Comparison of an inactivated Covid19 vaccine-induced antibody response with concurrent natural Covid19 infection비활성화된 Covid19 백신 유도 항체 반응과 동시 자연 Covid19 감염의 비교Article Published on 2021-12-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] age Anti-N anti-N antibodies anti-N antibody anti-S Anti-S1 antibodies antibody Antibody Response Antibody testing Antibody titer Antibody titers both groups COVID-19 infection COVID19 decrease detect disadvantage ELISA enrolled Euroimmun Gender Germany group HCW HCWs Health care Health care worker health care workers IgG inactivated increase in Infection median value median values Patient patient group patient groups positive correlation reported risk Roche SARS-CoV-2 Seroconversion statistically significant statistically significant difference the antibody the antibody response the patient the vaccine total Ig vaccinated individual vaccinated individuals vaccination Vaccine vaccine-induced antibody response were used [DOI] 10.1016/j.ijid.2021.09.060 PMC 바로가기 [Article Type] Article
Long-term humoral immunogenicity, safety and protective efficacy of inactivated vaccine against COVID-19 (CoviVac) in preclinical studies전임상 연구에서 코로나19 불활화 백신(CoviVac)의 장기 체액성 면역원성, 안전성 및 보호 효능Article Published on 2021-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] SARS, 신약개발, 진단, [키워드] allergenic animal model animal models anti-SARS-CoV-2 IgG clinical trial clinical trials country Course COVID-19 COVID-19 pandemic decrease demonstrated Effects Efficacy hamster hamsters humoral immune response humoral immunogenicity immune response immunization immunogenicity implementation inactivated Inactivated vaccine intranasal Live virus mice multitude NAb NAbs Neutralizing Neutralizing antibodies non-human primates preclinical study Protective reproductive robust robustness rodent rodents Safety SARS-CoV-2 severe pneumonia significantly stability teratogenic teratogenic effects the vaccine the vaccines These data Toxicity Vaccine vaccine platform virion [DOI] 10.1080/22221751.2021.1971569 PMC 바로가기 [Article Type] Article
Previous COVID-19 Infection and Antibody Levels After Vaccination이전 백신 접종 후 COVID-19 감염 및 항체 수준Public Health Published on 2021-12-012022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, [키워드] adjusted Analysis antibodies antibody antibody levels association average BNT162b2 ChAdOx1 ChAdOx1 vaccine ChAdOx1 vaccines Characteristics circumvent Comorbidities Comorbidity country COVID-19 COVID-19 infection COVID-19 infections COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines distribution dose effort elicit followed by generalized linear regression greater health authorities high risk Humoral immunity Humoral response IgA IgG Immunoglobulin individual Infection Kuwait Level Neutralizing antibodies neutralizing antibody protocol public health authority recruited Regression regression analysis robust SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody serological analysis student subject sustained t -test the vaccine vaccinate vaccinated individual vaccinated individuals vaccination Vaccine variants of concern was performed [DOI] 10.3389/fpubh.2021.778243 PMC 바로가기 [Article Type] Public Health
Factors Associated With COVID-19 Vaccine Receipt by Health Care Personnel at a Major Academic Hospital During the First Months of Vaccine AvailabilityResearch Published on 2021-12-012022-10-29 Journal: JAMA Network Open [Category] COVID-19, SARS, [키워드] 95% CI African American age Asian Better black Care collected Contact COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional doses driving Ethnic groups Evidence exposure Factor finding first dose had no hcp Health help Hispanic hospital Importance IMPROVE less Major measure men Month Nurse objective offered participant Patient Philadelphia physician Physicians Point Racial receipt receive Relevance Result risk setting Sex stratified study population the vaccine vaccination Vaccine vaccine availability vaccine dose Vaccine hesitancy white women [DOI] 10.1001/jamanetworkopen.2021.36582 PMC 바로가기 [Article Type] Research
Qualification of ELISA and neutralization methodologies to measure SARS-CoV-2 humoral immunity using human clinical samplesResearch Paper Published on 2021-12-012022-10-30 Journal: Journal of Immunological Methods [Category] COVID-19, SARS, [키워드] 2019-nCoV/USA-WA1/2020 Abstract antibody Antibody titer Antigen assays clinical clinical sample Complete control sample convalescent COVID COVID-19 Efficacy ELISA ELISAs Endpoint evaluate evaluated functional healthy donor human clinical trials humoral humoral immune response Humoral immunity IgA IgG IgG1 IgG3 IgG4 IgM Image in vitro individuals inhibiting lentivirus linear linearity magnitude methodology neutralization Neutralizing Neutralizing titer pandemic plaque reduction neutralization plasma PRNT pseudovirus Pseudovirus neutralization assay Qualification RBD Receptor binding domain Replication response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 vaccine the SARS-CoV-2 the Spike the vaccine trials trimeric spike Vaccine WHO [DOI] 10.1016/j.jim.2021.113160 PMC 바로가기 [Article Type] Research Paper
Automatic detection of COVID-19 vaccine misinformation with graph link prediction그래프 링크 예측으로 코로나19 백신 잘못된 정보 자동 감지Article Published on 2021-12-012022-09-11 Journal: Journal of biomedical informatics [Category] SARS, 치료기술, 치료제, [키워드] addition Automatic automatic detection automatically COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines dataset detect Efficacy experimental results exposure to function Hesitancy highest Intervention knowledge Knowledge graph knowledge graph embedding language machine machine learning media misinformation natural natural language natural language processing platform provided social media Spread target the vaccine Vaccine Vaccine hesitancy vaccine misinformation. Vaccines Volume [DOI] 10.1016/j.jbi.2021.103955 PMC 바로가기 [Article Type] Article
The role of trust in the likelihood of receiving a COVID-19 vaccine: Results from a national surveyResearch article Published on 2021-12-012022-10-05 Journal: Preventive medicine [Category] SARS, 변종, [키워드] approval building chronic conditions coronavirus disease COVID-19 COVID-19 vaccine COVID-19 vaccines Critical domain Efficacy and safety Essential workers explained healthcare individual Lack of trust less likelihood National Older Older adults pandemic Racial/ethnic minorities receiving Result subgroup subgroups the vaccine Trust Underserved communities vaccination Vaccine Vaccine development Variation women [DOI] 10.1016/j.ypmed.2021.106727 [Article Type] Research article
A Next-Generation Vaccine Candidate Using Alternative Epitopes to Protect against Wuhan and All Significant Mutant Variants of SARS-CoV-2: An Immunoinformatics ApproachOriginal Article Published on 2021-12-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] added antigenic epitope applied approach B cell B.1.1.28 B.1.1.7 B.1.351 bioinformatics boost immunity candidate codon optimization computational tools country demonstrated develop epitope expression flexible host immune system identify immunoinformatics In silico cloning Interaction linker molecular molecular docking analysis multi-epitopes mutagenic mutant mutant variants N-terminal next-generation vaccine parameter peptide peptide vaccine peptide-based physicochemical property Region SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants second wave Significant stability T cell epitopes the vaccine Vaccine vaccine candidate vaccine construct variant variants variants of SARS-CoV-2 VoC were assessed were used Wuhan [DOI] 10.14336/AD.2021.0518 PMC 바로가기 [Article Type] Original Article
SARS-CoV-2 vaccine effectiveness in preventing confirmed infection in pregnant women임산부에서 확인된 감염 예방에 SARS-CoV-2 백신 효과Article Published on 2021-12-012022-09-11 Journal: The Journal of Clinical Investigation [Category] SARS, 변종, [키워드] 95% CI 95%CI adjusted Adjustment age Alpha variant Analysis Beta Beta variant Case-control Cohort cohort analysis Complication Control analysis Corporation COVID-19 Critical disease death disease distress during pregnancy Effectiveness Epidemiology first dose gestational age higher risk hospital Hospitalization Inclusion Infection Infectious disease Medicine mRNA vaccine mRNA vaccines National nationality Neonatal Pregnancy pregnant women Public respiratory distress SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose Support the vaccine vaccination Vaccine variant variants women [DOI] 10.1172/JCI153662 PMC 바로가기 [Article Type] Article
Implications of attitudes and beliefs about COVID-19 vaccines for vaccination campaigns in the United States: A latent class analysisResearch article Published on 2021-12-012022-10-05 Journal: Preventive Medicine Reports [Category] 변종, [키워드] Analysis approval conducted COVID-19 COVID-19 vaccine COVID-19 vaccine development Critical effective vaccine Effectiveness English global effort group identify individual latent class latent class analysis likelihood pandemic participant positive profile proportion public health question resulting the vaccine United State vaccination Vaccine Vaccine development vaccine intentions Vaccines [DOI] 10.1016/j.pmedr.2021.101584 [Article Type] Research article