Host- and Species-Dependent Quasispecies Divergence of Severe Acute Respiratory Syndrome Coronavirus-2 in Non-human Primate ModelsMicrobiology Published on 2021-07-092022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 3′-UTR 5′-untranslated region acute respiratory syndrome Analysis average cells coding coronavirus deep sequencing diagnostics Divergence eight evaluated Evolution Frequency genetic information genetic variants Genome Host individual Infection Interpretation longitudinal study lung macaques Model N gene NHPs non-coding region Non-human non-human primate ORF1ab ORF3a ORF8 performed polymorphism primate Protein ranged reported respiratory rhesus macaque rhesus macaques SARS-CoV-2 significantly Single nucleotide polymorphism Single nucleotide variant single-nucleotide SNP SNPs SNVs the SARS-CoV-2 UTR Vaccine variant Variation viral titer virus [DOI] 10.3389/fmicb.2021.694897 PMC 바로가기 [Article Type] Microbiology
Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2Article Published on 2021-07-092022-10-04 Journal: Nature Communications [Category] SARS, 변종, [키워드] ACE2 Analysis angiotensin-converting enzyme-2 antibodies antibody Antibody Response antigenic variation approach B.1.351 variant binding biologic COVID-19 disease COVID-19 patients Critical crystal Efficacy eight escape mutation feature Genetic highlight identify immunology in vitro in vivo Infection Intervention K417N Mutagenesis mutant Mutation NAb natural mutation Neutralizing activity neutralizing antibody overcome overlap Patient potent Protective Protein RBD receptor residue reveal SARS-CoV-2 SARS-COV-2 infection South Africa structural biology the Spike Vaccine virus [DOI] 10.1038/s41467-021-24514-w PMC 바로가기 [Article Type] Article
Use of Immunochromatographic SARS-CoV-2 Antigen Testing in Eight Long-Term Care Facilities for the ElderlyArticle Published on 2021-07-092022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] Antigen antigen test can be used Care clinical validation COVID-19 detect eight elderly facility Germany Health immunochromatographic immunochromatographic SARS-CoV-2 antigen test Infection information Long-term care LTC LTCs Minden mitigate Moers POCT—point of care testing polymerase chain Prevent Rapid resolved reverse transcription Roche RT-PCR SARS-CoV-2 SARS-CoV-2 antigen specificity Spread Testing threshold USA virus [DOI] 10.3390/healthcare9070868 PMC 바로가기 [Article Type] Article
Telemedicine interventions for hypertension management in low- and middle-income countries: A scoping reviewResearch Article Published on 2021-07-092022-10-28 Journal: PLoS ONE [Category] Coronavirus, SARS, [키워드] approach articles benefit blood pressure cardiovascular disease Care changes in Characteristics Clinical outcome clinical outcomes clinical trial counseling country COVID-19 pandemic current database demonstrated Diastolic blood pressure eight event Evidence FIVE Health heterogeneity hypertension Impact IMPROVE income Intervention intervention group limit limitation magnitude majority management middle objective offer outcome Patient protocol ranged reduction in Registered reported Result sample sizes screened short duration Systolic blood pressure Telemedicine telemedicine intervention unique vulnerable patient were used [DOI] 10.1371/journal.pone.0254222 PMC 바로가기 [Article Type] Research Article
Endodontic Emergencies in Mumbai City during COVID-19 Lockdown and Different Phases of UnlockArticle Published on 2021-07-082022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] age analyzed average body temperature carried city clinician college COVID-19 COVID-19 pandemic Critical dental Descriptive analysis diagnose Diagnosis eight Emergency Endodontic endodontic emergency epidemiologic investigation equipment highest hospital Intensive lockdown majority male Mumbai Mumbai metropolitan region oxygen saturation Pain parameter Patient phase positive Protective Registered reported required Research seeking Sex shielding significantly higher Stage stages subsequent symptomatic Symptoms tested the patient tooth Travel Treatment verbal verbal numerical rating scale vital pulp therapy was performed with COVID-19 [DOI] 10.3390/ijerph18147314 PMC 바로가기 [Article Type] Article
Key summary of German national treatment guidance for hospitalized COVID-19 patients Key pharmacologic recommendations from a national German living guideline using an Evidence to Decision Framework (last updated 17.05.2021)Original Paper Published on 2021-07-062022-10-29 Journal: Infection [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] added analyses Analysis anticoagulation bleeding Consensus Corticosteroid COVID-19 decision eight Evidence executive framework Guidance Hospitalized hospitalized COVID-19 patient hospitalized patient IL-6 antagonist Inpatient Interpretation Intervention Ivermectin Living guideline Living meta-analysis Meta-analysis National Patient plasma progressive disease Prophylactic recommendation Result risk risk factor routine care SARS-CoV-2 SARS-COV-2 infection selected Standard of care supplemental oxygen supported systematic review therapy Tocilizumab Treatment Venous Thromboembolism VTE WHO with COVID-19 [DOI] 10.1007/s15010-021-01645-2 PMC 바로가기 [Article Type] Original Paper
Lack of consideration of sex and gender in COVID-19 clinical studiesArticle Published on 2021-07-062022-10-04 Journal: Nature Communications [Category] SARS, 임상, 치료법, [키워드] analyses Analysis Clinical outcome clinical study clinical trial clinical trials collecting data COVID-19 COVID-19 mortality develop eight Epidemiology Frequency Gender Health policy incidence include Inclusion investigated pharmacological recruitment Registered Risk factors SARS-CoV-2 SARS-COV-2 infection severity Sex Sex difference Side effects Therapeutic approach Vaccine [DOI] 10.1038/s41467-021-24265-8 PMC 바로가기 [Article Type] Article
Navigating Infodemics, Unlocking Social Capital and Maintaining Food Security during the COVID-19 First Wave in the UK: Older Adults’ ExperiencesArticle Published on 2021-07-062022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] addition Adults age analysed approach burden Capital Community conducted COVID-19 COVID-19 infections eight experience food food insecurity group healthy Importance independent Isolation limit lockdown loneliness maintaining Measures National offer Older older adult participant Participants public health public health messaging researchers rising secure security social connectedness social contact Wave [DOI] 10.3390/ijerph18147220 PMC 바로가기 [Article Type] Article
‘de Novo’ repurposing of Daflon as anti-intestinal parasitic drug in experimental giardiasisResearch article Published on 2021-07-012022-10-05 Journal: Experimental Parasitology [Category] 신약개발, [키워드] Albino Analysis antidiabetic drug assigned Combined therapy control group days post-infection demonstrated develop dismutase drug Drug administration drug resistance Efficiency eight epithelial European country experimental group Frequency Giardia giardiasis histopathological in vivo indicated inoculated intestinal material MDA metronidazole mice multiple dose murine model objective oxidative stress Progressive reduced Result retained Safe significantly small intestine Stage tissue treated widespread [DOI] 10.1016/j.exppara.2021.108124 [Article Type] Research article
Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method일종의 동적 CNN 변형 방법을 이용한 코로나19 흉부 X선 및 CT 영상 분류Article Published on 2021-07-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] Accuracy applied Bacterial bacterial pneumonia Chest chest X-ray Chest X-Ray and CT images classification CNN computerised tomography Control COVID-19 COVID-19 case COVID-19 cases COVID-19 detection COVID-19 diagnosis CXR dataset deep deep learning Diagnosis eight evaluate feature generalisability healthcare IMPROVE Infection lack Modification Modified CNN. Non-COVID-19 Pneumonia Precision problems Research sensitivity Tuberculosis understanding vanishing Viral pneumonia [DOI] 10.1016/j.compbiomed.2021.104425 PMC 바로가기 [Article Type] Article