A Machine Learning Explanation of the Pathogen-Immune Relationship of SARS-CoV-2 (COVID-19), and a Model to Predict Immunity and Therapeutic Opportunity: A Comparative Effectiveness Research StudyOriginal Paper Published on 2020-10-192022-10-29 Journal: Jmirx Med [Category] COVID-19, [키워드] 95% CI Accuracy age Algorithm association Asymptomatic asymptomatic patient AUROC build carrier Cell characteristic China Chinese Clinical data Comorbidities Comparative Contact COVID-19 COVID-19 immunity COVID-19 symptom diagnosed differentiator District Effectiveness excluded explanation extreme Factor female growth hospital identify immune immune factor immune factors Immunity immunological individual infect infected with COVID-19 Infectious disease M-CSF machine machine learning machine learning analysis Macrophage male mass vaccinations median age Model objective observation Outbreaks outcome Patient patients patients with COVID-19 point of care positive predict predicted primary care Primary outcome programming public health relationship Research Result RT-PCR SARS-CoV-2 SCGF-β selected Sex single-center statistical statistically significant stem-cell growth factor-beta Symptom symptomatic symptomatic case Testing Therapeutics therapy Treatment treatment for COVID-19 understanding Vaccine were measured were recorded with COVID-19 [DOI] 10.2196/23582 PMC 바로가기 [Article Type] Original Paper
Modelling COVID 19 in the Basque Country from introduction to control measure responseArticle Published on 2020-10-142022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] adjusted Analysis approaches assist Asymptomatic calculated Computational biology and bioinformatics country Course COVID 19 COVID-19 develop disease transmission Diseases effective effort epidemiological data flexible force growth growth rate Health health manager Hospital admissions Hospitalized implication information lifted lockdown measure Measures Mild MONITOR National partial lockdown positive predict responses Severe infection shown statistical Systems biology tested the epidemic [DOI] 10.1038/s41598-020-74386-1 PMC 바로가기 [Article Type] Article
A Countrywide Survey in Saudi Arabia Regarding the Knowledge and Attitude of Health Care Professionals about Coronavirus Disease (COVID-19)Article Published on 2020-10-122022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] 2019-nCoV adjusted odds ratio analyzed Attitude Care conducted coronavirus prevention COVID-19 cross-sectional diploma disease domain FIVE geographical region groups hcp Health health care professionals help higher risk independent variable infection control information Kingdom knowledge Ministry of Health multivariate logistic regression nomenclature Odds ratio pandemic percentages positive attitude Preparedness planning professional Qualtrics question questionnaire Region SARS-CoV2 Saudi Arabia SPSS statistical survey variable was performed website [DOI] 10.3390/ijerph17207415 PMC 바로가기 [Article Type] Article
FUSI-CAD: Coronavirus (COVID-19) diagnosis based on the fusion of CNNs and handcrafted featuresArtificial Intelligence Published on 2020-10-122022-10-29 Journal: PeerJ Computer Science [Category] COVID-19, [키워드] Accuracy addition Analysis CAD can be used CNN co-occurrence Computed tomography computer-aided diagnosis (CAD) conditions Convolution neural networks (CNN) coronavirus Coronavirus (COVID-19) COVID-19 COVID-19 diagnosis CT-scan dataset Diagnosis diagnostic diagnostics Discrete wavelet transform (DWT) faster fatigue feature Grey level co-occurrence matrix (GLCM) help Laboratory tests Non-COVID-19 Odds ratio pandemic virus Patient Precision Prevent primary stage provide radiologist reduce SARS-CoV-2 sensitivity specificity Spread statistical the disease [DOI] 10.7717/peerj-cs.306 PMC 바로가기 [Article Type] Artificial Intelligence
COVID-19 prevalence estimation: Four most affected African countriesSpecial issue on Modelling and Forecasting the 2019 Novel Coronavirus (2019-nCoV) Transmission Published on 2020-10-122022-10-30 Journal: Infectious Disease Modelling [Category] COVID-19, [키워드] adopted affected African Analysis applied ARIMA ARIMA models average China coronavirus country COVID-19 criterion dataset death different disease disease effective examined exponential growth Forecasting GMT Government growth Health authority information Linear regression model management MONITOR Nigeria outbreak pandemic parameter Precaution predict Prevalence prevalence of COVID-19 public health reported selected statistical Statistical tools statistically significant time series model virus website World Health Organization Wuhan [DOI] 10.1016/j.idm.2020.10.002 PMC 바로가기 [Article Type] Special issue on Modelling and Forecasting the 2019 Novel Coronavirus (2019-nCoV) Transmission
Estimation of the basic reproduction number (R0) for the novel coronavirus disease in Sri LankaResearch Published on 2020-10-072022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, SARS, [키워드] basic reproduction number Bayesian calculate calculated caused compartmental model coronavirus COVID-19 determine disease estimation growth implication infected individual likelihood measure novel coronavirus disease objective parameters R0 ranged reduced Reproduction number Result Spread statistical the disease Transmissibility unit Variation was obtained was used [DOI] 10.1186/s12985-020-01411-0 PMC 바로가기 [Article Type] Research
Dynamic Panel Surveillance of COVID-19 Transmission in the United States to Inform Health Policy: Observational Statistical StudyOriginal Paper Published on 2020-10-052022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] Administered Analysis applied approach cause census changes in Combination Contagion Contamination COVID-19 COVID-19 cases COVID-19 transmission declines deficiency dependent on driven by dynamic estimate Evolution generate Government Health policy increase in Infection Intensive Measurement error Metrics models National objective occur operationalization pandemic Panel parameter persistence Positive test provide public health Region remained reopening reopening America required Result Safe SARS-CoV-2 SARS-CoV-2 infections significantly increased Spread Static statistical statistical model subject Surveillance sustained Test the United State Transmission Transmission model United State Validity variety virus [DOI] 10.2196/21955 PMC 바로가기 [Article Type] Original Paper
Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trialsResearch article Published on 2020-10-012022-10-05 Journal: Medical Hypotheses [Category] 임상, 진단, 치료법, [키워드] activate acute respiratory distress syndrome Alpha alveolar Anti-inflammatory therapy Anti-viral anti-viral effect anticoagulant therapy anticoagulation approach ARDS ARDSacute respiratory distress syndrome Bacterial Beta Blood C-reactive protein Care Cell chemokines clinical outcomes clinically Coagulopathy Comorbidities Computerized tomography concerning Coronaviruses COVID-19 COVID-19 infection CoVscoronaviruses criteria CRPC-reactive protein CTcomputerized tomography CXCL10chemokines CXCL9 cytokine D-dimer diagnose Diagnosis diagnostic DICdisseminated intravascular coagulation Digital Disseminated intravascular coagulation distress effective elevated emboli extreme General population GGOground glass opacities gluthathione ground glass opacities GSHgluthathione Health Health authority healthy help high mortality rate highest hypothetical ICUIntensive Care Unit identify IL-10interleukin 10 IL-12interleukin 12 IL-18interleukin 18 IL-1βinterleukin 1 beta IL-33interleukin 33 IL-6interleukin 6 IL-7Interleukin 7 IL-8interleukin 8 immune immune function immunomodulatory implementation increase in individual individuals Inflammation intensive care unit interleukin 1 beta Interleukin 10 interleukin 12 interleukin 18 interleukin 33 interleukin 6 Interleukin 7 interleukin 8 Intervention Isolation Ivermectin lactic dehydrogenase LDHlactic dehydrogenase LDLyme disease literature review Lyme disease macrophage activation syndrome MASmacrophage activation syndrome MERS coronavirus MERS-CovMERS coronavirus morbidity and mortality Multiorgan dysfunction N-acetyl-cysteine NACN-acetyl-cysteine NCPnovel coronavirus pneumonia New NF-κB novel coronavirus pneumonia NSnutritional support nutraceutical nutritional support organ outcomes oxygen Oxygenation pandemic Pathways Patient performed physical distancing Pneumonia precursor Prevent protocol questionnaire Randomized controlled trial randomized trial randomized, controlled trials required resource respiratory therapy resulting risk SARS-CoV-2severe acute respiratory syndrome coronavirus 2 scored screening questionnaire second Sepsis serum severe acute respiratory syndrome coronavirus 2 severe complication silent statistical statistically Stress sulforaphane Support Symptom symptomatic infection TGFβtransforming growth factor beta the disease therapy thrombotic event TNF-αtumor necrosis factor alpha transforming growth factor beta Transmission Treatment Treatment strategies tumor necrosis factor alpha ventilator vital sign Vitamin C WHOWorld Health Organization with COVID-19 World Health Organization [DOI] 10.1016/j.mehy.2020.109851 [Article Type] Research article
Analysis on the current quality standards of Chinese materia Medica used in COVID-19 prevention and treatmentResearch article Published on 2020-10-012022-10-05 Journal: Pharmacological research [Category] 치료법, [키워드] Characteristics China Chinese Chinese Materia Medica CMM collected compounds Consensus Coronavirus disease 2019 COVID-19 Evidence Frequency highest International ISO/TC 249 marker Medicine pandemic Patent promote Quality control Quality standards Result selected statistical TCM Traditional Chinese medicine Treatment variety [DOI] 10.1016/j.phrs.2020.105074 [Article Type] Research article
Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of OutcomeACE2 변이의 스펙트럼 분석은 COVID-19에 대한 감수성과 결과의 심각성에 대한 희귀 및 공통 변이의 가능한 영향을 시사합니다Genetics Published on 2020-09-292022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 variant ACE2 variants acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect allele frequency alternative allele analyzed angiotensin angiotensin-converting enzyme-2 caused Cohort common coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 dataset disease severity eQTL European population European populations explain frequencies Frequency Genetic variant genetic variants Genome Aggregation Database gnomAD gnomAD database Health Organization influence Missense missense variant mutations objective outcome pandemic Patient patients with COVID-19 Regulatory respiratory Respiratory disease Result rs146598386 rs73195521 rs755766792 Russia Russian population severity Severity of disease Southern European population Spectrum statistical Support susceptibility variant variants whole-exome sequencing World Health Organization [DOI] 10.3389/fgene.2020.551220 PMC 바로가기 [Article Type] Genetics