevention of COVID-19 preventive measures Quantitative Randomized controlled trial receiving recognize reduced Result significantly higher Spread spread of COVID-19 subject tested Validity Visualization [DOI] 10.1016/j.invent.2022.100545 [Article Type] Research article
Treatment Adherence of Anti-TNF Drugs in the Patients with Inflammatory Bowel Disease: A Scale Development StudyOriginal Article Published on 2022-04-012024-09-04 Journal: The Turkish journal of gastroenterology : the official journal of Turkish [Category] 대상포진, [키워드] Anti-TNF alpha IBD reliability Scale development Treatment compliance Validity [DOI] 10.5152/tjg.2022.211170 PMC 바로가기 [Article Type] Original Article
Should samples be weighted to decrease selection bias in online surveys during the COVID-19 pandemic? Data from seven datasetsResearch Published on 2022-03-062022-10-28 Journal: BMC Medical Research Methodology [Category] Coronavirus, Fulltext, MERS, SARS, [키워드] adjust adopted age age and gender Analysis applied association bias collected COVID-19 COVID-19 pandemic cross-sectional survey dataset datasets decrease ENhance feature Gender highest independent variables initial measure not affect Online surveys pandemic regression analysis Relative difference Research Result Sample size selected selection bia Seven similarity Sociodemographic supplementary material to define triggered Validity variables was related Weighting [DOI] 10.1186/s12874-022-01547-3 PMC 바로가기 [Article Type] Research
Computed tomography findings and prognosis in older COVID-19 patientsResearch Published on 2022-03-012022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] 95%CI Affect age calculated Chest CT chest CT scan chronic condition Cluster Clusters Computed tomography confounders consolidation COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity CT finding CT findings enrolled GGO hazard ratio hierarchical clustering hospitalized COVID-19 patients identify implication independent Mortality multicenter multivariable model Old Older older patient older patients Oldest patients Pleural pleural effusion Pneumonia Prevalence prevalent Prognosis prognostic Prognostic marker reflect Result risk of death SARS-CoV-2 severity stratified supplementary material the patient tomography Validity was performed X-ray computed [DOI] 10.1186/s12877-022-02837-7 PMC 바로가기 [Article Type] Research
Computed tomography findings and prognosis in older COVID-19 patientsResearch Published on 2022-03-012022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] 95%CI Affect age calculated Chest CT chest CT scan chronic condition Cluster Clusters Computed tomography confounders consolidation COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity CT finding CT findings enrolled GGO hazard ratio hierarchical clustering hospitalized COVID-19 patients identify implication independent Mortality multicenter multivariable model Old Older older patient older patients Oldest patients Pleural pleural effusion Pneumonia Prevalence prevalent Prognosis prognostic Prognostic marker reflect Result risk of death SARS-CoV-2 severity stratified supplementary material the patient tomography Validity was performed X-ray computed [DOI] 10.1186/s12877-022-02837-7 PMC 바로가기 [Article Type] Research
Development of a theory-informed questionnaire to assess the acceptability of healthcare interventionsResearch Published on 2022-03-012022-10-28 Journal: BMC health services research [Category] COVID-19, MERS, SARS, [키워드] acceptability affective applied Characteristics Coverage COVID-19 vaccine creating criteria develop development Effectiveness eight feedback first dose healthcare Healthcare intervention help identify implementation phase Intention Intervention outcome outcome measures participant Perspective Pre-validation methods problem provide questionnaire Questionnaire development Questionnaires receiving recipient recommendation reduced reduction Research researcher Result retrospective Self-efficacy Seven supplementary material the vaccine Theoretical framework Validity [DOI] 10.1186/s12913-022-07577-3 PMC 바로가기 [Article Type] Research
Antibody responses to SARS-CoV-2 nucleocapsid and spike proteins in hospitalized patients with COVID-19: A multicenter, retrospective, cross-sectional study in Japan코로나19로 입원한 환자의 SARS-CoV-2 뉴클레오캡시드 및 스파이크 단백질에 대한 항체 반응: 일본의 다기관, 후향적, 횡단면 연구Multicenter Study Published on 2022-03-012022-09-11 Journal: Respiratory investigation [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] amplification Anti-spike anti-spike protein IgG antibody antibody levels Antibody Response Antibody responses automated collected coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional detect Diagnosis early-stage COVID-19 examined gene amplification healthcare worker hospitalized patient IgG IgM IgM antibodies immune immune responses Immunoglobulin Japan multicenter negative controls peaked plateau Protein retrospective SARS-CoV-2 SARS-CoV-2 nucleocapsid sera Seroconversion Serological assay serological test serology Seropositivity serum sample serum samples significant difference specificity Spike protein statistically significant symptom onset total Ig Validity were used [DOI] 10.1016/j.resinv.2021.11.006 PMC 바로가기 [Article Type] Multicenter Study