A Five-Ingredient Nutritional Supplement and Home-Based Resistance Exercise Improve Lean Mass and Strength in Free-Living Elderly5가지 성분의 영양 보조제 및 가정 기반 저항 운동으로 자유 생활 노인의 제지방 및 근력 향상Article Published on 2020-08-102022-08-13 Journal: Nutrients [Category] 임상, [키워드] age anabolic Analysis body fat casein collagen Combination complement conditions COVID-19 creatine cross-sectional area desensitization double-blind trial Effect effective Efficacy elderly examined exercise fat fatty acids fiber greater grip IMPROVE indicated individual lean mass leg press lower physical activity levels mass men MIS multi-ingredient supplement muscle fiber muscle loss muscle mass old age Older omega-3 Omega-3 fatty acids physical activity levels Placebo placebo-controlled post intervention PROTECT Protein quadricep Randomized randomized clinical trial resistance resistance exercise Safe sarcopenia sarcopenic significantly significantly increased Stand strength sunflower oil therapy Type Vitamin D whey [DOI] 10.3390/nu12082391 PMC 바로가기 [Article Type] Article
Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic DonorsArticle Published on 2020-08-072022-10-28 Journal: Biology [Category] COVID-19, [키워드] ACE2 ACE2 expression ADAM17 adipose age binding BMI cells correlated COVID-19 diabete diabetes Diabetic diabetics Donor donors Endocrine entry of SARS-CoV-2 explain Express expression expression data expression level expression pattern female Gender Human human islets islet islets Microarray not affected occur pancreatic pancreatic islet pancreatic islets patients priming profile promote receptor required Revealed RNA-Seq RNA-sequencing S1 protein SARS-CoV-2 severity of COVID-19 significantly higher significantly increased statistically Symptom T2D the S protein thought tissue TMPRSS2 TMPRSS2 expression Variation viral spike [DOI] 10.3390/biology9080215 PMC 바로가기 [Article Type] Article
Poor Prognostic Biochemical Markers Predicting Fatalities Caused by COVID-19: A Retrospective Observational Study From a Developing CountryInternal Medicine Published on 2020-08-052022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Admission age Analysis biochemical marker Biomarker Biomarkers C-reactive protein Cell conducted coronavirus coronavirus disease Course COVID-19 COVID-19 positive patient creatinine CRP CRP level D-dimer D-dimer level Developing discharge disease effective elevated fatality female patient ferritin Health hemoglobin hospital hypernatremia IBM identify Infectious diseases intensive care Isolation Laboratory laboratory investigation lactate dehydrogenase LDH leukocyte Leukocytosis Lymphocyte count lymphocytopenia male marker material monocyte Mortality neutrophil count non-survivor outcome Pakistan pandemic Patient patients patients died PCT Platelet Poor Predictive procalcitonin Prognosis receiver operating characteristic recovered patients Result resulting retrospective SARS-CoV-2 serum severity shown significant difference significantly significantly increased sodium SPSS Statistics study population survived survivor the disease urea Version Volume was done window World Health Organization [DOI] 10.7759/cureus.9575 PMC 바로가기 [Article Type] Internal Medicine
Dynamic changes in clinical and CT characteristics of COVID-19 cases with different exposure histories: a retrospective studyResearch Article Published on 2020-08-032022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] absorbed Admission albumin Beijing C-reactive protein Capital changes in Characteristics clinical characteristic Contact correlated cough COVID-19 COVID-19 case COVID-19 patient CRP CT Different exposure histories discharge discharged disease severity dynamic Dynamic change early diagnosis elevated enrolled Epidemiology expected fatigue Follow-up ground-glass opacity group initial Laboratory lung lesion Lymphocytes lymphopenia majority pathogenicity Patient patients predict Prognosis progression reduced Result Retrospective study significantly increased significantly lower Spearman correlation analysis Travel university was performed Wuhan [DOI] 10.1186/s12879-020-05306-x PMC 바로가기 [Article Type] Research Article
Efficacy and Safety of Anti-malarial Drugs (Chloroquine and Hydroxy-Chloroquine) in Treatment of COVID-19 Infection: A Systematic Review and Meta-AnalysisMedicine Published on 2020-07-292022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Administered adverse event adverse events aminoquinoline anti-malarial drug Anti-malarial drugs arrhythmia Azithromycin cardiac event carried Chloroquine clinical trial Combination coronavirus COVID-19 COVID-19 infection database drug ECG Effect Efficacy eight evaluated Evidence Evidence-based medicine Good HCQ Hospitalized Hydroxychloroquine In-vitro increased risk Infection inhibit laboratory parameter Major material Meta-analysis Mortality no significant effect non-randomized trial observational studies OSF outcome outcome measure pandemic participant Participants patients Primary outcome provided QT prolongation RCT reached Registration required review risk Safety SARS-CoV-2 secondary significantly increased systematic review Treatment with COVID-19 [DOI] 10.3389/fmed.2020.00482 PMC 바로가기 [Article Type] Medicine
Emotional Eating in Pregnant Women during the COVID-19 Pandemic and Its Association with Dietary Intake and Gestational Weight GainArticle Published on 2020-07-282022-10-30 Journal: Nutrients [Category] COVID-19, SARS, [키워드] 2019 coronavirus disease 95% CI activities adjusted affected association average Behavior body mass index changed China Chinese confidence COVID-19 COVID-19 pandemic determine dietary dietary change Dietary changes dietary intake disease domain eating emotional emotional eating evaluated examined Gain gestational weight gain Health Impact indicated information intake interval Intervention less lockdown mediation model metabolic disease mother occurred Outbreaks pandemic participant physical physical activity predictor Pregnancy pregnant women public health Ratio recruited sensitivity analysis Seven significantly increased Sociodemographic characteristics triggered was used weight women Wuhan [DOI] 10.3390/nu12082250 PMC 바로가기 [Article Type] Article
Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic reviewResearch Published on 2020-07-282022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] 95% CI Abstract Admission Analysis arrhythmia article Biomarker Biomarkers cardiac injury Chinese CK-MB CNKI Cochrane Library coronavirus disease COVID-19 COVID-19 patient database death elevated higher risk hospitalized patient ICU ICU admission IL-6 IL-6 level IL-6 levels independent predictor individuals Infrastructure Injury intensive care interleukin-6 investigator investigators lactate dehydrogenase LDH medRxiv Meta-analysis Mortality Myocardial Patient Prognosis proportion Result risk searched severe disease significantly higher significantly increased systematic review TnI troponin I [DOI] 10.1186/s13054-020-03183-z PMC 바로가기 [Article Type] Research
Ultraviolet A light effectively reduces bacteria and viruses including coronavirusResearch Article Published on 2020-07-162022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] alveolar Bacteria Candida albican Cell cell death changes in clinical Clostridioide colonic conditions Controlled controls coronavirus coronavirus spike protein coxsackievirus disease DNA damage dysplastic Effect effective Efficacy effort Enterococcus epithelial Escherichia coli exhibited growth had no Hela HeLa cell histologic human cell human cells humans in vitro in vivo in vivo model Infectious disease investigated Klebsiella pneumoniae marker mice mitochondrial antiviral-signaling protein oxidative pathogen produced Proteus Pseudomonas aeruginosa reduce reduction reductions in regimens repeated Safe significant effect significantly increased Specific Staphylococcus epidermidis Streptococcus pyogene survival Therapies tissue tracheal treat Treatment ultraviolet A viability virus was measured wild-type yeast [DOI] 10.1371/journal.pone.0236199 PMC 바로가기 [Article Type] Research Article
Clinical Characteristics and Immune Injury Mechanisms in 71 Patients with COVID-19Research Article Published on 2020-07-152022-10-30 Journal: mSphere [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition analyzed B lymphocytes Bacterial C-reactive protein C1q cause caused CD16 CD19 CD3 CD4 CD56 CD8 China clinical complement coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical death dysregulation early stage electronic medical record eosinophil Excessive activation Health hematological parameters hemoglobin IL-6 immune immune dysregulation immunological characteristics IMPROVE Infection Inflammatory cytokine Inflammatory cytokine storm inflammatory storm laboratory data Lymphocyte count mechanism Mild mortality rate National Health Commission Neutrophils NHCC NK cell NK cells Novel coronavirus outbreak parameters particularly prominent in Pathogens Patient patients Peripheral blood procalcitonin provide SARS-CoV-2 severe cases severely ill patient significantly significantly increased stratified T lymphocytes with COVID-19 [DOI] 10.1128/mSphere.00362-20 PMC 바로가기 [Article Type] Research Article
Redefining Cardiac Biomarkers in Predicting Mortality of Inpatients With COVID-19COVID-19 입원 환자의 사망률 예측에서 심장 바이오마커 재정의Multicenter Study Published on 2020-07-142022-09-25 Journal: Hypertension (Dallas, Tex. : 1979) [Category] MERS, SARS, 바이오마커, 진단, [키워드] 28-day mortality adjusted hazard ratio age assist association Biomarker Biomarkers Brain cardiac cardiac injury marker cardiac troponin circulating clinical trials Comorbidities content coronavirus disease COVID-19 COVID-19 patient Cox model criteria Cutoff cutoff value death defined diagnosed Digital disease effective elevated Elevation enrolled Heart diseases heart injuries hospital IMPROVE Inpatient management Mortality much lower Myoglobin N-terminal outcome outcomes Patient patients with COVID-19 peptide pro-B-type natriuretic peptide Prognosis prognostic Prospective Study Retrospective study risk of COVID-19 Sex significantly significantly increased thresholds utility [DOI] 10.1161/HYPERTENSIONAHA.120.15528 PMC 바로가기 [Article Type] Multicenter Study