Robustness analysis for quantitative assessment of vaccination effects and SARS-CoV-2 lineages in Italy이탈리아에서 백신 접종 효과 및 SARS-CoV-2 계통의 정량적 평가를 위한 강건성 분석Article Published on 2022-04-292022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] Affect Algorithm Analysis analyzed Asymptomatic avoidance Bayesian booster vaccination booster vaccinations calibrated calibration characterized Conditional robustness analysis Contact tracing Containment contributed COVID-19 CRA diffusion Effect effective vaccine Effective vaccines Effectiveness Efficacy Epidemic hospital identify impair Intervention Italian Italy lineages long term measure Mitigation ODE model. pandemic parameter parameters Policy quantitative assessment reveal robustness SARS-CoV-2 SARS-CoV-2 lineage SEIR Spread the epidemic Transmission vaccination vaccination rate Vaccinations Vaccine vaccine efficacy Vaccines variant variants variants of SARS-CoV-2 virus transmission waning immunity [DOI] 10.1186/s12879-022-07395-2 PMC 바로가기 [Article Type] Article
Characterization of immune responses in fully vaccinated individuals after breakthrough infection with the SARS-CoV-2 delta variantSARS-CoV-2 델타 변이체에 의한 돌발성 감염 후 백신을 완전히 접종한 개인의 면역 반응 특성화Article Published on 2022-04-202022-09-11 Journal: Science Translational Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anamnestic antibody Antibody Response Antibody titers binding antibody Breakthrough infection breakthrough infections CD8 characterization Cluster Combination coronavirus demonstrated immune response individual Infection Massachusett Massachusetts mucosal nasal Neutralizing antibody titer neutralizing antibody titers Peripheral blood population immunity positive reported respiratory robust SARS-CoV-2 secretion serum antibody serum antibody response severe acute respiratory syndrome Coronavirus Spike protein T cell T cell response T cell responses tested the SARS-CoV-2 These data vaccinated individual vaccinated individuals vaccination variant variants waning immunity widespread [DOI] 10.1126/scitranslmed.abn6150 PMC 바로가기 [Article Type] Article
Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting전국적인 환경에서 BNT162b2 mRNA 코비드-19 백신의 4차 접종Comparative Study Published on 2022-04-132022-09-25 Journal: The New England Journal of Medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome age analyzed B.1.1.529 BNT162b2 vaccine booster dose Care clinical variables collaboration coronavirus coronavirus disease country death dose doses driven by effective Effectiveness estimate evaluate evaluated Evidence family Francesca Harvard Medical School Health Hospitalization Infection mRNA of BNT162b2 Older outcome outcomes Poisson regression primary analysis recorded reducing relative Result risk SARS-CoV-2 SARS-COV-2 infection Sensitivity analyses sensitivity analysis setting Sociodemographic symptomatic COVID-19 two group Vaccine vaccine dose variant waning immunity was performed [DOI] 10.1056/NEJMoa2201688 PMC 바로가기 [Article Type] Comparative Study
Outbreak of SARS-CoV-2 B.1.617.2 (delta) variant in a nursing home 28 weeks after two doses of mRNA anti-COVID-19 vaccines: evidence of a waning immunitymRNA 항-COVID-19 백신 2회 접종 후 28주 만에 요양원에서 SARS-CoV-2 B.1.617.2(델타) 변종 발생: 면역 약화의 증거Article Published on 2022-04-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 48 hour 48 hours 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Anti-spike anti-Spike IgG Antibody Units B.1.617.2 B.1.617.2 SARS-CoV-2 variant binding antibody unit booster dose collected coronavirus coronavirus disease Coronavirus disease 2019 Coverage COVID-19 Delta diagnosed dose Effectiveness Evidence expressed Fisher exact test health worker health workers higher risk IgG Immunity index case Infection Italy Lineage material mRNA mRNA vaccine Neutralizing nursing home nursing home residents outbreak Quantitative Relative risk resident respiratory resulting risk RT-PCR SARS-CoV-2 SARS-COV-2 infection second dose Sequencing sera serum severe acute respiratory syndrome Coronavirus severe coronavirus disease severe COVID-19 severe disease titre vaccination Vaccine vaccine effectiveness variant waning immunity was determined was measured was performed WHO [DOI] 10.1016/j.cmi.2021.12.013 PMC 바로가기 [Article Type] Article
Third dose of SARS-CoV-2 vaccination in hemato-oncological patients and health care workers: immune responses and adverse events – a retrospective cohort study혈액종양 환자 및 의료 종사자에 대한 SARS-CoV-2 백신 3차 접종: 면역 반응 및 부작용 - 후향적 코호트 연구Article Published on 2022-04-012022-09-11 Journal: European journal of cancer (Oxford, England : 1990 [Category] COVID19(2023년), SARS, 변종, [키워드] Adverse adverse event adverse events Analysis anti-S anti-SARS-CoV-2 antibody antibody levels B cell Cancer Care CD19 CD19+ CD56 CD56+ Cell chills Community community hospital Control correlated COVID-19 decrease dose event fatigue follow-up study haematological malignancies haematological malignancy HCW Health Health care Health care worker hospital immune response increasingly Italy local pain longitudinal longitudinal analysis Lower malignancy NK cell oncology other treatment other treatments Patient Patients with cancer patients with haematological Peripheral blood Questionnaires receiving retrieved retrospective cohort study SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccination second vaccination Side-effect solid tumour Spike protein therapy trials Tumours vaccination virus variant waning immunity [DOI] 10.1016/j.ejca.2022.01.019 PMC 바로가기 [Article Type] Article
Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study다양한 COVID-19 예방 접종 범위 수준을 달성하기 전후에 안면 마스크 사용 유지: 모델링 연구Article Published on 2022-04-012022-09-11 Journal: The Lancet. Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] added Advancing agency B.1.617.2 center city Coverage COVID-19 COVID-19 pandemic COVID-19 vaccination decrease Effectiveness experiment face Face mask Face masks Factor Final foundation increase maintain maintaining many case many cases Medical Sciences New York not used omicron Omicron variant per day Perspective provide provided Quality question raised reduce Relaxation representing required SARS-CoV-2 saving Science Simulation social interaction Spread summer Support Transmissibility university USA vaccination Vaccine variant variants virus waning immunity were used Winter [DOI] 10.1016/S2468-2667(22)00040-8 PMC 바로가기 [Article Type] Article
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factorsSARS-CoV-2 백신 접종 후 면역 약화 및 영향 요인 모델링Article Published on 2022-03-282022-09-12 Journal: Nature Communications [Category] MERS, SARS, 진단, [키워드] age antibody Antibody Response BNT162b2 vaccine ChAdOx1-nCoV19 Combination correlated COVID-19 cubic spline decrease determine dose examined Factor first dose Generalized IgA IgA response IgG IgG antibody IgG level Immunity Infection initial Injections knowledge modeling mounted natural infection of BNT162b2 responses SARS-CoV-2 SARS-CoV-2 vaccination second dose Sex significantly suggested T-cell T-cell Response Vaccine waning immunity were used [DOI] 10.1038/s41467-022-29225-4 PMC 바로가기 [Article Type] Article
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in miceResearch Article Published on 2022-03-222022-10-04 Journal: Science Translational Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 치료제, [키워드] acute respiratory syndrome administration Antiviral antiviral activity antivirals approval Breakthrough infection conserved coronavirus coronavirus disease CoV COVID-19 Culture description develop dose-dependent drug effective EUA exhibited GS-441524 in vitro in vivo increasingly infected with SARS-CoV-2 Infection lung lung cell lung cell line MERS-CoV mice Middle East molnupiravir monoclonal antibodies neutralization outpatients pandemic parent nucleoside parental pharmacokinetic Protective Pulmonary function reduced Remdesivir respiratory RNA-dependent RNA polymerase Safe SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2 variant Support target therapeutic therapeutic efficacy translated Treatment vaccination Vaccines Viral load Viral protein virus waning immunity [DOI] 10.1126/scitranslmed.abm3410 PMC 바로가기 [Article Type] Research Article
Timely Monitoring COVID-19 Vaccine Protection, Berlin, Germany, April 15th to December 15th, 2021시기 적절한 모니터링 COVID-19 백신 보호, 독일 베를린, 2021년 4월 15일~12월 15일Article Published on 2022-03-212022-09-11 Journal: International Journal of Public Health [Category] SARS, 변종, [키워드] Abstract Berlin booster booster vaccination COVID-19 Germany monitoring protection SARS-CoV-2 SARS-CoV-2 variants Surveillance Vaccine vaccine effectiveness vaccine protection Vaccines waning immunity [DOI] 10.3389/ijph.2022.1604633 PMC 바로가기 [Article Type] Article
Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infectionsSARS-CoV-2 백신 접종 후 지속적인 B 세포 기억은 돌발성 감염 동안 기능합니다Article Published on 2022-03-092022-09-12 Journal: Cell Host & Microbe [Category] MERS, SARS, 진단, [키워드] antibody Antigen B cell memory BNT162b2 mRNA vaccine Breakthrough infection breakthrough infections clinical disease Cohort COVID-19 expected functional had no HCW HCWs Health care worker IgA immunization in vivo induce investigated memory B memory B cell memory B cells mRNA mRNA vaccine mucosal mucosal immunity outcome persistent physiological produced producing Saliva salivary salivary IgA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2-specific antibodies second dose serum specific antibody vaccinated individual waning immunity while [DOI] 10.1016/j.chom.2022.01.003 PMC 바로가기 [Article Type] Article