Human Body Performance with COVID-19 Affectation According to Virus Specification Based on Biosensor Techniques바이오센서 기법을 기반으로 한 바이러스 사양에 따른 COVID-19 영향에 따른 인체 성능Review Published on 2021-12-152022-09-10 Journal: Sensors (Basel, Switzerland) [Category] SARS, 치료기술, [키워드] analyzed biosensor biosensor application Body category change coronavirus detection COVID-19 COVID-19 detection COVID-19 diagnosis CRISPR disease effort Fecal–oral transmission Human human body human nature LAMP life next generation sequencing (NGS) NGS optical outbreak performance researcher respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 virus specification technique Transmission transmission human exchange vertical vertical transmission virus virus spread with COVID-19 worldwide pandemic Wuhan Wuhan, China [DOI] 10.3390/s21248362 PMC 바로가기 [Article Type] Review
Inflammasomes and SARS-CoV-2 InfectionReview Published on 2021-12-142022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] “cytokine storm” activate Activation Adaptive immune response affected caused coronavirus COVID-19 COVID-19 patient Cytokines develop disease form function gasdermin D IL-18 IL-1β induce Inflammasome inflammasomes Inflammatory cell death influenza A virus innate immune response innate immune system Innate immunity Local majority mild respiratory symptoms mRNA vaccine multiple organ people with COVID-19 pro-inflammatory cytokine pro-inflammatory cytokines Protective Protein protein complex pyroptosis recent SARS-CoV-2 SARS-COV-2 infection secretion severe COVID-19 severe disease Structure systemic inflammation virus infection worldwide pandemic [DOI] 10.3390/v13122513 PMC 바로가기 [Article Type] Review
Novel coronavirus pathogen in humans and animals: an overview on its social impact, economic impact, and potential treatments인간과 동물의 신종 코로나바이러스 병원체: 사회적 영향, 경제적 영향 및 잠재적 치료법에 대한 개요Review Published on 2021-12-012022-09-11 Journal: Environmental science and pollution research inter [Category] SARS, 유전자 메커니즘, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animals caused coronavirus coronavirus disease CoV COVID-19 COVID-19 mortality deaths Economy emerging pathogens exceeded Health Health Organization Human human pathogen humans Infection international public health lethal disease lockdowns measure mechanism MERS Middle East Middle East respiratory syndrome movement National novel Novel coronavirus outbreak pandemic pandemic of COVID-19 pathogen pathogenicity Pathogens Potential Potential treatment SARS-CoV SARS-CoV-2 SARS-CoV-2 virus Sequencing severe acute respiratory syndrome Coronavirus Social impact. spread to Symptoms syndrome therapy for COVID-19 Transmission Travel viral disease WHO World Health Organization worldwide pandemic [DOI] 10.1007/s11356-021-16809-8 PMC 바로가기 [Article Type] Review
Analysis of 329,942 SARS-CoV-2 records retrieved from GISAID databaseGISAID 데이터베이스에서 검색된 329,942개의 SARS-CoV-2 기록 분석Article Published on 2021-12-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 변종, 치료기술, [키워드] addressed age Analysis B.1.1.7 B.1.1.7 variant bioinformatics caused Cluster Clustering Completeness conserved coronavirus correlation coefficient Correlation coefficient matrix Deletion deletions Denmark Gender genetic variability Genome genomes GISAID GISAID database greater Health Science hidden less machine machine learning material Mutation nucleotide nucleotides ORF1ab ORF6 pandemic Patient performed proportion Research retrieved SARS-CoV-2 SARS-CoV-2 virus sequence Sequence alignment sequences Sequencing SNP suggested variant was performed were excluded worldwide pandemic [DOI] 10.1016/j.compbiomed.2021.104981 PMC 바로가기 [Article Type] Article
A method for the identification of COVID-19 biomarkers in human breath using Proton Transfer Reaction Time-of-Flight Mass SpectrometryResearch paper Published on 2021-11-202022-10-04 Journal: EClinicalMedicine [Category] 바이오마커, [키워드] Accuracy age Analysis analyzed approach Biomarker breath caused collected COVID-19 COVID-19 infection develop evaluated finding groups hospital introduced machine learning models mass positive positive sample predicted produced proton reaction sensitivity spectrometer Spectrometry subject USA virus was used worldwide pandemic [DOI] 10.1016/j.eclinm.2021.101207 PMC 바로가기 [Article Type] Research paper
In Silico End-to-End Protein-Ligand Interaction Characterization Pipeline: The Case of SARS-CoV-2In Silico 종단 간 단백질-리간드 상호 작용 특성 분석 파이프라인: SARS-CoV-2 사례Article Published on 2021-11-192022-09-11 Journal: ACS synthetic biology [Category] SARS, 치료제, [키워드] atomic level AutoDock AutoDock vina characterization complex conformational COVID-19 Data analysis database disease docking Dynamics effective Gromacs guideline HADDOCK help homology in silico include inhibitor Interaction Interpretation M pro methodology molecular molecular docking molecular dynamics molecular dynamics simulations pandemic disease problem protease protein-ligand protocol provided PyMol robust SARS-CoV-2 SARS-CoV-2 main protease target three-dimensional structure Treatment triggered urgency Viral proteins Virtual screening were used worldwide pandemic [DOI] 10.1021/acssynbio.1c00368 PMC 바로가기 [Article Type] Article
Effective Prophylaxis of COVID-19 in Rhesus Macaques Using a Combination of Two Parenterally-Administered SARS-CoV-2 Neutralizing Antibodies2개의 비경구 투여 SARS-CoV-2 중화 항체의 조합을 사용하여 붉은털 원숭이에서 COVID-19의 효과적인 예방Cellular and Infection Microbiology Published on 2021-11-182022-09-12 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단, [키워드] accelerate added Administered administration anti-SARS-CoV-2 antibody combination benefit beta coronavirus block blocking clinical study Cohort Combination combination treatment Complete COVID-19 disease dose effective evidenced immunoprophylaxis Infection lack lower dose mAb macaque monoclonal antibody mucosal neutralize nonhuman primates parenteral administration pathogenic pathologic pathology pharmacokinetics prophylactically Protective receiving Result rhesus SARS-CoV-2 SARS-CoV-2 antibodies subset swabs tissue viral challenge viral infection virus Virus neutralization worldwide pandemic [DOI] 10.3389/fcimb.2021.753444 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Blood Purification in Severe and Critical COVID-19 Patients: A Case Series of 5 PatientsPublic Health Published on 2021-11-172022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Acute kidney injury acute respiratory syndrome age AKI ameliorated analyzed blood gas analysis Blood purification BNP boost Brain caused Characteristics clinical Complication complications Concentration Continuous coronavirus coronavirus disease COVID-19 Critical critical COVID-19 patients discharged disease early stage evaluate the effect Fluid management hemodiafiltration hemofiltration HFNC hospital ICU Identifier IL-6 Inflammatory cytokine Inflammatory cytokine storm intensive care interferon-alpha interleukin-6 Laboratory lactate dehydrogenase LDH lymphocyte male measure nasal NIV non-invasive ventilation oxygen Oxygenation oxygenation index patients patients with COVID-19 peptide progression purification SARS-CoV-2 Serum level Sery Shock significantly Standard of care supportive care survived Symptom therapy TNT transferred Treatment university Ventilation were recorded worldwide pandemic [DOI] 10.3389/fpubh.2021.741125 PMC 바로가기 [Article Type] Public Health
Jeopardy of COVID-19: Rechecking the Perks of Phytotherapeutic InterventionsCovid-19의 위태로움 : 식물성 요법의 특전 재발Review Published on 2021-11-102022-08-31 Journal: Molecules [Category] MERS, SARS, 신약개발, [키워드] acute kidney angiotensin angiotensin converting enzyme Angiotensin converting enzyme-2 anti-inflammatory activity antioxidant antiviral activities antiviral activity attachment can be used chemical structures clinical complication clinical status Combination Complication coronavirus disease country COVID-19 deteriorate disease Diseases drug effective encapsulation environmental stress focus Health Health crisis help Immunity implication IMPROVE increase in infected patients Inflammation inhibit Kidney disease knowledge lack Liver disease medicinal plants metabolite neurological Novel coronavirus novel coronavirus disease nutrition oxidative stress pharmacological phytotherapy plant plants Prophylactic protease provide reason reason for Replication respiratory SARS-CoV-2 Serine Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 Side effect signaling molecule signaling molecules spike glycoprotein structures therapeutic transmembrane serine protease transmembrane serine protease 2 unique virus viruses worldwide pandemic [DOI] 10.3390/molecules26226783 PMC 바로가기 [Article Type] Review
Aerosol delivery systems for treating obstructive airway diseases during the SARS-CoV-2 pandemicSARS-COV-2 전염병 중 폐쇄성기도 질환 치료를위한 에어로졸 전달 시스템Review Published on 2021-11-012022-08-31 Journal: Internal and Emergency Medicine [Category] MERS, SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol airway Alter alternative benefit cause caused coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patients disease dose droplet droplets Evidence Guidance Health crisis healthcare in some increased risk Infection Inhaled inhaler inhalers measure nebulisation Nebuliser nebulisers Obstructive outbreak pandemic Patient patients with COVID-19 potential risk produced public health crisis regimens respiratory respiratory droplet risk SARS-CoV-2 SARS-CoV-2 pandemic severe acute respiratory syndrome Coronavirus sneeze switch the SARS-CoV-2 Therapies therapy Transmission transmission of SARS-CoV-2 Treatment Viral Viral transmission virus worldwide pandemic [DOI] 10.1007/s11739-021-02812-x PMC 바로가기 [Article Type] Review