Alveolar barrier disruption in varicella pneumonia is associated with neutrophil extracellular trap formationResearch Article Published on 2020-11-052023-05-31 Journal: JCI Insight [Category] Fulltext, 두창, 수두, 홍역, [키워드] Innate immunity Molecular pathology Neutrophils Pulmonology Virology [DOI] 10.1172/jci.insight.138900 PMC 바로가기 [Article Type] Research Article
Different Clinical Presentations and Outcomes of Disseminated Varicella in Children With Primary and Acquired ImmunodeficienciesOriginal Research Published on 2020-11-052024-09-02 Journal: Frontiers in immunology [Category] 대상포진, [키워드] disseminated varicella Innate immunity primary immumunodeficiencies Steroids varicella [DOI] 10.3389/fimmu.2020.595478 PMC 바로가기 [Article Type] Original Research
The COVID-19 pandemic through eyes of a NYC fertility center: a unique learning experience with often unexpected resultsResearch Published on 2020-11-042022-10-29 Journal: Reproductive Biology and Endocrinology : RB&E [Category] COVID-19, SARS, [키워드] absence adaptive addition affected Anti-viral Anti-viral immunity antibody appear available data cellular classical coast Combination Consensus country Course COVID virus strains COVID-19 COVID-19 and infertility COVID-19 pandemic described East Evidence eye First wave Guidance Health herd immunity hypothese immune response Immunity Infection Infectivity Influenza initial Innate immunity Lineage measure Mutation New York City offer pandemic Patient patients phenotype predict proceed Region regions remained SARS-CoV-2 virus second wave suggested unique unlikely Vaccine virus West [DOI] 10.1186/s12958-020-00663-3 PMC 바로가기 [Article Type] Research
Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 MortalityArticle Published on 2020-11-032023-06-16 Journal: Cell [Category] MERS, SARS, [키워드] antibodies COVID-19 Dynamics Fc receptors Innate immunity SARS-CoV-2 [DOI] 10.1016/j.cell.2020.10.052 PMC 바로가기 [Article Type] Article
New Insights in Laboratory Testing for COVID-19 Patients: Looking for the Role and Predictive Value of Human epididymis secretory protein 4 (HE4) and the Innate Immunity of the Oral Cavity and Respiratory TractArticle Published on 2020-11-022022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Accuracy Admission affected age Analysis anti-inflammatory activity Antiviral AUC Autoimmune disease Biomarker Blood level Breast carcinoma caused Cavity Chemotherapy clinical evolution clinical manifestation correlation COVID COVID-19 COVID-19 patient Critical CRP Defense demonstrated died disorder evaluate Evolution Factor fibrosis hospital Hospital stay Host Human Human epididymis secretory protein 4 (HE4) identify IL-6 IL-6 level IL6 Inclusion Inflammatory biomarker Innate Innate immunity insight Interleukin-6 (IL-6) involved Laboratory test lung lung carcinoma mechanism men Mild MONITOR monoclonal antibodies nasal nasopharynx natural immunity New new coronavirus SARS-CoV-2 oral ovarian pandemic parameter Patient PCT performed positive Predictive presepsin (PSP) procalcitonin procalcitonin (PCT) Protein PSP Radiotherapy renal respiratory respiratory tract RNA virus ROC Curve role SARS-CoV-2 serum Significant Symptom Testing the disease tract Treatment value venous viruses were excluded women [DOI] 10.3390/microorganisms8111718 PMC 바로가기 [Article Type] Article
What the physicians should know about mast cells, dendritic cells, urticaria, and omalizumab during COVID-19 or asymptomatic infections due to SARS-CoV-2?Review Published on 2020-11-012023-07-12 Journal: Dermatologic therapy [Category] SARS, [키워드] COVID-19 dendritic cells Innate immunity Mast cells SARS-CoV-2 urticaria [DOI] 10.1111/dth.14068 [Article Type] Review
Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19 Research Published on 2020-11-012022-10-05 Journal: Nature Immunology [Category] SARS, 임상, 진단, 치료기술, [키워드] Analysis Autopsy Bioinformatics analysis Cell circulating Cohort COVID-19 Endothelial cell Express expression hospitalized patient humoral immunohistochemistry Increased independent Inflammation Innate immunity involved Long lung marker mononuclear cells Mortality multivariable analysis pathogen patients patients with COVID-19 Peripheral blood plasma concentration prognostic prognostic indicator Ptx3 Regulation RNA-sequencing selected single-cell with COVID-19 [DOI] 10.1038/s41590-020-00832-x [Article Type] Research
Robust expression of p27Kip1 induced by viral infection is critical for antiviral innate immunityArticle Published on 2020-11-012023-06-23 Journal: Cellular microbiology [Category] 신종인플루엔자, [키워드] antiviral responses influenza A virus Innate immunity iTRAQ NS1 protein p27Kip1. [DOI] 10.1111/cmi.13242
Trusting a gut feeling: the potential of a newly refined human intestinal enteroid model to evaluate viral-host interactionsComment Published on 2020-11-012023-07-11 Journal: The Journal of Physiology [Category] SARS, [키워드] human intestinal enteroid Innate immunity Microbiome SARS-CoV-2 Toll-like receptors viral-host interactions. [DOI] 10.1113/JP280368 [Article Type] Comment
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity파파인 유사 프로테아제는 SARS-CoV-2 바이러스 확산 및 선천 면역을 조절합니다Article Published on 2020-11-012022-09-11 Journal: Nature [Category] Fulltext, SARS, 변종, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral antiviral immune response antiviral immunity attenuate biochemical cleavage cleave cleaving complex contribute coronavirus crystal structure cytopathogenic effect domain dual enzyme functional generate high affinity highlight highlighting Host host protein host proteins immune responses impair implicated infected cells Infection Innate immunity Interaction interactions interferon interferon pathway interferon-stimulated gene IRF3 ISG15 maintain mechanism NF-κB NF-κB pathways Papain-like protease PLPro polyprotein post-translational modification promote protease Protein reduce regulate Regulation required respiratory responses reveal SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral sequence identity severe acute respiratory syndrome Coronavirus specificity Spread suppress target therapeutic strategy type I interferon ubiquitin Viral viral replication viral spread [DOI] 10.1038/s41586-020-2601-5 PMC 바로가기 [Article Type] Article