Engaging With Communities — Lessons (Re)Learned From COVID-19Commentary Published on 2020-07-162022-10-29 Journal: Preventing Chronic Disease [Category] COVID-19, SARS, [키워드] changes in Community Coronavirus disease 2019 COVID-19 demonstrated disease dissemination driver engage equity Health highlight implementation lesson Local Prevent promote public health sustained [DOI] 10.5888/pcd17.200250 PMC 바로가기 [Article Type] Commentary
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research EthicsPerspective Published on 2020-07-152022-10-30 Journal: mSphere [Category] Coronavirus, SARS, [키워드] challenge Challenge studies coronavirus coronavirus disease COVID-19 disease-causing dissemination Ethics expected global health Human Infection occur offer outbreak participant Research Research Ethics suggested Test Trial Vaccine value [DOI] 10.1128/mSphere.00669-20 PMC 바로가기 [Article Type] Perspective
Effects of Health Information Dissemination on User Follows and Likes during COVID-19 Outbreak in China: Data and Content AnalysisArticle Published on 2020-07-142022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] affected Analysis article attacked characteristic Characteristics China coding collected content content analysis contribute coronavirus COVID-19 dissemination Effect feature Frequency health information health information dissemination Impact impacted information Like media Novel coronavirus official account pandemic positive Regression model user users’ information behavior was used website WeChat [DOI] 10.3390/ijerph17145081 PMC 바로가기 [Article Type] Article
Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, CanadaLetter Published on 2020-07-142022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 1:1 Activation age All participants anticipated baseline blinded block sizes blocked blood sample Canada Chloroquine circulating cirrhosis clinical clinician composite endpoint computer-generated Concomitant medication correlation Course COVID-19 COVID-19 negative criteria deficiency determine diabete diagnostic disease severity dissemination ECG element Encephalopathy endothelial Enrollment extension FIVE fixed Follow-up G6PD HCQ HCW Health care worker Hepatitis high risk hospital Hospitalization Hospitalized Host Hydroxychloroquine immune include individually randomized insulin intensive care units Intervention intervention arm intubation investigator Laboratory Liver disease Long marker microbiologically Mortality multisite neutralize non-invasive ventilation non-specific number objective offered Older open label Oropharyngeal outcome outcome measure parallel-group participant patients per day Placebo placebo-controlled plasma porphyria positive positive result pregnant Prevent Primary outcome Prophylaxis Protecting protocol Psychological distress psychological Impact QTc QTc interval randomised randomised placebo controlled trial reactive reduce Registered renal reported Research Respiratory failure risk of COVID-19 Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus secondary Seroconversion serology Standard status study period Study protocol Support symptom duration symptomatic syndrome Tablet tablets term Toronto Trial two group Two-arm undergo use of hydroxychloroquine ventilator viral PCR Viral RNA website worker [DOI] 10.1186/s13063-020-04577-8 PMC 바로가기 [Article Type] Letter
Restructuring ENT out-patient services during the coronavirus disease 2019 pandemic – an iterative approachMain Articles Published on 2020-07-142022-10-30 Journal: The Journal of laryngology and otology [Category] COVID-19, MERS, SARS, [키워드] aerosol-generating procedure analysed Analysis approach collected conducted coronavirus coronavirus disease Coronavirus disease 2019 data-driven dissemination dropped iterative National Health Service objective occurred otolaryngology Otorhinolaryngologic Surgical Procedures outcome outpatients pandemic Pandemics performed persists recommendation required restructuring Result service study period [DOI] 10.1017/S0022215120001450 PMC 바로가기 [Article Type] Main Articles
Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial호흡 조절 및 요가 운동 COVID-19 대유행을 관리하는 최전선 병원 및 장기 요양원 직원을 위한 평온과 행복을 위한 온라인 치료(BREATH): 무작위 대조 시험에 대한 타당성 연구를 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-07-142022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 active treatment All study participant All study participants allocation concealment Analysis Anxiety ARMS blinded Blinding breath breaths Canada Care collected Complete Completeness completion consent form control arm Controlled trial COVID-19 COVID-19 pandemic COVID-19 patient data entry Depression determine dissemination element eligibility English enhancement exercise feasibility feasible foundation Group allocation Health Health promotion Healthcare staff healthcare worker Healthcare workers healthy hospital IMPROVE include Insomnia interactive module Intervention involved London Long-term care management measure medium mental health mind-body intervention mindfulness Mindfulness-based muscle relaxation music therapy number objective offered online session Open-label outcome participant phase Phase I physical Prevent Program progressive muscle relaxation promotion protocol Psychoeducation randomised randomised controlled trial randomization randomize Randomized Randomized controlled trial RCT recruited recruitment REDCap reduce Research researcher Resilience resiliency retention Sample size scheduling significantly status study hypothese study hypotheses Study protocol subsequent supervision therapy Treatment Trial USA website Weekly windows Work stress yoga [DOI] 10.1186/s13063-020-04583-w PMC 바로가기 [Article Type] Letter
The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-07-142022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 48 hour addition Administered adverse effect allergy Alpha anticipated assumed baseline blinded to treatment block clinical Clinical outcome Comorbidity COVID-19 data management Day death determine dissemination drug interaction element eligible eligible participant enrolment evaluate evaluated excluded expected group hospital hospitalised hospitalised patient Hydroxychloroquine independent Intensive intensive care Intervention intervention arms invasive investigator investigator-initiated Laboratory Lopinavir management men New no interaction non-invasive ventilation nucleic acid number objective Open-label outcome participant Patient platform Primary outcome proportion Proportion of participant protocol provided QTC prolongation randomisation randomised randomised controlled trial receive receiving recruited reduce Registered registry representing required researcher Respiratory Support risk Ritonavir Sample size SARS-CoV-2 SARS-COV-2 infection secondary outcome sequence significance level Standard of care status stratified study drug Study protocol Tablet total sample size treated Trial two-sided unblinding ventilatory support Virological website women [DOI] 10.1186/s13063-020-04576-9 PMC 바로가기 [Article Type] Letter
Temperature Sensitivity: A Potential Method for the Generation of Vaccines against the Avian Coronavirus Infectious Bronchitis VirusArticle Published on 2020-07-142022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Accessory genes affected allelic antigenic clone contagious core body temperature coronavirus days post infection defined determinant determine dissemination effectively deliver eyelid function Generation Genes genetics Host IBV in vivo Infectious Bronchitis Virus investigated lesion molecular mRNA synthesis Mutation pathogenic Potential Proteins replicase replicate respiratory pathogen RNA synthesis sensitivity Seven strain temperature temperature sensitive temperature sensitivity tissue upper respiratory tract Vaccine design Vaccine development vaccine platform viral replication was used [DOI] 10.3390/v12070754 PMC 바로가기 [Article Type] Article
A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-07-132022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 24 hour 48 hour Activation acute lung injury acute pneumonia acute respiratory distress syndrome Administered Adult age all-cause mortality Amendment antibodies antibody Antibody test anticipated antiviral therapy approval ARDS assessment assigned baseline Biomarker Blood cardiac disease Care change class Clinical improvement clinical study clinical trial complement Complement inhibitor component Computed tomography concealed Concentration conducted Confirmed Controlled coronary syndrome COVID-19 criteria current Day diagnosis of SARS-CoV-2 dialysis discharge dissemination dose Duration Efficacy element eligibility Endotracheal intubation EU Clinical Trial EudraCT evaluate the effect expected failure female patient Final fraction France Germany greater half-live hospital Hospitalization humanized Hypercoagulable state Immunoglobulin Infection Inflammatory inhibitor initiated intensive care Intubated intubation invasive Invasive mechanical ventilation investigator IVIG Japan Lung injury mechanical ventilation medication monoclonal multicenter Neisseria meningitidis Non-invasive number objective Open-label original outcome oxygen participant Patient patients randomized patients with COVID-19 Period peripheral capillary phase Placebo Pneumonia polymerase chain positive airway pressure presenting progression protocol randomised randomised controlled trial randomization randomization list Randomized randomized controlled study Randomly Ravulizumab receive recruitment registry Remdesivir renal respiratory respiratory distress Respiratory distress syndrome routine clinical care Safety screened Screening secondary Serious Adverse Events serum severe acute respiratory distress syndrome coronavirus 2 Severe acute respiratory syndrome severe COVID-19 severe pneumonia SOFA Spain SpO2 Sponsor stratified Study protocol supportive care survival The United States therapy time Treatment treatment-emergent adverse event Ultomiris United Kingdom ventricular Viral website with COVID-19 X-ray [DOI] 10.1186/s13063-020-04548-z PMC 바로가기 [Article Type] Letter
Test and treat COVID 65 plus – Hydroxychloroquine versus placebo in early ambulatory diagnosis and treatment of older patients with COVID19: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-07-102022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] adaptive adhere age ambulatory anticipated blinded block randomization calculated cardiac Care Complete concerning COVID COVID-19 COVID-19 disease cumulative death defined Diagnosis disease dissemination dose double blind double-blind early treatment elderly patients element female patient first dose first stage hospital Hospitalization Hydroxychloroquine identify Inclusion interim analysis investigators Mental Mild moderate moderate disease number objective older patient outcome Outpatient participant Patient patients PCR physician Placebo placebo-controlled positive produced protocol provided randomised randomised controlled trial randomization randomization list Randomly Rate recruited respiratory rate risk Sample size SARS-CoV2 Septic shock Side effects SpO2 status stratified study inclusion Study protocol study visit Symptom symptom onset Test throat swab Total total sample size treat Treatment Trial Tübingen Ulm website with COVID-19 [DOI] 10.1186/s13063-020-04556-z PMC 바로가기 [Article Type] Letter