Central Nervous System Manifestations Associated with COVID-19Article Published on 2020-10-302023-06-15 Journal: Current neurology and neuroscience reports [Category] MERS, SARS, [키워드] cns manifestations COVID-19 neurological manifestations pandemic SARS-CoV-2 stroke [DOI] 10.1007/s11910-020-01079-7 PMC 바로가기
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibitionArticle Published on 2020-10-292022-10-06 Journal: Blood [Category] SARS, 진단, [키워드] activate Activation acute respiratory syndrome Alternative pathway animal antibody APC Atypical blocked C3c catastrophic cells clinical manifestation complement Complement pathway contagious coronavirus COVID-19 Direct disease end-organ end-organ damage endothelial damage Evidence explain Human Hypothesis in vitro inactivation Injury killing mechanism mice mitigate Myocardial infarction Prevent renal respiratory virus SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 spike proteins Spike protein stroke subunit supernatant syndrome target cells the N protein the SARS-CoV-2 thrombosis Trigger upstream uremic syndrome [DOI] 10.1182/blood.2020008248 PMC 바로가기 [Article Type] Article
Impact of the COVID-19 Pandemic on Emergency Department Use: Focus on Patients Requiring Urgent RevascularizationObservational Study Published on 2020-10-282023-06-16 Journal: The Journal of emergency medicine [Category] MERS, SARS, [키워드] COVID-19 emergency department NSTEMI STEMI stroke TIA [DOI] 10.1016/j.jemermed.2020.09.042 PMC 바로가기 [Article Type] Observational Study
COVID-19 Associated Ischemic Stroke and Hemorrhagic Stroke: Incidence, Potential Pathological Mechanism, and ManagementNeurology Published on 2020-10-272022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] ACE2 ACE2 receptor Angiotensin-converting enzyme Atherosclerosis binding blood pressure caused Cerebrovascular disease Comorbidities COVID-19 COVID-19 patient D-dimer level elevated Evidence healthcare worker Hemorrhagic Stroke immune response increase Increasing induce Infection Infectious disease Inflammatory response Ischemic Ischemic Stroke management nervous system Neurological symptoms Novel coronavirus outbreak pathological Patient patients with COVID-19 Potential reduction risk SARS-CoV-2 SARS-COV-2 infection Spread stroke suggested the cytokine storm the SARS-CoV-2 virus viral infection [DOI] 10.3389/fneur.2020.571996 PMC 바로가기 [Article Type] Neurology
Incidence of Thrombotic Events and Outcomes in COVID-19 Patients Admitted to Intensive Care UnitsInternal Medicine Published on 2020-10-212022-10-31 Journal: Cureus [Category] COVID-19, [키워드] African American African Americans age analyzed Care Caucasian cause Complication coronavirus disease COVID-19 COVID-19 patients Critically ill Critically ill patient cumulative database develop Diagnosis event Evidence false discovery rate females healthcare ICU ICU patient incidence intensive care intensive care unit male material median median age medical record men Mortality mortality rate multiple comparisons Myocardial Older organization outcomes overall mortality Patient patients platform ranged reported Research Result risk factor severe COVID-19 severe disease shown significantly more statistically significant stroke study population thrombosis Thrombotic complications thrombotic event Thrombotic events Venous Thromboembolism VTE while women [DOI] 10.7759/cureus.11079 PMC 바로가기 [Article Type] Internal Medicine
Decrease in Stroke Diagnoses During the COVID-19 Pandemic: Where Did All Our Stroke Patients Go?Viewpoint Published on 2020-10-212022-10-31 Journal: JMIR Aging [Category] COVID-19, [키워드] Admission affected Analysis Antonio average cerebrovascular Cerebrovascular disease Community Complication COVID-19 COVID-19 pandemic decrease diagnose discharge emergency medicine Evidence headache indicated Ischemic Stroke Isolation lethargy Mild symptom mortality rate Patient patients with SARS-CoV-2 Population presenting Region SARS-CoV-2 significantly stroke Symptom the patient these symptom Treatment Volume [DOI] 10.2196/21608 PMC 바로가기 [Article Type] Viewpoint
Rapid Epidemiological Analysis of Comorbidities and Treatments as risk factors for COVID-19 in Scotland (REACT-SCOT): A population-based case-control studyResearch Article Published on 2020-10-202022-10-29 Journal: PLoS Medicine [Category] COVID-19, MERS, SARS, [키워드] 95% CI acting acute respiratory syndrome age age and sex agency all age groups Analysis association Asthma C-statistic Care Case-control case-control study categories Chronic kidney disease chronic liver disease Classifier Comorbidity condition conditions contribute Control coronavirus COVID-19 COVID-19 epidemic Critical care database death deficiency defined demographic data Demographic variables develop diabetes diagnose diagnoses diagnostic digestive system disease distribution drug Electronic health record Electronic health records examined fatal COVID-19 fatal disease frailty Health health condition high risk hospital Hospital admission hospitalisation identify immune include increase in increased risk individual information ischemic heart disease kidney Logistic regression Lower respiratory tract Male sex medical record medical treatment MOST National nervous system Neurological disease nucleic acid test Odds ratio Older age past medical history positive positive test result primary care provided public health Rapid rate ratio Registered reported researcher resident risk risk factor Risk factors risk stratification SARS-CoV-2 selected severe coronavirus disease severe COVID-19 severe disease Sex shielding shown stroke the epidemic type 2 diabetes with COVID-19 [DOI] 10.1371/journal.pmed.1003374 PMC 바로가기 [Article Type] Research Article
Encephalopathy in COVID-19 Presenting With Acute Aphasia Mimicking StrokeNeurology Published on 2020-10-192022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] Abnormalities abnormality absence acute respiratory syndrome Admission agitated Aphasia appear Brain brain MRI CAR-T cerebrospinal fluid Characteristics Chest CT clinical Complication coronavirus COVID-19 CSF Cytokine release syndrome delirium diagnosed electroencephalogram Encephalitis Encephalopathy examination expressive functional heterogeneous Hypoxemia ICANS ICU impairment intravenous low-dose manifestation mechanical ventilation Mild mimicking MRI Nasopharyngeal swab Neuroinflammation neurological Neurological deficit Neurological status Neurological symptom NEUROLOGY neuronal occur Pathogenesis Patient patients positive presenting progressed resolved reverse transcription PCR RT-PCR SARS-CoV-2 Steroids stroke subset Supportive treatment Virus Disease worsened [DOI] 10.3389/fneur.2020.587226 PMC 바로가기 [Article Type] Neurology
Thrombotic Complications in Patients with COVID-19: Pathophysiological Mechanisms, Diagnosis, and TreatmentReview Article Published on 2020-10-192022-10-31 Journal: Cardiovascular Drugs and Therapy [Category] COVID-19, MERS, [키워드] abnormality absence activated acute respiratory distress affected Anticoagulant anticoagulation Antithrombotic association Autopsy clinical outcomes clinician Coagulation Coagulopathy Complication Concentration Consensus contraindications COVID-19 Critical D-dimer develop Diagnosis dysfunction Dyspnoea elevated Evidence feature Features Guidance Hemostasis hospital discharge hospitalized COVID-19 patient identify IMPROVE in-hospital mortality increased risk Inflammation intensity measure microvascular injury MOST Multiorgan Myocardial overlapping Patient patients hospitalized Platelet poor prognosis Prophylaxis Prothrombin time SARS-CoV-2 severe COVID-19 severe COVID-19 disease stroke syndrome Thromboembolism thrombosis Thrombotic complications Treatment Venous Thromboembolism with COVID-19 [DOI] 10.1007/s10557-020-07084-9 PMC 바로가기 [Article Type] Review Article
Can Neuron Specific Enolase Be a Diagnostic Biomarker for Neuronal Injury in COVID-19?Neurology Published on 2020-10-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accompanied acute respiratory syndrome Biomarker Brain Can cerebrospinal fluid China Clinical outcome coronavirus coronavirus disease COVID-19 COVID-19 patient CSF disease disorder elevated Encephalitis Encephalopathy hemorrhages include Infection Injury Intracerebral hemorrhage loss of taste mechanical ventilation Metastasis Mild Neuroinflammation Neurological symptom Neuron neuron specific enolase neuronal nse observation Patient patients Protein Respiratory system SARS-CoV-2 SARS-CoV2 serum stroke Symptom syndrome upper respiratory symptom while White blood cell with COVID-19 [DOI] 10.7759/cureus.11033 PMC 바로가기 [Article Type] Neurology