Evolutionary Relationships between Bat Coronaviruses and Their HostsResearch Published on 2007-10-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome analysis association bat bats biologic caused coronavirus Coronaviruses CoV CoVs Evolution evolutionary relationship examined Host host shifts Human implication occurred outbreak Phylogeny phylogeography recent related related viruses relationship Research Respiratory illness RNA-dependent RNA polymerase SARS SARS-CoV sequence shifting suggested trait traits virus virus [DOI] 10.3201/eid1310.070448 PMC 바로가기 [Article Type] Research
The association of RANTES polymorphism with severe acute respiratory syndrome in Hong Kong and Beijing ChineseResearch Article Published on 2007-06-012022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, MERS, [키워드] acute respiratory syndrome Admission Affect antiviral action association Beijing Chinese controls death examined G allele Genotype Hong Kong increased risk individual Inflammation intensive care unit IP-10 outcome Pathogenesis polymorphism RANTES Replication Result risk of death SARS patient susceptibility tested [DOI] 10.1186/1471-2334-7-50 PMC 바로가기 [Article Type] Research Article
Genetic variability of human coronavirus OC43‐, 229E‐, and NL63‐like strains and their association with lower respiratory tract infections of hospitalized infants and immunocompromised patientsResearch Article Published on 2006-05-232022-11-01 Journal: Journal of medical virology [Category] Coronavirus, [키워드] Acute respiratory infection addition Adult age association Bronchiolitis caused cell line children Coinfection coronavirus CoV detect detected diagnosed Diagnosis different distribution found Gene HCoV hospital Hospitalized human coronavirus infections Immunocompromised Immunocompromised patient Immunocompromised patients immunological Inc Infant Infection involved Isolation Lower Lower respiratory tract molecular monoclonal antibodies not found other respiratory virus pathology Patient patients phylogenetics Pneumonia primer primer pair primer set reached Respiratory tract infections RT‐PCR RT‐PCR screened severe respiratory syndrome strain Strains susceptible targeting gene upper respiratory tract Variability were infected [DOI] 10.1002/jmv.20645 PMC 바로가기 [Article Type] Research Article
Time Course and Cellular Localization of SARS-CoV Nucleoprotein and RNA in Lungs from Fatal Cases of SARSResearch Article Published on 2006-02-032022-10-29 Journal: PLoS Medicine [Category] Coronavirus, MERS, [키워드] 2003 acute respiratory syndrome alveolar alveolar epithelium antiviral therapy appear assay association Autopsy Canada case cellular China Clinical course clinical disease collected compared coronavirus detected died disease etiological Evidence finding Hong Kong humans illness onset immunohistochemistry In situ Infected involved knowledge less Localization lung lung tissue Lungs Macrophage macrophages monoclonal antibody nucleoprotein outbreak Pathogenesis Patient patients with SARS pneumocyte Pulmonary pathology Region Replication RNA SARS Coronavirus SARS-CoV Seven symptom onset target the disease time Toronto Treatment viral infection virus widespread [DOI] 10.1371/journal.pmed.0030027 PMC 바로가기 [Article Type] Research Article
Croup Is Associated with the Novel Coronavirus NL63Research Article Published on 2005-08-232022-10-29 Journal: PLoS Medicine [Category] Coronavirus, [키워드] absence age analysed association children Co-infection collected compared coronavirus Croup detected determined different disease finding fraction Germany HCoV-NL63 hospitalised patient Infection investigated Lower respiratory tract median nasopharyngeal secretion NL63 novel occur Outpatient parainfluenza virus 3 Patient positive prevalent Quantitative Real-time PCR Region respiratory syncytial virus respiratory virus respiratory viruses RNA Sample significantly higher suffered Viral load Viral RNA [DOI] 10.1371/journal.pmed.0020240 PMC 바로가기 [Article Type] Research Article
Monoclonal antibodies versus reverse transcription‐PCR for detection of respiratory viruses in a patient population with respiratory tract infections admitted to hospitalResearch Article Published on 2004-12-152022-11-01 Journal: Journal of medical virology [Category] Coronavirus, [키워드] added addition Adults another respiratory virus antibody approach assays association Bronchoalveolar lavage bronchoalveolar lavage sample caused circulating Coinfection Combination coronavirus detected Diagnosis diagnostic examined group H1N1 H3N2 HCoV hospital Human coronavirus human metapneumovirus human parainfluenza virus Human respiratory syncytial virus immunological Inc infected children infecting Infection infections influenza virus investigated less Lower respiratory tract lung transplant majority métapneumovirus molecular Molecular assay monoclonal antibody nasopharyngeal Patient patient population patients peaked pediatric positive proportion recipients respiratory coinfections respiratory infections respiratory syncytial virus respiratory tract infection respiratory viral respiratory virus respiratory virus reverse transcription RT‐PCR RT‐PCR searched Strains tested virus virus were infected [DOI] 10.1002/jmv.20276 PMC 바로가기 [Article Type] Research Article