significantly increased – Page 64 – Communicable Diseases Research

D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: a case control study

Research

Published on 2020-07-102022-10-30
Journal: Journal of Intensive Care [Category] COVID-19,

[키워드] 95% CI Admission analyzed AUC Biomarker case control study Characteristics Chest CT Clinical outcome Coronavirus disease-19 COVID-19 COVID-19 patient Cutoff D-dimer D-dimer elevation D-dimer level determine disease severity elevated Hospitalization in-hospital mortality Laboratory Mortality mortality rate multivariable logistic regression Multivariable regression non-survivor over Patient patients patients with COVID-19 predicted Probability Prognostic marker Pulmonary embolism radiological receiver operating characteristic Renmin Hospital reported Result risk factor sensitivity severity severity of COVID-19 significantly higher significantly increased specificity survivor thrombosis university was used were used Wuhan Wuhan, China
[DOI] 10.1186/s40560-020-00466-z PMC 바로가기 [Article Type] Research

Incidence of Stress Cardiomyopathy During the Coronavirus Disease 2019 Pandemic

Research

Published on 2020-07-092022-10-29
Journal: JAMA Network Open [Category] COVID-19, SARS,

[키워드] 95% CI age analyzed Cardiomyopathy catheterization Cleveland clinic cohort study control group coronary syndrome coronavirus disease COVID-19 COVID-19 pandemic determine examined exposure finding group health system hospital Hospitalized Importance incidence increase in interquartile range Laboratory measure median men Mortality no significant difference objective outcome pandemic participant Patient Percutaneous coronary intervention Point presenting proportion Psychological ranged rehospitalization Relevance Result retrospective cohort study setting significant increase significantly increased Stress syndrome timeline timelines
[DOI] 10.1001/jamanetworkopen.2020.14780 PMC 바로가기 [Article Type] Research

LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2

Virus-Cell Interactions

Published on 2020-07-082022-10-30
Journal: Journal of Virology [Category] COVID-19, MERS,

[키워드] A549 cell ADAP2 adaptive immune responses Analysis Antigen Antiviral Cell cell line cell tropism cells cellular Contact Control coronavirus Coronavirus infection CoV CoV infection Critical determinant domain ectopic expression Efficiency effort expand expression facilitate Factor Fever growth HCoV-OC43 hepatoblastoma HepG2 HepG2 cells homology Host host cell host range Human human coronavirus human coronaviruses Human immunodeficiency virus identification IFITM3 IFITMs immune Immunopathogenesis Including Infection influenza A virus inhibited knockdown LY6E lymphocyte mechanism modulate neutralized overexpression pandemic Pathogenesis Protein Proteins reported restriction factor SARS-CoV-2 serine protease TMPRSS2 significantly significantly higher significantly increased Spike protein susceptibility susceptible transmembrane Treatment variety viral entry virus virus entry viruses were expressed while
[DOI] 10.1128/JVI.00562-20 PMC 바로가기 [Article Type] Virus-Cell Interactions

Using IL-2R/lymphocytes for predicting the clinical progression of patients with COVID-19

Article

Published on 2020-07-012022-10-06
Journal: Clinical and experimental immunology [Category] SARS, 진단,

Prognosis analysis of patients with mental disorders with COVID-19: a single-center retrospective study

Research Paper

Published on 2020-06-302022-10-28
Journal: Aging (Albany NY) [Category] COVID-19, SARS,

“Small” Intestinal Immunopathology Plays a “Big” Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor

Immunology

Published on 2020-06-262022-10-31
Journal: Frontiers in Immunology [Category] COVID-19, MERS,

[키워드] accompanied administration affected antibodies Antigen blood pressure bowel caused characterized contribute contributed coronavirus disease COVID-19 CRS cytokine cytokine production Cytokine release syndrome deficiency Degradation down-regulated expression Extracellular matrix HLA class II transgenic mice HLA-DR3 IFN-γ IL-17A immune Immunopathogenesis immunopathology indicated inflammatory pathway inhibitor inhibitors intestinal intestinal tissue JAK inhibitor janus kinase lethal maintain mice Mortality multiple organ multiple organ dysfucntion multiple organ dysfunction organ organ function pathogenic pathology pathway pro-apoptotic receptor Release RNA sequencing role SARS-CoV-2 selective severity signaling pathway significantly significantly increased specific treatment staphylococcal superantigens Support systemic level T cell T cell activation therapy Toxic shock syndrome transgenic mice Treatment TSS
[DOI] 10.3389/fimmu.2020.01311 PMC 바로가기 [Article Type] Immunology

Clinical characteristics of Coronavirus Disease 2019 patients in Beijing, China

중국 베이징의 코로나 바이러스 질병 2019 환자의 임상 특성

Research Article

Published on 2020-06-172022-08-13
Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS,

[키워드] addition affected age albumin anorexia average average age Beijing C-reactive protein Characteristics China clearance rate clinical clinical feature Clinical studies clinical study Confusion coronavirus coronavirus disease country COVID-19 creatinine creatinine clearance expectoration high systolic blood pressure hospital ICU incidence lymphocyte Lymphocytes median Myoglobin neutrophil Neutrophils Older older patient older patients outbreak oxygen oxygen saturation Patient patients patients died patients with COVID-19 Region retrospective cohort study severe severe disease Severe patient severe patients Shortness of breath significantly significantly increased significantly lower Systolic blood pressure the disease the patient troponin I Wuhan
[DOI] 10.1371/journal.pone.0234764 PMC 바로가기 [Article Type] Research Article

Immunization with porcine epidemic diarrhea virus harbouring Fc domain of IgG enhances antibody production in pigs

Research Article

Published on 2020-06-082022-10-28
Journal: The Veterinary Quarterly [Category] Coronavirus, MERS,

[키워드] addition Analysis antibody production Cell collected coronavirus crossbred cytokine domain Efficacy ELISA ENhance epidemic diarrhea evaluated experiment expressing facilitate Fc IFN-γ IgG IgG Fc immune response immunization inactivated Inactivated vaccine Infection intramuscularly negative controls Neutralizing objective PEDV Porcine Porcine epidemic diarrhea Prevent Protective Result resulting sera serum serum sample significantly higher significantly increased Spread swine t-test TCID two-tailed Vaccine vaccine candidate Vero Cell virion virus was performed were used
[DOI] 10.1080/01652176.2020.1773006 PMC 바로가기 [Article Type] Research Article

Characteristic of COVID-19 infection in pediatric patients: early findings from two Italian Pediatric Research Networks

Short Communication

Published on 2020-06-032022-10-31
Journal: European journal of pediatrics [Category] COVID-19, MERS, SARS,

The social psychological impact of the COVID-19 pandemic on medical staff in China: A cross-sectional study

Research Article

Published on 2020-06-012022-10-31
Journal: European Psychiatry [Category] COVID-19, SARS,