Milestones in Personalized Medicine: From the Ancient Time to Nowadays—the Provocation of COVID-19Genetics Published on 2020-11-302022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] Clinical practice COVID-19 COVID-19 pandemic COVID−19 Diagnosis diagnostic effective Evidence Genetic genetic background healthcare highlight individual Inflammation limitation malaria milestone over Personalized medicine pharmacogenomics problem public health raising regimen starting therapeutic Therapeutic approach therapy time Treatment [DOI] 10.3389/fgene.2020.569175 PMC 바로가기 [Article Type] Genetics
The COVID-19 pandemic and impact on breast cancer diagnoses: what happened in England in the first half of 2020Brief Communication Published on 2020-11-302022-10-04 Journal: British Journal of Cancer [Category] MERS, 신약개발, [키워드] analysed Breast cancer cancer diagnosis collected COVID-19 pandemic Delay diagnosed Diagnosis England explained measure NHS outcomes Outcomes research Patient proportion time Treatment widespread [DOI] 10.1038/s41416-020-01182-z PMC 바로가기 [Article Type] Brief Communication
Vitamin D Insufficiency May Account for Almost Nine of Ten COVID-19 Deaths: Time to Act. Comment on: “Vitamin D Deficiency and Outcome of COVID-19 Patients”. Nutrients 2020, 12 , 2757Comment Published on 2020-11-272022-10-31 Journal: Nutrients [Category] Coronavirus, SARS, [키워드] Act Comment COVID-19 insufficiency nutrient time Vitamin D [DOI] 10.3390/nu12123642 PMC 바로가기 [Article Type] Comment
Reply to: “Vitamin D Insufficiency May Account for Almost Nine of Ten COVID-19 Deaths: Time to Act. Comment on: Vitamin D Deficiency and Outcome of COVID-19 Patients. Nutrients 2020, 12 , 2757”Reply Published on 2020-11-272022-10-31 Journal: Nutrients [Category] Coronavirus, SARS, [키워드] Act Comment COVID-19 insufficiency nutrient Reply time Vitamin D [DOI] 10.3390/nu12123643 PMC 바로가기 [Article Type] Reply
Treatment of COVID‐19 patients with the anti‐CD6 antibody itolizumabOriginal Article Published on 2020-11-252022-10-31 Journal: Clinical & Translational Immunology [Category] COVID-19, [키워드] administration adverse event age antibody Autoimmune disease Biomarker cascade CD6 Clinical data Combination Comorbidities Concentration COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Critical Cytokine release syndrome death Deterioration discharged events expressed FiO2 glycoprotein hospitals Hyperinflammatory hyperinflammatory state ICU IL‐6 individual itolizumab lethality rate Lower Lung function moderate monoclonal antibody morbidity and mortality Mortality Most patient multiple cytokine National neurological manifestation NLR objective pathway Patient patients Prevent prevented proportion protocol reduce reduced Result SARS‐CoV‐2 SARS‐COV2 Secondary objective severe cases Severe patient severe patients significantly subject T lymphocyte T‐cell activation Th1/Th17 therapy time treated Treatment Ventilation [DOI] 10.1002/cti2.1218 PMC 바로가기 [Article Type] Original Article
Effect of an Aerosol Box on Intubation in Simulated Emergency Department Airways: A Randomized Crossover StudyRandomized Controlled Trial Published on 2020-11-242022-10-04 Journal: Western Journal of Emergency Medicine [Category] SARS, 임상, [키워드] acute respiratory syndrome aerosol Aerosol box airway Box coronavirus crossover Department distribution Effect Emergency Endotracheal intubation Evidence FIVE glottic Impact increase intubate intubation intubations no significant difference number of attempt outcome pandemic participant patients performed Primary outcome Protective randomization Randomized Result secondary sequence significantly significantly more time variety [DOI] 10.5811/westjem.2020.8.48901 PMC 바로가기 [Article Type] Randomized Controlled Trial
Whites’ County-Level Racial Bias, COVID-19 Rates, and Racial Inequities in the United StatesArticle Published on 2020-11-232022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, [키워드] adjusted association average bias black center coronavirus disease COVID-19 COVID-19 incidence COVID-19 mortality cumulative Evidence explicit greater Health health inequities incidence incidence rate incidence rates Intervention Johns Hopkin Linear regression mortality rate Mounting New York outcome outcomes overall mortality predict predicted Racial racism and discrimination reveal social determinants of health Standard deviation the United State time white with COVID-19 [DOI] 10.3390/ijerph17228695 PMC 바로가기 [Article Type] Article
COVID-19 Pandemic: Time to Revive the Cyclophilin Inhibitor AlisporivirCOVID-19 팬데믹: Cyclophilin 억제제 Alisporivir를 되살릴 시간Article Published on 2020-11-192022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 비임상, 임상, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus alisporivir Antiviral breath caused clinical development clinical endpoint coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus infection Coronaviruses COVID-19 cyclophilin cyclophilin. cyclosporine cyclosporine A Epidemic form include Infection life cycle Middle East Middle East respiratory syndrome Coronavirus Patient Phase 3 Pneumonia preclinical data reached respiratory respiratory syndrome coronavirus risk SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severity tested therapeutic option time treat Treatment treatment of COVID-19 Virological [DOI] 10.1093/cid/ciaa587 PMC 바로가기 [Article Type] Article
COVID-19: The First 30 Days at a UK Level 1 Trauma Centre and Lessons LearntOrthopedics Published on 2020-11-182022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Admission Admissions age approval Autoimmune disease average baseline biochemical Biomarker blood tests Cancer Care cause change Chest chest X-ray clinical symptom collected Comorbidities complex Computed tomography contracting the virus COVID COVID-19 CXR Day demographics diabete died effective eight Escalation group Hospital epidemiology Immunosuppressive medication IMPROVE incidence Increased Injury Intensive Isolation lesson Lessons learnt level 1 lockdown majority males management mechanism medication Mortality Older orthopedics and trauma outcome Patient patients performed positive positive patients problem radiological reduced reducing remote required respiratory symptom Result second wave Sex significantly study period survived Swab Swab test Symptom tested the disease time trauma virus Volume was increased [DOI] 10.7759/cureus.11547 PMC 바로가기 [Article Type] Orthopedics
COVID-SGIS: A Smart Tool for Dynamic Monitoring and Temporal Forecasting of Covid-19Public Health Published on 2020-11-172022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, [키워드] 95% CI addition ARIMA Brazil country Course COVID-19 forecasting cumulative current spread database death deaths dynamic dynamic forecasting systems evaluate Forecasting health-care service include Infectious diseases information intelligent forecasting systems Intervention limits monitoring National new coronavirus SARS-CoV-2 notification pandemic problems public health reported Rio Grande robust SARS-CoV-2 spread forecast SmaRT South America statistical significance statistically significant Surveillance System Temporal the disease time [DOI] 10.3389/fpubh.2020.580815 PMC 바로가기 [Article Type] Public Health