SARS-CoV-2 Phylogenetic Analysis, Lazio Region, Italy, February–March 2020Dispatch Published on 2020-08-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analysis circulating clade coronavirus coronavirus disease COVID-19 effective Europe full genome sequence information Italy Lazio Phylogenetic Phylogenetic tree Region respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 strain Strains virus spread virus strain viruses [DOI] 10.3201/eid2608.201525 PMC 바로가기 [Article Type] Dispatch
Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage siteResearch Article Published on 2020-07-032022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] ACE2 affecting Analysis binding caused changes in clinical symptom co-expression codon usage Colon coronavirus COVID-19 COVID-19 dissemination COVID-19 patient distribution electrostatic Evolution expression FCS furin furin cleavage gene mutation Genome indicated kidneys liver mechanism Mild mild flu-like symptoms Mutation OC43 Patient SARS-CoV-2 SARS-CoV-2 evolution sequence Sequencing Subtypes suggested surface protein synonymous the SARS-CoV-2 virus virus strain Wuhan Zhejiang ZJ01 [DOI] 10.1080/22221751.2020.1781551 PMC 바로가기 [Article Type] Research Article
Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020Rapid Communication Published on 2020-03-192022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] antibodies clinical picture coronavirus coronavirus disease COVID-19 first symptoms Genome Humoral immunity IgG response immunofluorescence assay Laboratory microneutralisation test molecular neutralising antibody response nucleocapsid SARS-CoV-2 secondary case single nucleotide specific IgM Spike proteins virus strain western blotting whole-genome sequencing Wuhan [DOI] 10.2807/1560-7917.ES.2020.25.11.2000266 PMC 바로가기 [Article Type] Rapid Communication
Characterization and pathogenicity of Vero cell-attenuated porcine epidemic diarrhea virus CT strainResearch Published on 2019-10-282022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] amino acid change Antigen Attenuated vaccines attenuation caused Cell characterization Clinical symptoms cytopathic effects Epidemic epidemic diarrhea experiment Genome histopathological intestinal lesions passage pathogenicity PEDV Porcine epidemic diarrhea virus protective effect reductions in responsible Result Sequence analysis Strains survival rate vaccine strain variant Vero Vero Cell viral titer virulence virulent virus virus strain was obtained whole-genome sequencing [DOI] 10.1186/s12985-019-1232-7 PMC 바로가기 [Article Type] Research
Molecular detection of enteric viruses and the genetic characterization of porcine astroviruses and sapoviruses in domestic pigs from Slovakian farmsResearch Article Published on 2018-10-192022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] age circulating clinically collected diagnostic value diarrhea epidemic diarrhea European evaluate FIVE gastroenteritis Genetic genome sequence groups Health healthy Impact indicated Infection investigated less Lineage MOST no significant difference PEDV Phylogenetic analysis pig Porcine astrovirus Porcine sapovirus provide RdRP rectal swab Result risk sequence Slovakia strain TGEV virus virus strain [DOI] 10.1186/s12917-018-1640-8 PMC 바로가기 [Article Type] Research Article
Full-length genome sequences of porcine epidemic diarrhoea virus strain CV777; Use of NGS to analyse genomic and sub-genomic RNAsResearch Article Published on 2018-03-012022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] affected Analysis Cell culture characterized coding region coronavirus deletions determine diarrhoea disease Epidemic expression feature full-length genome gene product Genome genome sequence genomic highest infected cells Laboratory NGS ORF3 PEDV performed Point mutation predicted premature termination proportion protocols reference sequence RNA sequence Sequencing Spike protein sub-genomic mRNA Variability variant virus virus strain [DOI] 10.1371/journal.pone.0193682 PMC 바로가기 [Article Type] Research Article
Evaluation of the efficacy of a commercial inactivated genogroup 2b-based porcine epidemic diarrhea virus (PEDV) vaccine and experimental live genogroup 1b exposure against 2b challengeResearch Article Published on 2017-10-262022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] age Antibody Response Cluster condition detectable Efficacy epidemic diarrhea evidenced fecal FIVE groups IgA IgA level IgA response IgG level inactivated Inactivated vaccine intramuscular less Live virus log naïve pathogenic PEDV pig PROTECT randomly divided reduction RNA significantly higher significantly lower Vaccine viral shedding virus virus strain [DOI] 10.1186/s13567-017-0472-z PMC 바로가기 [Article Type] Research Article
Detection and phylogenetic analyses of spike genes in porcine epidemic diarrhea virus strains circulating in China in 2016–2017Short Report Published on 2017-10-102022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] addition Amino acid Analysis analyzed Characteristics China Chinese circulating classical collected Complete contribute detection diarrhea epidemic diarrhea Epidemiology gastroenteritis Genetic genetic diversity Hainan identity indicated insertion island knowledge Molecular epidemiology nucleotide outbreak Pathogens PCR PEDV Phylogenetic analysis Porcine deltacoronavirus positive Result S gene sequenced Sequencing spike gene strain TGEV the epidemic the vaccine vaccine strain virulent virus virus strain [DOI] 10.1186/s12985-017-0860-z PMC 바로가기 [Article Type] Short Report
Cross protective immune responses in nursing piglets infected with a US spike-insertion deletion porcine epidemic diarrhea virus strain and challenged with an original US PEDV strainShort Report Published on 2017-10-062022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] antibody secreting cells cross-protective immunity diarrhea epidemic diarrhea IgA ileal inoculated investigated Neutralizing antibody titer PEDV protective immune response protective immunity serum virus virus strain [DOI] 10.1186/s13567-017-0469-7 PMC 바로가기 [Article Type] Short Report
Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strainsReview Published on 2016-06-082022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] aa, amino acid addition America Analysis antigenic antigenic variation antigenicity Asia Asian CCIF, cell culture immunofluorescence assay CDCD, cesarean-derived, colostrum-deprived contagious contribute coronavirus cross-protection cross-reactivity DPI, days post-inoculation E, Envelope ELISA, enzyme-linked immunosorbent assay epidemic diarrhea Europe Evolution example feature FIPV, feline infectious peritonitis virus Genetic Health HPI, hours post-inoculation IFN, interferon IHC, immunohistochemistry in vivo INDEL, insertions and deletions information less M, membrane mAb, monoclonal antibody molecular mechanism morbidity and mortality N, nucleocapsid nt, nucleotide NTD, N-terminal domain ORF, open reading frame other coronavirus outbreak Pathogenesis pathogenicity pathologic feature PDCoV, porcine deltacoronavirus PED, porcine epidemic diarrhea PEDV PEDV, porcine epidemic diarrhea virus PFU, plaque-forming unit populations Porcine epidemic diarrhea Porcine epidemic diarrhea virus PRCV, porcine respiratory coronavirus RBD, receptor binding domain resulting S, spike sequence strain Strains TC, tissue culture-adapted TCID50, 50% tissue culture infectious dose TGEV, transmissible gastroenteritis virus threat US, United States Vaccine vaccine strain variant variants VH:CD, villus height versus crypt depth ratio virulence virus virus strain VN, viral neutralization WT, wild type [DOI] 10.1016/j.virusres.2016.05.023 PMC 바로가기 [Article Type] Review