A doubt of multiple introduction of SARS-CoV-2 in Italy: A preliminary overview이탈리아에서 SARS-CoV-2의 다중 도입에 대한 의심: 예비 개요Article Published on 2020-09-012022-09-11 Journal: Journal of medical virology [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed attenuate Betacoronavirus circulating clinical samples Complete coronavirus country COVID-19 Diseases dissemination Epidemic Epidemics Epidemiology Genome genomic genomic sequence help impair IMPROVE Infectious diseases information Italian Italian outbreak Italy novel Betacoronavirus Phylogenetic phylogenetic inference phylogenetic inference. public health raised respiratory SARS-CoV-2 SARS-CoV-2 isolates severe acute respiratory syndrome Coronavirus Surveillance the SARS-CoV-2 virus [DOI] 10.1002/jmv.25773 PMC 바로가기 [Article Type] Article
Stigma and Discrimination (SAD) at the Time of the SARS-CoV-2 PandemicReview Published on 2020-08-312022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] Analysis avoiding behaviors Care contagious diseases COVID-19 discrimination disease Diseases dissemination emergency response epidemic outbreak evaluate group HCV Health indicate Infectious disease intervene Intervention knowledge measure observé outbreak pandemic pandemic outbreak promote Psychological public health public health measure reduce Research risk SARS-CoV-2 SARS-COV-2 infection Spread Stigma the SARS-CoV-2 time Tuberculosis with HIV Zika [DOI] 10.3390/ijerph17176341 PMC 바로가기 [Article Type] Review
Hydroxychloroquine plus personal protective equipment versus standard personal protective equipment alone for the prevention of COVID-19 infections among frontline healthcare workers: the HydrOxychloroquine Prophylaxis Evaluation(HOPE) trial: A structured summary of a study protocol for a randomized controlled trialLetter Published on 2020-08-312022-10-29 Journal: Trials [Category] COVID-19, MERS, [키워드] 1:1 absolute reduction addition Administered Admission adverse event adverse events all-cause mortality allocation Arm ARMS assigned assumed baseline Bia breast-feeding China clinical Combination Compliance conducted Confirmed COVID-19 infection Contamination COVID-19 COVID-19 infection Date detect dissemination dose ECG element eligible end point enrolled enrolment evaluate evaluate the effect excluded Follow-up frontline healthcare worker greater HCQ HCW HCWs Health personnel healthcare hospital Hospitalization hospitals Hydroxychloroquine ICU India Infection infection rate initiated intensive care Intervention intervention arm invasive ventilation investigator Italy Laboratory Loading dose medication MONITOR Non-invasive number objective Open-label organ support outcome parallel group participant Patient performed Personal protective equipment PPE pregnant Prevent prevention of COVID-19 Primary outcome proportion protocol provided QT prolongation QTc randomisation randomised randomised controlled trial randomization Randomized controlled trial rate of infection readmission receive reduction Registered registry renal replacement therapy reported Research Sample size Secondary outcomes secure Standard Statistical power status stratified Study protocol Treatment Trial two-sided Vasopressor website [DOI] 10.1186/s13063-020-04679-3 PMC 바로가기 [Article Type] Letter
Temporal and Location Variations, and Link Categories for the Dissemination of COVID-19–Related Information on Twitter During the SARS-CoV-2 Outbreak in Europe: Infoveillance StudyOriginal Paper Published on 2020-08-282022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] 2019 novel coronavirus addition Analysis analyzed applied Asia category center collected conducted Control Coverage COVID-19 COVID-19 outbreak COVID-19 pandemic database disease Disease surveillance dissemination early phase Europe European Future Guidance health informatics infodemic infodemiology information infoveillance location media Metadata Nature objective Occurrence pandemic platform prevalent prevention programming proportion Public public health Region resource resources Result SARS-CoV-2 significant increase social media social media platform Spread Temporal the disease the SARS-CoV-2 the SARS-CoV-2 virus the WHO Twitter Variation Volume was used WHO World Health Organization [DOI] 10.2196/19629 PMC 바로가기 [Article Type] Original Paper
Protocol for the process evaluation of the Promoting Activity, Independence and Stability in Early Dementia (PrAISED), following changes required by the COVID-19 pandemicSports and Exercise Medicine Published on 2020-08-272022-10-28 Journal: BMJ Open [Category] Coronavirus, Fulltext, MERS, [키워드] activity affected Analysis approval change contribute COVID-19 pandemic Dementia dissemination Ethics geriatric medicine Implementation study Independence Intervention Isolation mechanism pandemic Participants Promoting randomised controlled trial RCT rehabilitation rehabilitation medicine required Sports Medicine Support therapy Trial [DOI] 10.1136/bmjopen-2020-039305 PMC 바로가기 [Article Type] Sports and Exercise Medicine
High dose dexamethasone treatment for Acute Respiratory Distress Syndrome secondary to COVID-19: a structured summary of a study protocol for a randomised controlled trialCOVID-19에 따른 급성 호흡곤란 증후군에 대한 고용량 덱사메타손 치료: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-08-262022-08-13 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 active cancer acute respiratory distress acute respiratory distress syndrome Adult patients advance directives Advanced cancer age alpha error anticipated approved ARDS assessment assigned bilateral pulmonary infiltrates Blinding block breast-feeding Buenos Aires capture cardiac disease CEMIC clinical clinical trial code Complete concealed Confirmed COVID-19 COVID-19, Dexamethasone, Acute Respiratory Distress Syndrome, Randomised controlled trial, protocol, Steroids delirium develop Dexamethasone diagnosis of SARS-CoV-2 directive discharge disease dissemination do not resuscitate dose Effectiveness element End-Expiratory Pressure evaluate exclusion criteria Expiratory Pressure explained failure followed by Frequency glucocorticoid Glucocorticoids group hemodynamic High dose HIV infection hypoxemic Hypoxemic respiratory failure ICU Immunosuppression Immunosuppressive agents include inclusion criteria Infection Informed consent intensive care unit International legal guardian Length less Life expectancy local Ethics Committee mechanical ventilation Mortality multicenter muscle weakness Nosocomial infection Nosocomial infections number objective open open label open trial other disease other diseases outcome Palliative care PaO parallel group participant Participation Patient Patient care platform Pneumonia Positive end-expiratory pressure power power of 80% Prednisone pressure Prone position protocol R language random randomised randomised controlled trial randomization Randomized randomized clinical trial receive recruitment Registered renal renal disease respiratory respiratory distress Respiratory distress syndrome Respiratory failure resuscitate order RT-PCR Sample size SARS-COV-2 infection SARS-CoV-2 pneumonia secondary Secondary outcomes secondary to sequence Sequential Organ Failure Assessment severe immunosuppression SOFA Standard deviation status Stratified randomization Study protocol subject Support syndrome table terminal Terminal disease title Treatment treatment groups Trial Trial registration two-tailed alpha error Variation ventilator ventilator-free day Ventilator-free days ventilatory Version viral shedding weakness website women [DOI] 10.1186/s13063-020-04646-y PMC 바로가기 [Article Type] Letter
The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial인공호흡기를 사용하는 COVID-19 환자에서 위약과 비교하여 72시간 동안 1ng/kg/min 용량의 프로스타사이클린(일로프로스트) 주입 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-08-262022-08-13 Journal: Trials [Category] MERS, 임상, [키워드] (Iloprost (normal saline) 1:1 Acute coronary syndrome Adult patient Adult patients age anticipated Biomarker bleeding blinded Blinding block can not Capital Capital Region capture Clinicians comparator concealed conducted Confirmed Confirmed COVID-19 infection Consent coronary syndrome COVID-19 COVID-19 infection COVID-19 patients criteria Day defined Denmark dissemination dose element endothelial endotheliopathy EudraCT exclusion criteria exploratory facilitate FIVE heart failure Hvidovre Hospital hypersensitivity Iloprost intensive care unit intensive care units investigators Local mechanical ventilation mechanically ventilated mechanically ventilated COVID-19 patients mechanically ventilated patient multicenter normal saline number objective outcome parallel group participant Patient patients performed Placebo Pregnancy primary endpoint prostacyclin protocol randomisation randomised Randomized Randomized controlled trial recruitment REDCap Region Sample size sequence statisticians status stratified Study protocol Suspected thrombomodulin total sample size Trial Urine website Withdrawal [DOI] 10.1186/s13063-020-04696-2 PMC 바로가기 [Article Type] Letter
Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2현재 임상 시험 프로토콜 및 SARS-CoV-2에 대한 면역화를 위한 글로벌 노력Review Published on 2020-08-252022-09-10 Journal: Vaccines [Category] 비임상, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affecting Asia Brazil breath Candidates ChAdOx1 Characteristics clinical clinical trial clinical trials collaboration coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 current dissemination effective effort Health immunization inactivated Intervention Local MOST mRNA-based vaccine mRNA1273 outbreak platform Prevention strategy purified research and development (R&D) respiratory SARS-CoV-2 SARS-CoV-2 vaccine Scientific community selected severe acute respiratory syndrome Coronavirus systematic review treatment for COVID-19 United Arab Emirates United Kingdom USA Vaccine Vaccine development Viral Viral vector [DOI] 10.3390/vaccines8030474 PMC 바로가기 [Article Type] Review
Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trialsLetter Published on 2020-08-242022-10-29 Journal: Trials [Category] Coronavirus, MERS, [키워드] administration Analysis ARMS asked assessment Characteristics Chinese clinical trial Comparator group comparison Corticosteroid COVID-19 Critically ill patient defined Dexamethasone disease severity dissemination dose Effect element eligible EudraCT Evidence greater group heterogeneity High dose Hydrocortisone information Interaction Intervention intervention effect intervention group investigator ISRCTN less low dose meta-analyses Meta-analysis meta-regression Methylprednisolone Mortality Network meta-analysis objective Odds ratio Open-label outcome p-values participant Patient per day Placebo placebo-controlled primary analysis Prospective protocol provided quantified random-effect randomised controlled trial randomization Randomized Randomized controlled trials randomized trial Research Risk of bias RoB 2 secondary Serious Adverse Events Standard of care steroid Study protocol subgroup subgroups systematic review the WHO therapeutic dose therapy Treatment Trial trials usual care website WHO [DOI] 10.1186/s13063-020-04641-3 PMC 바로가기 [Article Type] Letter
Impact of Shenfu injection on a composite of organ dysfunction development in critically ill patients with coronavirus disease 2019 (COVID-19): A structured summary of a study protocol for a randomized controlled trialLetter Published on 2020-08-242022-10-29 Journal: Trials [Category] COVID-19, MERS, [키워드] 1:1 28-day mortality 48 hours adopted allergic allergy allocation concealment alveolar baseline bleeding blinded Blinding block randomization both group breastfeeding women caused China Chinese clinical clinical trial conducted control group coronavirus disease COVID-19 criteria Critical Critically ill patient death defined determine Diagnosis dissemination distribution element enrolled enrolment event exacerbated expected HIV hospital hospital cost ICU immunosuppressive drug Impact incidence include increase in injection intensive care Length lung malignant tumor management guideline multicenter National Health Commission number objective Obstructive Open-label organ organ dysfunction Organ failure outcome parallel group participant Patient patient recruitment patients patients with COVID-19 Pneumonia pregnant primary endpoint protocol provided pulmonary interstitial fibrosis random randomised randomised controlled trial randomization Randomized Randomized controlled trial Randomly receive recruit recruited researchers Sample size SAS sealed secondary endpoint Sepsis Seven severe malnutrition severity Shenfu injection shown SOFA SOFA score statistical status study group Study protocol supportive therapy the patient Total treat Treatment Two-arm underlying disease usual care vasoactive drug Volume website [DOI] 10.1186/s13063-020-04677-5 PMC 바로가기 [Article Type] Letter