Assessing vaccine durability in randomized trials following placebo crossover위약 교차 후 무작위 시험에서 백신 내구성 평가Article Published on 2021-11-302022-09-11 Journal: Statistics in medicine [Category] SARS, 임상, [키워드] Assessing assumption Consensus COVID-19 COVID-19 vaccine trial COVID-19 vaccine trials crossover demonstrated develop Efficacy estimation Follow-up hazard implication issue long term occur offered Placebo placebo controlled trial proportional hazards regression randomized trial Regression model Simulation the timing the vaccine Treatment Trial vaccination Vaccine vaccine efficacy vaccine trial vaccine trial design. Volunteer [DOI] 10.1002/sim.9001 PMC 바로가기 [Article Type] Article
EpiCurator: an immunoinformatic workflow to predict and prioritize SARS-CoV-2 epitopesBioinformatics Published on 2021-11-302022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] analyzed antigenic antigenicity approaches assist candidate clinical trial Combination Coronavirus 2019 Coverage COVID-19 demonstrated described effective effective vaccine Effectiveness Efficacy Efficiency EpiCurator epitope Epitopes prediction GISAID database global public health glycoprotein HLA alleles binding affinity IEDB Immune Epitope Database immune response immunogenic potential Immunoinformatic approaches in silico in vitro Interaction pandemic predict Prevent RBD Research retrieved SARS-CoV-2 SARS-CoV-2 epitope SARS-CoV-2 genome SARS-CoV-2 virus sequence spike stability the receptor-binding domain the vaccine TLR triggered variants of concern virus genome virus spread [DOI] 10.7717/peerj.12548 PMC 바로가기 [Article Type] Bioinformatics
Increased B Cell Selection Stringency In Germinal Centers Can Explain Improved COVID-19 Vaccine Efficacies With Low Dose Prime or Delayed BoostImmunology Published on 2021-11-302022-10-31 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Affinity maturation amplifying Antigen appear B cell boost Can center clinical trials complex COVID-19 COVID-19 vaccine Delayed dosage doses dosing interval Effect Effects Efficacy elicited Germinal germinal center (GC) help higher affinity IMPROVE Improved Increased lower dose memory B cell offer paradoxical predicted prime and boost prime-boost immunization prime-boost interval protocols reduced remained resulting SARS-CoV-2 selected Selection the antibody response the vaccine tuning vaccination Vaccine vaccine efficacy [DOI] 10.3389/fimmu.2021.776933 PMC 바로가기 [Article Type] Immunology
Race-ethnicity and COVID-19 Vaccination Beliefs and Intentions: A Cross-Sectional Study among the General Population in the San Francisco Bay AreaArticle Published on 2021-11-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] agency approval Area Asian association belief black Cohort Community concern conducted COVID-19 COVID-19 vaccination COVID-19 vaccine intention demographic factor explained Factor Government group Health Health inequity identify incidence Intention lack LASSO Latinx longitudinal cohort study mediators Other participant Population Predictive Prevalence race–ethnicity Rate reaction receive San Francisco Bay SARS-CoV-2 significantly lower significantly more Support the vaccine vaccination Vaccine white [DOI] 10.3390/vaccines9121406 PMC 바로가기 [Article Type] Article
Role of Vaccine Hesitancy, eHealth Literacy, and Vaccine Literacy in Young Adults’ COVID-19 Vaccine Uptake Intention in a Lower-Middle-Income CountryArticle Published on 2021-11-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adults association Asymptomatic country COVID-19 COVID-19 epidemic COVID-19 vaccine Ehealth literacy ENhance examined globe Government had no Hesitancy information Intention literacy Measures participated positive predictor role the disease the vaccine uptake vaccination Vaccine Vaccine hesitancy vaccine literacy vaccine uptake intention variable [DOI] 10.3390/vaccines9121405 PMC 바로가기 [Article Type] Article
Factors associated with acceptance of COVID-19 vaccine among University health sciences students in Northwest NigeriaResearch Article Published on 2021-11-292022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] 95% CI 95% confidence interval adjusted odds ratio age Characteristics collected country COVID-19 COVID-19 vaccine cross-sectional determinant determine Factor Government Health Science interquartile range median multiple logistic regression Nigeria Pandemics predict predictor prevalence of COVID-19 response Risk perception selected socio-demographic student the vaccine understanding university vaccination Vaccine was used with COVID-19 [DOI] 10.1371/journal.pone.0260672 PMC 바로가기 [Article Type] Research Article
COVID-19 vaccine confidence and hesitancy among health care workers: A cross-sectional survey from a MERS-CoV experienced nationResearch Article Published on 2021-11-292022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Anxiety Candidates Care center Control coronavirus disease COVID COVID 19 COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cross-sectional cross-sectional survey Factor HCW HCWs Health Health care worker identify knowledge less Logistic regression analysis male MERS-CoV MOST National objective outcome pandemic patients prevention questionnaire receive Result Saudi Arabia significantly the vaccine vaccination Vaccine was measured website [DOI] 10.1371/journal.pone.0244415 PMC 바로가기 [Article Type] Research Article
Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodiesBrief Communication Published on 2021-11-292022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] absence addition Antigen binding antibody Biological sciences correlated Critical detectable expressing immunization immunogenic induce Infectious diseases lung Lung inflammation mice Neutralizing antibodies neutralizing antibody S protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine T-cell immunity T-cell Response the vaccine vaccination Vaccines Viral load [DOI] 10.1038/s41541-021-00405-5 PMC 바로가기 [Article Type] Brief Communication
Determinants of COVID-19 Vaccine Hesitancy: A Cross-Sectional Study on a Mexican Population Using an Online Questionnaire (COV-AHQ)Public Health Published on 2021-11-262022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] acceptance adverse effect affected age Alpha analyzed children Contamination coronavirus disease Correlation analysis country COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 vaccination COVID-19 vaccination attitude COVID-19 vaccine COVID-19 vaccine acceptance COVID-19 vaccine awareness COVID-19 vaccine hesitancy in Mexico COVID-19 vaccine Latin-America determinant develop Diagnosis evaluate Gender group help Hesitancy identify imperative in-depth analysis Influenza information Latin America Logistic regression Mild moderate pandemic parent participant Population positive COVID-19 Prevalence public health quarantine significantly Sociodemographic statistical the vaccine vaccination Vaccination strategies Vaccine Vaccine hesitancy Vaccines variable while [DOI] 10.3389/fpubh.2021.728690 PMC 바로가기 [Article Type] Public Health
Licorice ( Glycyrrhiza glabra ) Extracts-Suitable Pharmacological Interventions for COVID-19? A ReviewReview Published on 2021-11-262022-10-28 Journal: Plants [Category] COVID-19, [키워드] acute respiratory distress addition Anti-inflammatory anti-inflammatory drug anti-inflammatory properties Antiviral antiviral drug ARDS clinical trial component contribute coronavirus COVID-19 COVID-19 patients COVID-19 symptoms database develop Glycyrrhetinic acid glycyrrhiza glycyrrhizic acid in vitro in vivo inhibit Intervention licorice mechanism medication medicinal plants Mortality Previous studies Replication review SARS-CoV-2 pandemic shown suggested syndrome the SARS-CoV-2 the vaccine Treatment vaccination was selected Web of Science [DOI] 10.3390/plants10122600 PMC 바로가기 [Article Type] Review