Applying lessons from the Ebola vaccine experience for SARS-CoV-2 and other epidemic pathogensPerspective Published on 2020-06-152022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] applied Applying caused coronavirus disease COVID-19 Critical development Drug development Drug regulation Ebola Ebola vaccine Ebola virus disease effort Epidemic experience global pandemic highlight Inc. MSD Novel coronavirus pathogen Pathogens Regulatory respiratory SARS-CoV-2 Sharp USA Vaccine Vaccine development virus Zaire [DOI] 10.1038/s41541-020-0204-7 PMC 바로가기 [Article Type] Perspective
Working Hard or Hardly Working? Regulatory Bottlenecks in Developing a COVID-19 VaccineArticle Published on 2020-06-132023-06-23 Journal: Trends in Biotechnology [Category] SARS, 신종인플루엔자, [키워드] COVID-19 innovation speed Regulation Vaccine development [DOI] 10.1016/j.tibtech.2020.06.004 PMC 바로가기
Antibody testing for COVID-19: A report from the National COVID Scientific Advisory PanelResearch Article Published on 2020-06-112022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] 95%CI acute respiratory syndrome antibodies antibody Antibody detection approach calibrated caused Control coronavirus COVID COVID-19 COVID-19 pandemic Diagnosis ELISA Epidemiology estimate evaluate exposure first symptoms IgG IgG level IgM IgM and IgG immunoassay individual Infection lateral flow lateral flow immunoassay LFIA limit negative control sample nine Panel Patient PCR plasma plasma sample Point quarantine ranged remained RT-PCR Safe SARS-CoV-2 SARS-CoV-2 IgM sensitivity serology specificity Support symptom onset tested threshold titre Vaccine development [DOI] 10.12688/wellcomeopenres.15927.1 PMC 바로가기 [Article Type] Research Article
Natural Products as Potential Leads Against Coronaviruses: Could They be Encouraging Structural Models Against SARS-CoV-2?Review Published on 2020-06-112022-10-30 Journal: Natural Products and Bioprospecting [Category] COVID-19, [키워드] acute respiratory syndrome Against against SARS-CoV Antiviral antiviral activity antiviral drug applied caused conducted coronavirus Coronavirus disease 2019 Coronavirus-2 Coronaviruses COVID-19 Encouraging genomic sequence Infectious disease inhibitory medicinal plants MERS Middle East Model natural natural products New notable plant positive-sense single-stranded RNA Potential product reported researcher RNA genome SARS-CoV SARS-CoV-2 similarity syndrome treat Treatment Vaccine development WHO worldwide pandemic β-Coronaviruses [DOI] 10.1007/s13659-020-00250-4 PMC 바로가기 [Article Type] Review
COVID-19: Guidelines for pharmacists in South AfricaGuideline Published on 2020-06-102022-10-28 Journal: Southern African Journal of Infectious Diseases [Category] COVID-19, [키워드] allergic rhinitis angiotensin receptor blocker ARBs Chloroquine Community Contact Corona Virus Disease coronavirus disease COVID-19 Critical Department Evidence Guidance guideline Healthcare system hospital Hydroxychloroquine include Incubation period Influenza information management Medicine MERS-CoV novel coronavirus (2019-nCoV) NSAIDS outbreak pandemic Patient patients with COVID-19 recommendations SARS-CoV SARS-CoV-2 social media South Africa spill-over Transmission Vaccine development virus website WHO World Health Organization [DOI] 10.4102/sajid.v35i1.206 PMC 바로가기 [Article Type] Guideline
Physicochemical properties of SARS‐CoV‐2 for drug targeting, virus inactivation and attenuation, vaccine formulation and quality controlReview Published on 2020-06-082022-10-31 Journal: Electrophoresis [Category] COVID-19, SARS, [키워드] acute respiratory syndrome adjuvants approach approval average buffer centrifugation competent condition conditions coronavirus COVID‐19 downstream Effects epitope example feasible Formulation immunologically inactivation information knowledge membranes Physicochemical properties Protein Quality control Radiation rigidity SARS‐CoV‐1 SARS‐CoV‐2 SARS‐CoV solvent stability Support susceptibility temperature transfer UV light Vaccine Vaccine development virus virus inactivation [DOI] 10.1002/elps.202000121 PMC 바로가기 [Article Type] Review
SARS-CoV-2 (COVID-19) Vaccine Development and Production: An Ethical Way ForwardSARS-CoV-2(COVID-19) 백신 개발 및 생산: 윤리적인 방법Research Article Published on 2020-06-052022-08-31 Journal: Cambridge Quarterly of Healthcare Ethics [Category] SARS, 신약개발, 임상, [키워드] COVID-19 COVID-19 disease development distribution Efficacy failure Forward Government Health Healthcare system healthy herd immunity Immunity immunization novel vaccines produced recipients reduce SARS-CoV-2 SARS-CoV-2 virus subject Vaccine Vaccine development vaccine testing Vaccines widespread [DOI] 10.1017/S096318012000047X PMC 바로가기 [Article Type] Research Article
Could Coronavirus Disease 2019 (COVID-19) Render Natural Immunity to Re-infections? A Spotlight on the Therapeutic PipelineImmunology Published on 2020-06-052022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Adaptive immunity antibody-dependent enhancement (ADE) convalescent plasma COVID-19 natural Vaccine development [DOI] 10.3389/fimmu.2020.01294 PMC 바로가기 [Article Type] Immunology
Vaccines Against Antimicrobial ResistanceReview Published on 2020-06-032024-09-02 Journal: Frontiers in immunology [Category] 대상포진, [키워드] antimicrobial resistance (AMR) Infectious diseases mechanisms of antibiotic resistance Vaccine development Vaccines vaccinology [DOI] 10.3389/fimmu.2020.01048 PMC 바로가기 [Article Type] Review
Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patientsArticle Published on 2020-06-012022-10-04 Journal: Nature Communications [Category] SARS, 진단, 치료기술, 치료법, [키워드] Alter antibodies antibody B-cell B-cell epitope coronavirus COVID-19 convalescent patients COVID-19 patient diagnostic diagnostics elicit fusion peptide help human antibody response identify IgG immunodominant immunogenic linear linear epitope neutralising neutralising antibody overlapping Patient peptides Receptor binding domain Region SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 spike glycoprotein SARS-CoV-2 spike protein sera serological test serology significantly spike glycoprotein Spike protein target targets the SARS-CoV-2 vaccine candidate Vaccine development Vaccines viral infection Virus neutralisation [DOI] 10.1038/s41467-020-16638-2 PMC 바로가기 [Article Type] Article