Transformation of primary care during the COVID-19 pandemic: experiences of healthcare professionals in eight European countriesResearch Published on 2021-08-072022-10-28 Journal: The British Journal of General Practice [Category] COVID-19, MERS, SARS, [키워드] adjust analysed Belgium Care Combination conducted COVID-19 COVID-19 pandemic Critical deductive thematic analysis eight England European European country exploratory facilitate Germany Greece Guidance Healthcare professional information interview Ireland Local mental health Netherlands Non-COVID-19 Patient care Poland Practical training preservation primary care Primary Health Care professional qualitative research qualitative study representation Result secondary care Semi-structured interviews Support transcribed transformation [DOI] 10.3399/BJGP.2020.1112 PMC 바로가기 [Article Type] Research
COVID-19 Vaccination in Lower-Middle Income Countries: National Stakeholder Views on Challenges, Barriers, and Potential SolutionsPublic Health Published on 2021-08-062022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, [키워드] access analysed approach approval authority childhood Community conducted country COVAX COVID-19 COVID-19 vaccination COVID-19 vaccine dose drug eight expand facility framework global pandemic Government Health immunisation income Local MOST overcome pandemic Population populations Potential potential barrier progressed solution stakeholder perspective Structure suggested the vaccine vaccinate vaccination Vaccine vaccine delivery Vaccine hesitancy vaccine provider challenges Vaccines View Volunteer [DOI] 10.3389/fpubh.2021.709127 PMC 바로가기 [Article Type] Public Health
The Impact of SARS-CoV-2 (COVID-19) Pandemic on International Dermatology Conferences in 2020Medicine Published on 2021-08-052022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] analyzed changes conducted Conference congress coronavirus COVID-19 COVID-19 pandemic Dermatology eight facilitated FIVE Human Impact International investigated involved knowledge limit MOST nine outbreak Pandemics platform SARS-CoV-2 significantly Spread the SARS-CoV-2 Travel Virtual website [DOI] 10.3389/fmed.2021.726037 PMC 바로가기 [Article Type] Medicine
SARS-CoV-2 host cell entry: an in silico investigation of potential inhibitory roles of terpenoidsResearch Published on 2021-08-052022-10-30 Journal: Journal of Genetic Engineering & Biotechnology [Category] COVID-19, [키워드] Abietane diterpenes: Molecular docking ACE2 ACE2 binding African binding binding free energy catalytic Clustering analysis COVID-19 pandemic docked docking drug drug-likeness eight Entry inhibitor first stage hotspot human Angiotensin-converting enzyme in silico in vitro in vivo inhibiting inhibitory Interaction interactions MD simulation MERS-CoV molecular molecular docking analysis pentacyclic performed plant preserved protease Protein protein targets Proteins provide residue Result S2 subunit SARS-CoV SARS-CoV-2 SARS-CoV-2 host cell SARS-COV-2 infection SARS-CoV-2 spike protein screened serine 2 Spike protein stability supplementary material targeting targets terpenoids the RBD the SARS-CoV-2 therapeutic strategy TMPRSS2 trajectory transmembrane viral cell [DOI] 10.1186/s43141-021-00209-z PMC 바로가기 [Article Type] Research
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopesArticle Published on 2021-08-032022-10-04 Journal: Nature Communications [Category] MERS, SARS, 변종, [키워드] ACE2-binding site acute respiratory syndrome Analysis antibodies Antiviral bind binding binding epitope circulating variant circulating variants class comparison conserved coronavirus COVID-19 therapeutics cryo-EM structures Cryoelectron microscopy determine disrupt effective eight epitope host receptor inaccessible indicate mechanisms Microbiology Microscopy nanobody neutralization neutralize Neutralizing Neutralizing activity neutralizing antibody neutralizing epitope potent provided RBD Receptor binding domain recognize reveal SARS-CoV SARS-CoV-2 SARS-CoV-2 spike Spike protein STABLE structural biology Structure target the SARS-CoV-2 unique Vaccine variant variants of concern variety virus VoC VOCs [DOI] 10.1038/s41467-021-24963-3 PMC 바로가기 [Article Type] Article
The quality of systematic reviews and other synthesis in the time of COVID-19Covid-19 시점의 체계적인 검토 및 기타 합성의 품질Article Published on 2021-08-032022-08-31 Journal: Epidemiology and Infection [Category] MERS, meta-analysis, [키워드] Algorithm carried COVID-19 database domain eight evaluate evaluated expected identify impacted increase in knowledge knowledge synthesis Meta-analysis methodology Prevent produced Research responsibility review risk of bia SARS-CoV-2 systematic review systematic reviews Validity [DOI] 10.1017/S0950268821001758 PMC 바로가기 [Article Type] Article
Behavioural nudges increase COVID-19 vaccinations행동 누드는 Covid-19 백사학을 증가시킵니다Article Published on 2021-08-022022-08-13 Journal: Nature [Category] 임상, 치료법, [키워드] behavioural Behavioural intervention behavioural interventions behavioural nudge behavioural nudges Controlled trial COVID-19 vaccination COVID-19 vaccines Critical Decision making dose effective effective communication eight Enhancing Evidence failure first randomized controlled trial greater Health Healthcare system highlight Human behaviour IMPROVE notification outcome ownership participant percentage points performed pilot-testing intervention pilot-testing interventions public health Randomized Randomized controlled trial second randomized controlled trial text-based reminder text-based reminders the vaccine vaccination vaccination intention vaccination intentions vaccination rate Vaccine vaccine dose vaccine eligibility Vaccine hesitancy Vaccines video-based information intervention [DOI] 10.1038/s41586-021-03843-2 PMC 바로가기 [Article Type] Article
An early experience of COVID-19 disease in pediatric and young adult renal transplant recipients소아 및 젊은 성인 신장 이식 수혜자의 COVID-19 질병 초기 경험Case Reports Published on 2021-08-012022-09-12 Journal: Pediatric transplantation [Category] MERS, SARS, 진단, [키워드] AKI Atypical Case report case sery caused children comparable coronavirus COVID COVID-19 COVID-19 disease diagnosis of COVID-19 eight Fever Hospitalization hypoxia IgG antibody Immunocompromised management Mild-to-moderate more difficult New outcome Patient patients pediatric pediatrics recipient recipients renal Renal transplant resolved SARS-CoV-2 Severe respiratory distress solid organ transplant supportive care Symptom Symptoms the patient treated upper respiratory infection variety [DOI] 10.1111/petr.13972 PMC 바로가기 [Article Type] Case Reports
Case series of COVID-19 in patients with myasthenia gravis: a single institution experience중증 근무력증 환자의 COVID-19 사례 시리즈: 단일 기관 경험Article Published on 2021-08-012022-09-12 Journal: Acta neurologica Belgica [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome Administered Admission benefit case sery cause caused Complete coronavirus Coronavirus disease 2019 COVID 19 COVID-19 COVID-19 in patient COVID-19 patient diagnosed died discharged eight greater Hospitalized Immunosuppression Immunosuppressive medication intensive care intravenous immunoglobulin treatment mechanical ventilation Myasthenia myasthenia gravis Neuromuscular Neuromuscular disorders one patient outbreak outcomes Oxygen therapy Patient patients patients with COVID-19 required Respiratory disease Respiratory Support risk Safe SARS-CoV-2 Seven severe disease course Support Symptom Symptoms treated Treatment Treatment outcome worsening [DOI] 10.1007/s13760-021-01662-w PMC 바로가기 [Article Type] Article
Inflammatory biomarkers in COVID-19-associated multisystem inflammatory syndrome in children, Kawasaki disease, and macrophage activation syndrome: a cohort studyResearch article Published on 2021-08-012022-10-05 Journal: The Lancet Rheumatology [Category] 바이오마커, [키워드] Acute kidney injury Altered mental status Analysis approach Biomarker center characteristic chemokine children Cincinnati clinical Coagulopathy cohort of patient cohort study Concentration concentrations conditions CXCL9 Deutsche Forschungsgemeinschaft diagnosed Diagnosis eight elevated ELISA enrolled family finding FIVE foundation Frequency funding Hyperinflammatory Hyperinflammatory syndrome IL-18 IL-6 Inflammatory Inflammatory biomarker juvenile idiopathic arthritis Kawasaki disease Laboratory laboratory feature Ligand macrophage activation macrophage activation syndrome management median median age MIS-C motif Myocardial dysfunction nine non-parametric test occur Pathogenesis pathophysiology Patient potentially life-threatening prospective cohort Protein provide S100A12 SARS-COV-2 infection Sensitivity and specificity Seven severity Shock significantly higher skin Stratification Support syndrome systemic inflammatory marker USA was done were assessed [DOI] 10.1016/S2665-9913(21)00139-9 [Article Type] Research article