Relationship between Influenza Vaccination Coverage Rate and COVID-19 Outbreak: An Italian Ecological StudyArticle Published on 2020-09-162022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome Admission analyses Analysis anti-influenza vaccination approach Beta clinical expression coronavirus coronavirus disease coronavirus spread correlated Coverage COVID-19 COVID-19 symptom COVID-19 symptoms death diffusion drug Hospitalization Influenza influenza vaccination coverage rate intensive care unit investigated Italian Italian population lack less multivariable analyses outcome pandemic disease R 2 Rate reduce reduced relationship SARS-CoV-2 SARS-CoV-2 seroprevalence Spread spread of COVID-19 vaccination Vaccine [DOI] 10.3390/vaccines8030535 PMC 바로가기 [Article Type] Article
Preventive behavior of Vietnamese people in response to the COVID-19 pandemicResearch Article Published on 2020-09-092022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI Administered alcohol Beta body temperature calculated Community concerning confidence cough COVID-19 COVID-19 pandemic death Effect Epidemiology evaluate Face mask Health Infection information interval Local lockdown Perceived physical distancing preventive measure preventive measures professional questionnaire recorded the epidemic Travel Vietnamese people [DOI] 10.1371/journal.pone.0238830 PMC 바로가기 [Article Type] Research Article
Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014Research Article Published on 2020-08-102022-10-28 Journal: PLoS ONE [Category] COVID-19, Fulltext, MERS, 조류인플루엔자, [키워드] amplification Analysis bat Beta chain China Consensus Coronaviridae coronavirus coronavirus coronavirus RNA Coronaviruses detect excreta highlight increase indicate majority Malayan porcupine mechanism MOST multiple coronaviruses Novel coronavirus pandemic positive sample Previous studies proportion public health threat raised reaction risk rodent rodents SARS-CoV-2 significantly increased suggested Transmission viral family zoonotic zoonotic spillover [DOI] 10.1371/journal.pone.0237129 PMC 바로가기 [Article Type] Research Article
Developing a holistic contingency plan: Challenges and dilemmas for cancer patients during the COVID‐19총체적 비상 계획 개발: COVID-19 기간 동안 암 환자의 도전과 딜레마Review Published on 2020-07-202022-09-10 Journal: Cancer Medicine [Category] 임상, [키워드] 2019 novel coronavirus 2019 novel coronavirus disease Beta beta coronavirus Cancer cancer patient Cancer patients Care challenge Chronic disorder chronic disorders clinical trial clinical trials contingency plan coronavirus coronavirus disease COVID‐19 COVID‐19 Developing disease Effect emotional emotional support Evidence expected Health Health care Health care system health care systems Healthcare system Healthcare systems implementation include indirect effect indirect effects management morbidity and mortality Novel coronavirus novel coronavirus disease pandemic Pandemics Participation Patient prevention Psychoeducation respiratory responsible Safe Support Treatment [DOI] 10.1002/cam4.3271 PMC 바로가기 [Article Type] Review
Effectiveness of Interferon Beta 1a, compared to Interferon Beta 1b and the usual therapeutic regimen to treat adults with moderate to severe COVID-19: structured summary of a study protocol for a randomized controlled trialLetter Published on 2020-06-032022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 95% confidence interval Adjusted analysis Administered Admission age alcohol allocation concealment ALT/AST Analysis Arm arrhythmia assigned Beta block-randomization Blood calculated Care center clinical Clinical improvement clinical trial conducted confirmed case control group cough COVID-19 COVID-19 confirmed patient COVID-19 in patient COVID-2019 Cox proportional-hazards model death discharge disease dissemination drug Duration education Effectiveness element eligibility enrolled excluded exclusion criteria fatigue follow-up time hazard headache Health hospital hospital discharge Hospitalization Hydroxychloroquine + Lopinavir/Ritonavir improvement include Interaction Interferon beta-1a Interferon-β 1a Interferon-β 1b intervals intervention group investigator Kaletra Kaplan–Meier laboratory result lactating women Last limit log-rank test Loghman Hakim Hospital Lopinavir Lopinavir/ritonavir masking mechanical ventilation Medical Science Medical Sciences moderate Mortality myalgia nasal NCT04343768 number objective open label Open-label Other outcome oxygen saturation package parallel group participant Patient performed positive pregnant Primary outcome primary outcome measure problem professional protocol pulse-oximetry R software R version 3.6.1 randomization randomization sequence Randomized Randomized controlled trial Randomly reached receive Recigen recruitment refusal regimen Registered Research respiratory rate RT-PCR test Sample SARS-CoV-2 sealed secondary secondary outcome seven-category ordinal scale single center single dose SpO2 sputum production standard care status Study protocol Symptom temperature tested the patient therapeutic three groups time treat treated treatment groups Trial university version 3.6.1 website World Health Organization Ziferon [DOI] 10.1186/s13063-020-04382-3 PMC 바로가기 [Article Type] Letter
Computed tomography manifestations in super early stage 2019 novel coronavirus pneumonia초초기 2019년 신종 코로나바이러스 폐렴의 컴퓨터 단층 촬영 징후Chest Imaging Published on 2020-05-212022-09-01 Journal: Acta Radiologica (Stockholm, Sweden : 1987) [Category] 진단, [키워드] 2019 novel coronavirus Beta beta coronavirus can be used caused Chain Reaction characteristic Chest computed tomography Chest CT Chest CT image China clinically suspected Computed tomography consolidation coronavirus Coronavirus infection Coronavirus pneumonia COVID-19 COVID-19 infection Diagnosis Disease progression dominant early stage enrolled epidemiological Evidence feature Follow-up GGO ground-glass opacity Infection initial initial screening initial stage lesion lesions manifestation Material and Method New coronavirus nine nodule Novel coronavirus novel coronavirus pneumonia nucleic acid onset of symptoms outbreak Patient patients piece pleura Pneumonia pneumonia case pneumonia cases polymerase chain polymerase chain reaction progressed Result reverse transcription reverse transcription polymerase chain reaction RT-PCR the disease thin chest CT tomography were recorded Wuhan [DOI] 10.1177/0284185120924806 PMC 바로가기 [Article Type] Chest Imaging
The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders11번 염색체에 있는 새로운 유전자간 변이의 파생된 대립유전자는 그린랜더의 낮은 체질량 지수 및 유리한 대사 표현형과 관련이 있습니다Research Article Published on 2020-01-242022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adipose Adipose tissue affected affecting Alaska allele alteration Analysis analysis Arctic association Author Beta biological processe biological processes BMI body mass body mass index body-mass body-mass index cholesterol chromosome chromosome 11 Cohort cohorts contribute derived allele expand Fat mass Frequency G allele G-allele Genetic genetic architecture genetic loci Genetic predisposition Genetic variant genetic variants genome-wide significant HDL-cholesterol identify independent insulin insulin resistance knowledge lean mass measure mechanism Meta-analysis Native obesity performed phenotype physical activity populations remained replicate Replication required risk significantly Stage stage 2 study population target targets the stage tissue traits Treatment Triglyceride variant visceral Waist circumference weight were assessed [DOI] 10.1371/journal.pgen.1008544 PMC 바로가기 [Article Type] Research Article
The Porcine Deltacoronavirus Replication Organelle Comprises Double-Membrane Vesicles and Zippered Endoplasmic Reticulum with Double-Membrane SpherulesArticle Published on 2019-11-052022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] addition Beta cell interaction cellular membrane characterized coronavirus country Culture diarrhea DMV double-membrane spherule Double-membrane vesicle Endoplasmic reticulum Hong Kong induce infected cell Infectious Bronchitis Virus Initially membrane membranes Microscopy organelle other coronavirus Porcine deltacoronavirus progeny protein synthesis question Region Replication Replication organelle Reticulum RNA virus spherule spherules strain Structure Support tissue USA Vesicle vesicles viral RNA synthesis virus virus replication were assessed zippered ER [DOI] 10.3390/v11111030 PMC 바로가기 [Article Type] Article
Identification of Alpha and Beta Coronavirus in Wildlife Species in France: Bats, Rodents, Rabbits, and HedgehogsArticle Published on 2017-11-292022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] alphacoronavirus bats Beta circulation coronavirus coronavirus cross emerging disease events France genetic diversity hedgehog hedgehogs humans identification MERS-CoV Middle East Prevent respiratory rodents SARS-CoV Specy virus strains wild rabbits wildlife [DOI] 10.3390/v9120364 PMC 바로가기 [Article Type] Article
The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli메실리남 저항체는 대장균에서 세포벽 합성을 자극하는 펩티도글리칸 엔도펩티다제의 역할을 밝힙니다Research Article Published on 2017-07-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activating Activation addition allele Analysis Antibiotics approach Bacterial bacterial cell bacterial cells Beta Beta-lactam beta-lactam antibiotics beta-lactam mecillinam biogenesis build Cell cell wall cell wall synthesis cells characterization cleave cleaving complexes comprehensive resource contrary crosslink crosslinking crosslinks dataset downstream analysis drug drug resistance E . coli effective enzyme Enzymes Escherichia coli expand generate Genetic genetic background genetic loci Genome identify implicated induction inhibit involved killing loci locus mechanism mecillinam modulating mutant mutants organism overproduction PBP2 PBPs penicillin penicillin-binding protein penicillin-binding proteins performed PG synthase PG synthesis probe promote Reasoning required resource response reveal Stress stress response subset Synthase target the cell Tn-seq Tn-Seq analysis transpeptidase utility wild-type cells [DOI] 10.1371/journal.pgen.1006934 PMC 바로가기 [Article Type] Research Article