Early events during human coronavirus OC43 entry to the cellArticle Published on 2018-05-082022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] Actin Affect Cell cellular receptor Cluster confocal microscopy Coronaviridae family determine entry routes event Features functional human coronavirus OC43 Infection infection process Molecular biology recognize Research RNA viruses specificity susceptible cell Vesicle virulence virus [DOI] 10.1038/s41598-018-25640-0 PMC 바로가기 [Article Type] Article
Genome-wide detection of conservative site-specific recombination in bacteria박테리아에서 보존적 부위 특이적 재조합의 게놈 전체 검출Research Article Published on 2018-04-052022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition adopted Altering Analysis appear applicability applied approach archaeal Bacteria Bacterial bacterial specy characterization classical Clostridium difficile components condition conserved contributing to dataset dependent on described detect DNA ecological niche ecological niches Effectiveness Epidemic expand expressed Features fluctuations fluorescent Frequency Gene Expression generate genomes genomic Genomic DNA growth heterogeneity identify in some in vitro inversion lack lineages mechanism nucleotide occur opens pathogen pathogenic bacteria phenotypic platform Population population level Prevalence proliferation provide Rapid Recombination referred to responsible robust Sequencing single-nucleotide stationary strain subpopulation survival thought undergo Variation [DOI] 10.1371/journal.pgen.1007332 PMC 바로가기 [Article Type] Research Article
Demographic and clinical profiles of Plasmodium falciparum and Plasmodium vivax patients at a tertiary care centre in southwestern India서남인도 3차 진료 센터에서의 말라리아 원충(P. falciparum 및 P. vivax) 환자의 인구통계학적 및 임상 프로필Research Published on 2016-11-252024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Characteristics diagnostics Epidemiology Features Goa MESA-ICEMR severity [DOI] 10.1186/s12936-016-1619-5 PMC 바로가기 [Article Type] Research
Potential Broad Spectrum Inhibitors of the Coronavirus 3CL pro : A Virtual Screening and Structure-Based Drug Design StudyArticle Published on 2015-12-152022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] 3CL pro 3CLpro acute respiratory syndrome Antiviral approach can be used Cluster Compound Consensus coronavirus cross defined disease drug drug design drug target experiments Features Glide highlight Human human coronaviruses Infection inhibitor less likelihood MERS Middle East molecular molecular docking molecular dynamics outbreak Potential provide screened Screening sequence homology significantly Spectrum Structure-based drug design subset syndrome these compound Virtual screening [DOI] 10.3390/v7122963 PMC 바로가기 [Article Type] Article
A structural view of coronavirus–receptor interactionsArticle Published on 2014-10-142022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] antibody antigenic binding Cell cell entry circulation complex structure complex structures coronavirus CoV crystal structure determinant Ectoenzymes Evolution facilitate Features glycoprotein Glycoproteins highlight host cell host cells hosts infections Interaction membrane multifunctional neutralization neutralize outbreak Particle penetrate penetration platform RBD receptor Receptor-binding domain receptors recognize reported responsible specificity surface receptor Transmission virus virus entry Virus neutralization Virus–receptor [DOI] 10.1016/j.virusres.2014.10.005 PMC 바로가기 [Article Type] Article
Molecular mechanisms of severe acute respiratory syndrome (SARS)Review Published on 2005-01-202022-10-28 Journal: Respiratory Research [Category] Coronavirus, [키워드] acute respiratory syndrome approach caused contribute coronavirus Deleterious Effect effort Epidemics Features Genome Health immune immune system indirect effect infections Infectious disease Interaction Laboratory mechanism molecular mechanisms morbidity and mortality mutability Novel coronavirus Occurrence offer Open reading frame outbreak Pathogenesis Prevent pulmonary pathological Region required Research Respiratory disease SARS SARS-CoV severe Severe acute respiratory syndrome target cell the disease therapy vaccination Vaccine viral genome virulence virus widespread [DOI] 10.1186/1465-9921-6-8 PMC 바로가기 [Article Type] Review
Coronaviridae and SARS-associated Coronavirus Strain HSR1Research Published on 2004-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 addition affected Analysis biologic Cell cell membrane Characteristics Coronaviridae coronavirus CoV determined Evidence Features form full-length generate Genetic genomic hotel Infected Infection inhibited Isolation Italian Italy molecular New coronavirus outbreak Patient Plaque assay Real-time PCR required SARS-coronavirus SARS-CoV sequence specimen sputum strain TaqMan the patient Vero Cell Vesicle viral genome viral genome sequence virion [DOI] 10.3201/eid1003.030683 PMC 바로가기 [Article Type] Research