Colonic Epithelial Angiotensin-Converting Enzyme 2 (ACE2) Expression in Blacks and Whites: Potential Implications for Pathogenesis Covid-19 Racial Disparities흑인과 백인의 결장 상피 안지오텐신 전환 효소 2(ACE2) 발현: 발병 원인 Covid-19 인종 격차에 대한 잠재적 의미Article Published on 2022-04-012022-09-11 Journal: Journal of racial and ethnic health disparities [Category] Coronavirus, COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE2 Actin age Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Beta beta-actin biopsy black BMI cell receptor Chain Reaction concert correlation COVID-19 COVID-19 infections Cytokine storm disparity downregulation epithelial epithelial cell expression fold GAPDH Gender host protein immune response Infection Inflammation Inflammatory response knowledge mechanism Mortality mRNA mucosal multivariable multivariable analyses multivariable analysis neoplasia normalization not altered Perspective polymerase chain polymerase chain reaction Potential protease Racial Racial disparities real-time polymerase chain reaction rectal mucosa Serine serine 2 severity statistical significance suppress susceptibility targets TMPRSS2 TMPRSS2 level TMPRSS2 levels TMRPSS2 Total transmembrane transmembrane protease serine 2 univariable was performed were used white [DOI] 10.1007/s40615-021-01004-9 PMC 바로가기 [Article Type] Article
QCovSML: A reliable COVID-19 detection system using CBC biomarkers by a stacking machine learning modelResearch article Published on 2022-04-012022-10-05 Journal: Computers in biology and medicine [Category] 바이오마커, 치료기술, [키워드] Accuracy age approach AUC average Biomarker blood cell count CBC Cohort collected complete blood count Complete blood count (CBC) coronavirus disease country COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 patients cut-off value dataset datasets demonstrated detection detection system equipment evaluate external validation false-negative rate FIVE Generalizability gold standard Hospital admission Italy less lymphocyte machine learning classifiers monocyte parameter Patient positive Precision predict produced Raphael robust RT-PCR scoring system sensitivity Seven specificity Stacking machine learning the patient was used were used white [DOI] 10.1016/j.compbiomed.2022.105284 [Article Type] Research article
Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection바이러스성 호흡기 감염에서 박테리아를 구별하기 위한 신속한 숙주 유전자 발현 검사의 전향적 검증Multicenter Study Published on 2022-04-012022-09-11 Journal: JAMA Network Open [Category] 유전자 메커니즘, 진단, [키워드] 95% CI absence acute COVID-19 acute respiratory illness age Analysis antibacterial therapy antibiotic ARI Asian Bacterial Bacterial infection black Care cause Characteristics children clinical clinically Cohort Concordance diagnostic Emergency Departments enrolled Enrollment entire cohort Ethnicity expression febrile female followed by group groups Hispanic Host host gene host gene expression host response IMPROVE individual IQR less likelihood male median age Messenger RNA multicenter Native Negative predictive value NPV offer outcome outcomes participant Participants pathogen Patient patients with ARI patients with COVID-19 performance Positive predictive value Predictive value primary analysis Probability procalcitonin Prospective quantified Rapid reported respiratory Respiratory illness resulting sensitivity specificity stratified Test the median validation Viral viral infection white with COVID-19 [DOI] 10.1001/jamanetworkopen.2022.7299 PMC 바로가기 [Article Type] Multicenter Study
Mindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical TrialRandomized Controlled Trial Published on 2022-04-012022-10-05 Journal: JAMA Internal Medicine [Category] 임상, [키워드] 95% CI age Asian assessment attrition baseline black caused chronic clinical clinics control condition COVID-19 pandemic defined demonstrated distress dose drug ecological Efficacy emotional enhancement enrolled evaluate Follow-up follow-up period functional greater group guideline Hispanic improvement index Intervention inventory IQR Latino medications Mindfulness-based misuse Odds ratio opioid outcome Pain participant Patient positive primary care Randomized randomized clinical trial receiving reduced reducing reduction reduction in reductions in secondary severity subscale score sustained Symptom the mean Therapies therapy Treatment Urine Utah white women [DOI] 10.1001/jamainternmed.2022.0033 PMC 바로가기 [Article Type] Randomized Controlled Trial
Use of At-Home COVID-19 Tests – United States, August 23, 2021-March 12, 2022재택 COVID-19 테스트 사용 - 미국, 2021년 8월 23일-2022년 3월 12일Article Published on 2022-04-012022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] COVID19(2023년), SARS, 변종, [키워드] age Antigen antigen tests assist B.1.1.529 B.1.617.2 black cause confirmation COVID-19 COVID-19 testing cross-sectional Delta demographic characteristics diagnostic Disease prevalence England Geography Health help High School identify incidence increasingly Infection information Isolation less Measures New nucleic acid nucleic acid amplification omicron Population Positive test preventative measure preventative measures provide quarantine reduce reported SARS-CoV-2 SARS-COV-2 infection School South spread of COVID-19 Symptom Test the SARS-CoV-2 Transmission United States variant virus were used West white [DOI] 10.15585/mmwr.mm7113e1 PMC 바로가기 [Article Type] Article
COVID-19-Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status – COVID-NET, 14 States, July 2021-January 2022인종/민족 및 예방 접종 상태별 SARS-CoV-2 Delta 및 Omicron 변종 우세 기간 동안 성인 중 COVID-19 관련 입원 - COVID-NET, 14개 주, 2021년 7월-2022년 1월Article Published on 2022-03-252022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 변종, [키워드] accounted Adults analyzed Awareness B.1.1.529 B.1.617.2 benefit black booster cause circulating circulation COVID-19 COVID-19 vaccination COVID-19 vaccinations COVID-19 vaccine COVID-19 vaccines Delta dose ethnic group highest Hospitalization hospitalizations Hospitalized Implementing network omicron pandemic peaked predominant proportion public health Racial raising reduce remained risk SARS-CoV-2 sequenced status the United State United States vaccination Vaccination Status Vaccinations Vaccine variant variant of SARS-CoV-2 virus white with COVID-19 [DOI] 10.15585/mmwr.mm7112e2 PMC 바로가기 [Article Type] Article
Relationship between mask wearing, testing, and vaccine willingness among Los Angeles County adults during the peak of the COVID-19 pandemicCOVID-19 전염병이 정점에 달했을 때 로스앤젤레스 카운티 성인의 마스크 착용, 테스트 및 백신 의지 사이의 관계Article Published on 2022-03-172022-09-11 Journal: Translational behavioral medicine [Category] SARS, 변종, [키워드] adopted Adults African African American Asian association Behavior being Care conditions conducted COVID-19 COVID-19 pandemic COVID-19 test COVID-19 testing COVID-19 vaccine Critical cross-sectional survey demographic characteristics Encouraging Face mask Factor female Health Health care health condition Height higher education highest Hospitalized include individual less logistic regression model logistic regression models Los Angele Los Angeles Mask mask wearing measure men mitigate new virus pandemic performed platform populations PROTECT Protective receive reducing relationship reported resident risk Risk factors Spread survey Testing Transmission vaccination vaccination rate Vaccine variant white with COVID-19 [DOI] 10.1093/tbm/ibab150 PMC 바로가기 [Article Type] Article
Association of COVID-19 Vaccination With Symptomatic SARS-CoV-2 Infection by Time Since Vaccination and Delta Variant Predominance예방 접종 후 경과 시간에 따른 COVID-19 예방 접종과 증상 SARS-CoV-2 감염의 연관성 및 델타 변이형 우세Article Published on 2022-03-152022-09-11 Journal: JAMA [Category] SARS, 변종, [키워드] 95% CI access Ad26 Ad26.COV2.S Adults amplification Analysis association attenuation BNT162b2 Case-control Control COVID-19 COVID-19 testing COVID-19 vaccination COVID-19 vaccine Delta delta variant dose doses Effectiveness estimate greater increase in Increasing initial measure monitoring mRNA mRNA vaccination mRNA-1273 multivariable logistic regression NAAT nucleic acid nucleic acid amplification tests Odds ratio of BNT162b2 Older outcome platform receipt SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleic acid second dose significantly symptomatic infection symptomatic SARS-CoV-2 infection Testing time vaccination Vaccine variant white [DOI] 10.1001/jama.2022.2068 PMC 바로가기 [Article Type] Article
Reasons for COVID-19 vaccine refusal among people incarcerated in Canadian federal prisonsResearch Article Published on 2022-03-092022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] benefit Canada Care conducted COVID-19 COVID-19 vaccine expressed Factor Health Health care Hesitancy highest identify incarcerated Intervention lack lower risk median Misconception Model participant proportion Purposive sampling reason refusal reported representing Result risk thematic analysis transcript Universal vaccination Vaccine Vaccine hesitancy white [DOI] 10.1371/journal.pone.0264145 PMC 바로가기 [Article Type] Research Article
Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east LondonArticle Published on 2022-03-082022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료법, [키워드] Admission age Analysis Asian association black changes in COVID-19 COVID-19 infection COVID-19 treatments death distribution Epidemiology ethnic group Ethnic groups greater hospital Hospital admission hospitalisation hospitalised patient increased risk Infectious diseases Local London Mortality multivariable analysis NHS outcome pandemic Patient Patient care patients Population public health relative risk factor Risk factors risk of COVID-19 risk of death SARS-COV-2 infection second wave Sex significantly higher Socioeconomic deprivation survival was used white [DOI] 10.1038/s41598-022-07532-6 PMC 바로가기 [Article Type] Article