The early immune response to infection of chickens with Infectious Bronchitis Virus (IBV) in susceptible and resistant birdsResearch Article Published on 2015-10-092022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] Affect analysed Bacterial infection biological pathway can be used candidate gene cause chicken contagious coronavirus disease Disease resistance Effect evaluated examined expression functional Gene Expression gene expression differences Genetic Genome help Host host response IBV IBV infection identify immune response Infection Infectious Bronchitis Virus innate immune response involved lesion Microarray Mortality occur Post-infection Potential reproductive resistance gene Respiratory disease responsible Result selective subsequent supplementary material susceptible target the disease tissue tracheal vaccination virus were used [DOI] 10.1186/s12917-015-0575-6 PMC 바로가기 [Article Type] Research Article
Identification and pathogenicity of a variant porcine epidemic diarrhea virus field strain with reduced virulenceShort Report Published on 2015-06-122022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] C-terminus cause characterized China Complete contagious disease epidemic diarrhea finding Genome high mortality rate identification indicated Mild Newborn North America pathogenicity pathology PEDV Phylogenetic tree Porcine epidemic diarrhea virus prevalent reduced Reduced virulence S gene spike gene Spread strain variant Vero Cell virulence virus was used [DOI] 10.1186/s12985-015-0314-4 PMC 바로가기 [Article Type] Short Report
Development of a real-time reverse transcription loop-mediated isothermal amplification method for the rapid detection of porcine epidemic diarrhea virusResearch Published on 2015-05-142022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] characterized clinical sample clinical samples Clinical studies contagious detect detection Detection limit develop development diarrhea disease epidemic diarrhea equipment isothermal amplification Laboratory less outbreak PEDV real-time RT-PCR Result reverse transcription RNA RT-LAMP RT-PCR sensitivity specimens the epidemic virus viruses vomiting watery [DOI] 10.1186/s12985-015-0297-1 PMC 바로가기 [Article Type] Research
Molecular Characterization and Phylogenetic Analysis of Porcine Epidemic Diarrhea Viruses Associated with Outbreaks of Severe Diarrhea in Piglets in Jiangxi, China 2013Research Article Published on 2015-03-192022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] accumulated Amino acid amino acid substitution Analysis analyzed antigenic caused change Characteristics characterization characterized China Chinese Complete contagious death diarrhea Effectiveness epidemic diarrhea epitope Genetic Genetic variation Genome genome sequence hydrophilicity identify identity less Multiple Mutation N gene Neutralizing nucleotide ORF1a/b ORF3 outbreak PEDV proximal ranged S gene strain Strains structural protein unique Vaccine viral disease virus viruses vomiting watery [DOI] 10.1371/journal.pone.0120310 PMC 바로가기 [Article Type] Research Article
The avian coronavirus spike proteinArticle Published on 2014-10-172022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Gammacoronavirus affecting Amino acid attachment protein avian coronavirus binding cause Cell Cell culture cells circulating contagious coronavirus disease effort focus Host IBV in vivo Infectious Bronchitis Virus Infectious bronchitis virus IBV Intervention organ other tissue Pathogenesis Protective reproductive respiratory tract S1 domain serotype spike Spike protein Spike proteins strain therapeutic tissue tissue tropism tissues tropism Variation virus [DOI] 10.1016/j.virusres.2014.10.009 PMC 바로가기 [Article Type] Article
H7N9: A killer in the making or a false alarm?Review Published on 2014-07-012023-06-02 Journal: Canadian journal of microbiology [Category] 조류인플루엔자, [키워드] contagieux contagious H7N9 infectieux infectious Influenza pandemic Pandemie [DOI] 10.1139/cjm-2014-0186 [Article Type] Review
Transcriptome analysis of chicken kidney tissues following coronavirus avian infectious bronchitis virus infectionResearch Article Published on 2013-10-302022-10-28 Journal: BMC Genomics [Category] Coronavirus, MERS, [키워드] Analysis analyzed Antiviral Apoptosis bronchitis cascade cause Cell compared conducted contagious contributed coronavirus cytokine differential expression differentially expressed gene down-regulated Gene Gene expression profiling Genes Host host defense response Host transcriptional response IBV IBV infection identify IL6 immune immune responses immune-related gene Infection infectious Infectious Bronchitis Virus Inflammatory response innate immune Interaction involved IRF1 KEGG pathway kidney kidney tissue kidney tissues knowledge mechanism Microarray molecular MOST MYD88 NFKB2 Ontology Pathogenesis pathway positive provided real-time RT-PCR Regulation related Result Signal transduction Stat1 the Coronaviridae Transcriptome transcriptome analysis up-regulated upper respiratory tract virus [DOI] 10.1186/1471-2164-14-743 PMC 바로가기 [Article Type] Research Article
Inhibitory Effect of Resveratrol against Duck Enteritis Virus In VitroResearch Article Published on 2013-06-112022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] addition age Cell Concentration contagious disease dose-dependent manner duck early stage Effect Enteritis exhibit expression fibroblast found host cells immunofluorescence assay impacted in vitro inactivation Infected Infection inhibit inhibitory activity Mortality nucleus plant Post-infection Protein Replication responsible resveratrol supported suppressed ultrastructure Viral protein virus virus multiplication virus nucleic acid virus replication [DOI] 10.1371/journal.pone.0065213 PMC 바로가기 [Article Type] Research Article
In vitro inhibition of transmissible gastroenteritis coronavirus replication in swine testicular cells by short hairpin RNAs targeting the ORF 7 geneResearch Published on 2012-08-282022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] Apoptosis approach assays Cell cell proliferation characterized contagious Coronavirus replication Cytopathic effect demonstrated diarrhea effective Efficiency Evidence examined expressing expression expression plasmid expression plasmids gastroenteritis Genome high mortality in vitro indicated Infection inhibit inhibited inhibitory effect N gene ORF ORF 7 Quantitative Replication reporter Result RNA RNA interference RT-PCR analysis selected sequence short hairpin RNA shown significantly specificity STABLE target gene TCID TGEV the vaccine therapeutic transmissible gastroenteritis virus Treatment viral disease viral infections viral replication virus virus replication virus titer vomiting [DOI] 10.1186/1743-422X-9-176 PMC 바로가기 [Article Type] Research
S1 gene sequence analysis of a nephropathogenic strain of avian infectious bronchitis virus in EgyptResearch Published on 2006-09-202022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] alignment alimentary tract Amino acid Analysis antibody Antigen bronchitis changes in characterized contagious country criteria cross-protective disease Endemic gene sequence genotyped histopathological Histopathology homology IBV include Infected Infectious Bronchitis Virus inoculation isolate kidney mass Massachusett moderate Mortality oviduct performed protection raise related renal respiratory tract tissues Result RT-PCR sequence sequence homology Serologically serotype strain the disease the S1 protein tonsil tracheal tropism Vaccine virus [DOI] 10.1186/1743-422X-3-78 PMC 바로가기 [Article Type] Research