Standard Care Versus Awake Prone Position in Adult Nonintubated Patients With Acute Hypoxemic Respiratory Failure Secondary to COVID-19 Infection—A Multicenter Feasibility Randomized Controlled TrialCOVID-19 감염에 따른 급성 저산소성 호흡부전이 있는 성인 삽관되지 않은 성인 환자의 깨어 있는 자세와 깨어 있는 자세 비교 - 다기관 타당성 무작위 대조 시험Randomized Controlled Trial Published on 2021-05-052022-08-13 Journal: Journal of Intensive Care Medicine [Category] MERS, 임상, [키워드] 6 hour 6 hours acute hypoxic respiratory failure acute respiratory distress acute respiratory distress syndrome adverse events Awake prone positioning clinical trial conditions conducted Controlled COVID-19 COVID-19 pneumonia exceeded failure feasibility Feasibility study feasible group help hypoxia hypoxic respiratory failure knowledge maintain no significant difference non-intubated patient non-intubated patients observational studies observational study outcome oxygen pandemic parallel group Patient Pneumonia position Primary outcome prone prone group Prone position prone positioning proportion protocol Randomized rationale recruited requiring supplemental oxygen respiratory respiratory distress Respiratory failure Result Safe saturation secondary outcome Secondary outcomes secondary to significant difference Standard standard care supine supine group supplemental oxygen syndrome Trial with COVID-19 [DOI] 10.1177/08850666211014480 PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 Pandemic and Physical Exercise: Lessons Learnt for Confined CommunitiesPsychology Published on 2021-05-052022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] addition affected approach Asylum characterized complex coronavirus country COVID-19 COVID-19 outbreak COVID-19 pandemic death deleterious effect Effect exercise General population global public health group Health Health status healthcare high risk immune system Immunotherapy Impact impacted IMPROVE incarcerated Isolation lack lesson lockdown maintain mental health mitigate outcome pandemic physical physical activity Population prison recommendation reduce reduced respiratory SARS-CoV-2 sedentary social distancing Specific [DOI] 10.3389/fpsyg.2021.618585 PMC 바로가기 [Article Type] Psychology
Building learning organizational culture during COVID-19 outbreak: a national studyResearch Article Published on 2021-05-042022-10-28 Journal: BMC health services research [Category] Coronavirus, SARS, [키워드] adaptive basic building collected component connection country COVID-19 COVID-19 crisis COVID-19 outbreak cross-sectional Culture Descriptive analysis dimension effective extrinsic Factor Health Health Organization healthcare Healthcare professional Healthcare system hospital identify inquiry intrinsic Knowledge‐share learning Learning organization lowest maintain Multiple linear regression Multiple regression National organization organizations Pandemics predict predicted R 2 Result Saudi Arabia significantly staff statistically variable variables Variation was performed [DOI] 10.1186/s12913-021-06454-9 PMC 바로가기 [Article Type] Research Article
A complementary critical appraisal on systematic reviews regarding the most efficient therapeutic strategies for the current COVID-19 (SARS-CoV-2) pandemic현재 COVID-19(SARS-CoV-2) 전염병에 대한 가장 효율적인 치료 전략에 관한 체계적인 검토에 대한 보완적인 비판적 평가Meta-Analysis Published on 2021-05-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료제, [키워드] Administered article Chloroquine clinical symptom Clinical symptoms clinical trial clinical trials complementary concept coronavirus COVID-19 COVID-19 drug treatment COVID-19 pandemic COVID-19 treatment criteria critical appraisal database death Deleterious drug drug treatment Effect Efficacy Evidence Favipiravir Hydroxychloroquine Hypotension Immunoglobulin immunoglobulins Increasing initial initial screening Liver function test Lopinavir Lopinavir/ritonavir maintain mechanical ventilation Medicine mesh terms meta-analyses mortality rate pandemic Patient plasma reduced Remdesivir Research resources Ritonavir SARS-CoV-2 Science Direct searched severe symptoms severely ill patients Side effect Side effects steroid Steroids subsequent suggested systematic review systematic reviews the cytokine storm therapeutic strategy Tocilizumab Treatment viral clearance were assessed [DOI] 10.1002/jmv.26811 PMC 바로가기 [Article Type] Meta-Analysis
Apheresis physician well-being during the COVID-19 pandemic: Results of a surveyClinical Trial Published on 2021-05-012022-10-05 Journal: Transfusion [Category] SARS, 임상, [키워드] Affect Analysis ANOVA apheresis attending physicians Burnout changes in chi-square tests conducted COVID-19 COVID-19 pandemic determine enzymatic nanomotors Frequency IMPROVE institution maintain measure pandemic performed Personal protective equipment physician provided public health crisis question reported representing resolved resource resources response Result SARS-CoV-2 Society Stressor t-test the United State variables widespread [DOI] 10.1111/trf.16340 PMC 바로가기 [Article Type] Clinical Trial
Cytokine Profiles Before and After Immune Modulation in Hospitalized Patients with COVID-19COVID-19로 입원한 환자의 면역 조절 전후 사이토카인 프로필Article Published on 2021-05-012022-09-11 Journal: Journal of Clinical Immunology [Category] SARS, 바이오마커, 진단, [키워드] administration Admission Adult patients Algorithm association Care cluster analysis combination therapy COVID-19 Critical Critical disease CRP level CRP levels cytokine cytokine panel cytokine profile cytokine release Cytokine release syndrome Cytokines D-dimer disease severity dysregulation elevated Elevation elevations glucocorticoid Glucocorticoids HFNC Hospital stay hospitalized patient hospitalized patients Hyperinflammatory IFN-γ IL-10 IL-6 IL-6 inhibition IL-6 level immune immune dysregulation incidence increase in interleukin interleukin-10 interleukin-2 receptor (soluble) large cohort maintain marker moderate modulate modulating Mortality nippv oxygen Oxygen requirement pathway Patient performed Potential biomarker potential biomarkers profile receive receiving receptor response to treatment retrospective SARS-CoV-2 SARS-COV-2 infection severity significantly increased SpO2 Therapies therapy Tocilizumab treated Treatment with COVID-19 [DOI] 10.1007/s10875-020-00949-6 PMC 바로가기 [Article Type] Article
Effectively Conducting Oncology Clinical Trials During the COVID-19 PandemicShort communication Published on 2021-05-012022-10-05 Journal: Advances in Radiation Oncology [Category] 임상, [키워드] adaptive approach Cancer clinical clinical trial Conducting coronavirus disease COVID-19 COVID-19 pandemic Critical Decline declined Enrollment help initial maintain material Multicenter trial oncology pandemic Patient pulmonary toxicity Radiation ranged Research Result risk Therapeutic benefit Trial [DOI] 10.1016/j.adro.2021.100676 [Article Type] Short communication
Impact of COVID-19 pandemic on functioning of cytopathology laboratory: Experience and perspective from an academic centre in New YorkCOVID-19 대유행이 세포병리학 실험실 기능에 미치는 영향: 뉴욕에 있는 학술 센터의 경험과 관점Article Published on 2021-05-012022-09-11 Journal: Cytopathology : official journal of the British So [Category] SARS, 치료기술, [키워드] Care Contagion COVID-19 COVID-19 pandemic COVID-19 patients cytopathology expected experience Health Health care healthcare Healthcare workers hospital Impact impacted Infection Laboratory maintain Medical care medical service mitigate New York operation pandemic Patient care Personal protective equipment Perspective reduce resources Spread USA Workplace workplace safety [DOI] 10.1111/cyt.12953 PMC 바로가기 [Article Type] Article
Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infectionSARS-CoV-2 감염에 대한 신경모세포종 및 교모세포종 세포주의 감수성Article Published on 2021-05-012022-09-11 Journal: Brain research [Category] SARS, 치료기술, [키워드] Analysis Apoptosis Cell cell line cell lines cell type cells Coronavirus-2 CTSB CTSL Cytopathic effect death demonstrated described downregulation epithelial cell epithelial cells Express Gene Expression Genes Glioblastoma Glutamate idea In situ hybridization infected cell infected cells Infection maintain MOI MOIs Neuroblastoma neuronal neurotropism Perspective quantification replicate retinoic acid RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 SH-SY5Y susceptibility tropism upregulation Vero E6 VERO E6 cells virus were expressed were infected [DOI] 10.1016/j.brainres.2021.147344 PMC 바로가기 [Article Type] Article
Sustained coronavirus disease 2019-related organizing pneumonia successfully treated with corticosteroid코르티코스테로이드로 성공적으로 치료된 지속적인 코로나바이러스 질병 2019 관련 조직성 폐렴Case Reports Published on 2021-05-012022-09-11 Journal: Respiratory investigation [Category] MERS, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration alleviation alveolar biopsy Case report coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 COVID-19 pneumonia Cryobiopsy dysfunction epithelial feature Infection Injury Japanese lung maintain Organizing pneumonia oxygen oxygen saturation Patient Pneumonia Prednisolone required respiratory Respiratory failure Respiratory function respiratory symptom respiratory symptoms SARS-CoV-2 severe acute respiratory syndrome Coronavirus steroid steroid treatment Symptoms treat treated use of corticosteroid [DOI] 10.1016/j.resinv.2020.12.005 PMC 바로가기 [Article Type] Case Reports